Impact of Soylent Consumption on Human Microbiome Composition

NCT03203044 | Completed

• 1 other identifier: soylentmicrobiomeproject
• Study Type: interventional
• Target: 14
• Locations: 0 countries
• Sites: N/A

Brief Summary

Soylent 2.0 is a popular meal replacement drink that is used to supplement or replace one's regular diet. Soylent is designed to fully fulfill one's nutritional needs, but its impact on the human microbiome remains unknown. This study aims to track the composition of participants' gut microbiomes before, during, and after Soylent consumption to more holistically understand its impact on microbiome health. We predict that a short term Soylent-based diet will induce observable and reversible changes to participants' gut microbiomes.

Conditions

Gut Microbiota

Keywords

Dietary Intervention

Outcome Measures

Primary Outcomes (1)

• Changes to gut microbiome composition as a result of an interventional Soylent diet

  Days 3-6 of the study

Study Arms (2)

Regular Diet Arm

NO INTERVENTION

Maintains a regular diet for the duration of the study.

Soylent Diet Arm

EXPERIMENTAL

Receives a Soylent dietary intervention on days 3-6 of the study.

Other: Soylent and water diet

Interventions

Soylent and water diet OTHER

A diet of five servings of Soylent 2.0 liquid meal-replacement drink per day and water as needed.

Soylent Diet Arm

Eligibility Criteria

• Age: 18 Years - 30 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• The subject population will consist of undergraduate UC Berkeley students.

You may not qualify if:

• Dietary allergies or sensitivities to Soylent 2.0 ingredients
• Vulnerable individuals as defined by Committee for Protection of Human Subjects guidelines
• Individuals with health issues
• Individuals who take antibiotics, probiotics, alcohol, or supplements.

Sponsors & Collaborators

• University of California, Berkeley: lead

Study Officials

• Adam P Arkin, PhD

  Professor

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Model Details: Participants are separated into two diet arms. The regular diet arm remains on a self-reported regular diet for the duration of the study. The Soylent diet arm maintains a regular diet for two days, switches to an all Soylent and water diet for four days, and returns to a regular diet for four days.

Study Record Dates

• First Submitted: June 27, 2017
• First Posted: June 29, 2017
• Study Start: October 10, 2016
• Primary Completion: November 16, 2016
• Study Completion: November 16, 2016
• Last Updated: June 29, 2017

Record last verified: 2017-06

Data Sharing

• IPD Sharing: Will share