NCT03201172

Brief Summary

The study is designed as a monocentric, prospective, observational, comparative follow-up study based on two previously treated patient groups. The first group consists of patients treated with the patient-specific unicondylar knee implant iUni®. For that group, 30 patients will be included in the study and analyzed. The final follow-up after 24 months has already been documented by the study center. Compared to that, a consecutive series of 50 Univation® X patients will be invited for a 24 months follow-up in 2018. In total, it is planned to include 80 retrospective patients for that historical control study design. The products under investigation were used in routine clinical practice and according to the authorized Instructions for Use (IfU). Those data that are obtained in routine clinical use will be documented in the Case Report Form (CRF).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
77

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Sep 2017

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 23, 2017

Completed
1 month until next milestone

First Posted

Study publicly available on registry

June 28, 2017

Completed
3 months until next milestone

Study Start

First participant enrolled

September 25, 2017

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 30, 2019

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2020

Completed
Last Updated

April 15, 2021

Status Verified

April 1, 2021

Enrollment Period

2 years

First QC Date

May 23, 2017

Last Update Submit

April 14, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Knee joint function

    Knee Society Score

    2 years after primary implantation

Secondary Outcomes (4)

  • KOOS

    2 years after primary implantation

  • axis justice position

    preoperative and until discharge from hospital (within 1 week postoperatively)

  • radiolucent lines

    2 years after primary implantation

  • tibial slope

    2 years after primary implantation

Other Outcomes (1)

  • Adverse Events

    2 years after primary implantation

Study Arms (2)

Univation® X

Device: Primary Unicompartmental Knee Arthroplasty

iUni®

Device: Primary Unicompartmental Knee Arthroplasty

Interventions

Primary implantation of an unicompartmental knee implant

Univation® XiUni®

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

adult patients

You may qualify if:

  • Patients who underwent UKA in 2015/2016 (using one of the products under investigation)
  • Signed informed consent

You may not qualify if:

  • pregnancy
  • patients \< 18 years

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

St. Vincenz Hospital Brakel

Brakel, 33034, Germany

Location

Related Publications (1)

  • Haaker R, Moussa A, Sabev D. No advantage for patient-specific UKA in comparison with standard UKA regarding clinical and functional results at short-term follow-up. Eur J Orthop Surg Traumatol. 2025 Aug 27;35(1):362. doi: 10.1007/s00590-025-04467-2.

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 23, 2017

First Posted

June 28, 2017

Study Start

September 25, 2017

Primary Completion

September 30, 2019

Study Completion

April 1, 2020

Last Updated

April 15, 2021

Record last verified: 2021-04

Data Sharing

IPD Sharing
Will not share

Locations