NCT03201536

Brief Summary

Zipline incision approximation vs. Suture -- zips 3 study. A prospective, multi-site, non-blinded, randomized controlled, study designed to evaluate user preferences associated with use of the zipline 3 system versus conventional suturing for incision closure.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Oct 2012

Geographic Reach
1 country

3 active sites

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 21, 2012

Completed
4 months until next milestone

Study Start

First participant enrolled

October 1, 2012

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2012

Completed
4.7 years until next milestone

First Posted

Study publicly available on registry

June 28, 2017

Completed
Last Updated

June 28, 2017

Status Verified

June 1, 2017

Enrollment Period

Same day

First QC Date

May 21, 2012

Last Update Submit

June 26, 2017

Conditions

Keywords

ZipLine3 device vs. conventional sutures

Outcome Measures

Primary Outcomes (1)

  • Wound healing

    Wound healing as judged by the CVAS (Cosmetic Visual Analogue Scale) wound healing scale

    3-month

Secondary Outcomes (1)

  • time of procedure

    immediately

Study Arms (2)

sutures

ACTIVE COMPARATOR

zipLine3 device verses conventional sutures

Device: conventional Suture

Zip3 Device

ACTIVE COMPARATOR
Device: Zip3

Interventions

Sutures

Also known as: stitches,PeriStrips
sutures
Zip3DEVICE

wound closure device

Zip3 Device

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients between 18 and 75 years of age
  • In generally good health
  • Willing to be evaluated in 5-14 days and 3-months post op
  • Patient requiring a non-emergent skin incision or biopsy
  • Maximum excision size 1.5x3.0 cm
  • Requiring 4-0 or smaller suture for closure
  • In area of body trunk or extremities with low mobility and tension

You may not qualify if:

  • Facial Incisions or incisions in high stress or tension areas
  • Previously diagnosed peripheral vascular disease
  • Insulin-dependent diabetes mellitus
  • Known bleeding diathesis
  • Known personal or family history of keloid formation or scar hypertrophy
  • Known allergy or hypersensitivity to adhesives
  • Presently taking steroids, immune stimulants, beta blockers, or anticoagulants
  • Atrophic skin deemed clinically prone to blistering
  • Any skin disorder affecting wound healing
  • Incisions requiring dermal sutures
  • Any other condition that in the opinion of the investigator would make a particular patient unsuitable for this study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Palo Alto Medical Foundation

Palo Alto, California, 94301, United States

Location

Plastic Surgery Institute of Northern California

San Francisco, California, 94114, United States

Location

California Pacific Medical Center

San Francisco, California, 94115, United States

Location

MeSH Terms

Conditions

Wounds and Injuries

Study Officials

  • Brian M Parret, MD

    Plastic Surgery Institute of Northern California

    PRINCIPAL INVESTIGATOR
  • Landon Clark, MD,MPH

    Palo Alto Medical Foundation

    PRINCIPAL INVESTIGATOR
  • Stanley P Leong, MD,FACS

    California Pacific Medical Center

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 21, 2012

First Posted

June 28, 2017

Study Start

October 1, 2012

Primary Completion

October 1, 2012

Study Completion

October 1, 2012

Last Updated

June 28, 2017

Record last verified: 2017-06

Locations