NCT04199481

Brief Summary

The study is set up due to regulatory purposes and to collect routine clinical data of the mobile-bearing implant univation XM. The study is designed as a prospective follow-up study with a historic patient cohort who have been treated with the product under investigation two years ago. This design is selected to quicker realize follow-up data as patients have already been treated in the past. As the mobile version of the implant is not widely used, the study will be set up as a monocentric study in France. The clinical hypothesis of the study is that patients who are treated with the product under investigation have a similar outcome and survival rate in comparison to other established unicondylar knee systems on the market. Comparison for the later evaluation will be taken out of recent orthopaedic registries.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Aug 2020

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 12, 2019

Completed
4 days until next milestone

First Posted

Study publicly available on registry

December 16, 2019

Completed
8 months until next milestone

Study Start

First participant enrolled

August 1, 2020

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2023

Completed
Last Updated

July 23, 2020

Status Verified

July 1, 2020

Enrollment Period

3 years

First QC Date

December 12, 2019

Last Update Submit

July 21, 2020

Conditions

Keywords

unicompartmental knee arthroplastyretrospective studyKnee Society Score

Outcome Measures

Primary Outcomes (1)

  • Survival Rate of the Implant

    Revision-free survival rate after 5 years according to Kaplan-Meier

    5 years after surgery

Secondary Outcomes (5)

  • Development of Knee joint function

    in the postoperative course, up to 5 years after surgery

  • Development of Oxford Knee Score

    in the postoperative course, up to 5 years after surgery

  • Intraoperative/surgery Data

    intraoperative

  • Radiographic evaluation

    in the postoperative course, up to 5 years after surgery

  • Rate of Serious Adverse Events

    in the postoperative course, up to 5 years after surgery

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

adult patients

You may qualify if:

  • Patient has received a primary mobile bearing UKA at the study site between January 2017 and December 2018 using the product under investigation
  • Patient's written consent and willingness to participate at the clinical study and the follow-up examinations

You may not qualify if:

  • Pregnancy
  • Patient Age \<18 years at the time of the surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHU Hopital Hautepierre

Strasbourg, 67098, France

Location

MeSH Terms

Conditions

Osteoarthritis, Knee

Condition Hierarchy (Ancestors)

OsteoarthritisArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic Diseases
0

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 12, 2019

First Posted

December 16, 2019

Study Start

August 1, 2020

Primary Completion

August 1, 2023

Study Completion

August 1, 2023

Last Updated

July 23, 2020

Record last verified: 2020-07

Locations