Mindfulness in Old Adults With Subjective Cognitive Complaints

NCT03195985 | Completed

• 1 other identifier: C&W1234
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 2

Brief Summary

The study will focus on measuring stress, rumination and cognitive function across three time points in old adults with subjective cognitive complaints via a 4-week short mindfulness intervention, as compare to an active control condition (psycho-education course "ge Well"). This is a pilot study.

Conditions

Subjective Cognitive Complaints; Mindfulness

Outcome Measures

Primary Outcomes (1)

• Changes in cortisol levels between the two MCI groups over time

  assessed by collecting hair from the vertex posterior for stress hormone analysis

  One month

Secondary Outcomes (2)

• Changes in anxiety over time

  One month

• Changes in verbal learning and memory over time

  One month

Study Arms (2)

Mindfulness-based Intervention

EXPERIMENTAL

Mindfulness intervention of 4 weeks

Other: Mindfulness-based intervention

"Age Well" psycho-education course

ACTIVE COMPARATOR

4-week active control condition

Other: Age Well psycho-education

Interventions

Mindfulness-based intervention OTHER

A shortened, 4 week mindfulness intervention course based on the original 8 week mindfulness-based stress reduction course by Jon Kabat-Zinn

Mindfulness-based Intervention

Age Well psycho-education OTHER

4-week active control condition aimed at psycho-education regarding healthy ageing

"Age Well" psycho-education course

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)

You may qualify if:

• All willing and consenting patients over the age of 65
• Patients who have been admitted to the hospital and who have been formally diagnosed with MCI at the Memory Clinic
• Patients with hair at the posterior vertex
• Patients with fluent English
• Patients who can commit to the entire length of the study
• Patients with interest in mindfulness

You may not qualify if:

• Being under 65 years of age
• Presence of any psychiatric disorders,
• Presence of myopathy
• Presence of atherosclerosis
• Use of steroids
• Having undergone chemotherapy
• heart disorder
• dementia
• head injury
• advanced neurodegenerative disease
• any patient having had dyed their hair less than one week prior to the first cortisol sampling

Sponsors & Collaborators

• Chelsea and Westminster NHS Foundation Trust: lead
• University of Westminster: collaborator
• Imperial College London: collaborator

Study Sites (2)

Chelsea and Westminster Hospital NHS Trust

London, sw10 9nh, United Kingdom

Location

The Magill Department of Anaesthesia, Chelsea and Westminster Hospital

London, SW10 9NH, United Kingdom

Location

Study Officials

• Trudi Edginton, PhD

  Chelsea & Westminster Hospital, London UK

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Consultant in Anaesthesia and Intensive Care

Study Record Dates

• First Submitted: December 2, 2016
• First Posted: June 22, 2017
• Study Start: July 1, 2017
• Primary Completion: December 1, 2017
• Study Completion: February 1, 2018
• Last Updated: March 13, 2018

Record last verified: 2018-03

Data Sharing

• IPD Sharing: Will not share

Locations

GB (2)