NCT03194412

Brief Summary

This intervention study is a part of the FOCUS (Frailty Management Optimization Through EIP AHA Commitments and Utilization of Stakeholders Input) project which purpose is to critically reduce the burden of frailty in Europe by assisting those partners within the European Innovation Partnership for Active Healthy Ageing (EIPAHA) with commitments focusing on early diagnosis/ screening and/or management of frailty to achieve scalability. FOCUS aims to critically reduce the burden of frailty in Europe by developing methodologies and tools to assist entities focusing on early diagnosis, screening and management of frailty to achieve scalability. Frailty is a common clinical syndrome in older adults that brings an increased risk for poor health outcomes including falls, incident disability, hospitalization and mortality. The FOCUS Consortium brings together a multidisciplinary team of specialists from 10 organizations in 6 countries - Italy, Poland, Portugal, Spain, Netherlands, United Kingdom - that will work on developing, piloting and disseminating methodologies and tools to assist entities focusing on early diagnosis, screening and management of frailty to achieve scalability. Wroclaw Medical University actively participates in all projects for the advances in science, entrepreneurship, technological innovation, both with public authorities, local governments, and enterprises. In FOCUS project, WMU is responsible for Evaluation of the project and collaborates with the others partners in Coordination of the project, Dissemination of the project, Synthesis of learning and realities of practice, Analysis and guidelines development, Creation of Network and Platform for knowledge exchange, Test of guidelines in a set of commitments (Work Package 7 - WP7). The outcomes of this proposal will offer significant potential improvements for innovative, coordinated and comprehensive community based prevention with regard to the optimisation of functional capacity tools to address pre-frailty, and for improving the management of frailty. The registered study has its own protocol developed by Wroclaw Medical University research team and will be implemented within WP7 of the FOCUS project.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
210

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started May 2017

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 19, 2017

Completed
29 days until next milestone

First Submitted

Initial submission to the registry

June 17, 2017

Completed
4 days until next milestone

First Posted

Study publicly available on registry

June 21, 2017

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 30, 2017

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2017

Completed
Last Updated

November 1, 2017

Status Verified

October 1, 2017

Enrollment Period

4 months

First QC Date

June 17, 2017

Last Update Submit

October 31, 2017

Conditions

Keywords

Frail ElderlyGeriatric AssessmentHumansAged

Outcome Measures

Primary Outcomes (1)

  • Functional status change

    People who improved/worsened functional status according to standardized measures

    6 months

Secondary Outcomes (4)

  • Falls change

    6 months

  • Mood change

    6 months

  • Nutritional status change

    6 months

  • Cognitive status change

    6 months

Study Arms (5)

Diet /nutritional

EXPERIMENTAL

Special diet for elderly. It should be rich in the appropriately amount of protein, carotenoids, vitamins, minerals, macro and micronutrients.

Dietary Supplement: Diet /nutritional

Physical activity

EXPERIMENTAL

Regular physical activity in everyday life of the elderly - exercises to improve coordination and balance, stretching exercises, strength exercises.

Behavioral: Physical activity

Comprehensive therapy

EXPERIMENTAL

Special diet for elderly (appropriately amount of protein, carotenoids, vitamins, minerals, macro and micronutrients) and regular physical activity in everyday life of the elderly (exercises to improve coordination and balance, stretching exercises, strength exercises)

Combination Product: Comprehensive therapy

Caregivers of elderly

EXPERIMENTAL

Education about frailty: prevention and treatment (nutrition, physical activity, dietary supplement diet).

Behavioral: Caregivers of elderly

Control group

NO INTERVENTION

Without intervention

Interventions

Diet /nutritionalDIETARY_SUPPLEMENT

• Duration: * the first stage - 3 months: 12 weeks * second stage - 3 months: 12 weeks Each patient collect a detailed menu of the last two days before making the description. Then the menu is analyzed by a nutrition consultant. The role of nutrition consultant is: * make a diet modification to include the products recommended in frailty * modifying eating habits The diet modification is mainly focused on adequate supply: * vitamin D (according to Central Europe guidelines -2013 for seniors) * protein (according to European Society for Clinical Nutrition and Metabolism (ESPEN recommendations)

Diet /nutritional

* Duration: * the first stage - 3 months: 12 weeks * second stage - 3 months: 12 weeks * Frequency: twice a week * Duration of each session: 60 minutes Worksheets for the elderly with frailty syndrome have been developed: * resistance exercises and strength training, which aim to improve muscle strength in the limbs * exercises aimed at improving motor coordination, flexibility and speed * stretching exercises.

Also known as: regular physical activity in everyday life of the elderly
Physical activity
Comprehensive therapyCOMBINATION_PRODUCT

Combination of special diet for elderly (as in Group 1) and regular physical activity into everyday life of the elderly (as in Group 2) Duration: * the first stage - 3 months- 12 weeks * the second stage - 3 months- 12 weeks Frequency of physical activity: twice a week Duration of each session: 60 minutes

Also known as: diet/nutritional and physical activity training
Comprehensive therapy

Group: formal and informal caregivers of elderly with frailty syndrome Materials and Tools: multimedia presentation about frailty prevention and treatment (nutrition, physical activity, dietary supplement diet). Duration: * the first stage - 3 months: 12 weeks * the second stage - 3 months: 12 weeks Frequency: 1 (at the beginning of stage 0, 1 and 2) Duration: 60 minutes

Caregivers of elderly

Eligibility Criteria

Age60 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • patients:
  • age ≥ 60 years old
  • recognition of the pre-frail and frail (based on the scale of the Cardiovascular Health Study)
  • consent to participate in the study
  • the patients who could speaking Polish language
  • caregivers:
  • to be formal or informal caregivers of person aged ≥ 60 years old
  • consent to participate in the study
  • caregivers who could speaking Polish language

You may not qualify if:

  • patients:
  • age \< 60 years old
  • lack of recognition of the pre-frail and frail (based on the scale of the Cardiovascular Health Study)
  • somatic state which precludes complete examination performance according to selected scales (eg. Vision disorders)
  • severe mental disorders or difficulties that prevent active participation in the study
  • the patients who could not speaking Polish language
  • lack of consent to participate in the study
  • caregivers:
  • not to be formal or informal caregivers of person aged ≥ 60 years old
  • lack of consent to participate in the study
  • the caregivers who could not speaking Polish language

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Wroclaw Medical University

Wroclaw, Wroclaw, 50-345, Poland

Location

Related Publications (2)

  • Antonio Cano, Donata Kurpas, Maria Magdalena Bujnowska-Fedak, Silvina Santana, Carol Holland, Maura Marcucci, Ana Gonzalez- Segura, Miriam Vollenbroek-Hutten, Barbara D'Avanzo, Alessandro Nobili, João Luís Al ves Apostolo, Elżbieta Bobrowicz-Campos, Ana M. Martínez-Arroyo. FOCUS: Frailty Management Optimisation through EIPAHA Commitments and Utilisation of Stakeholders' Input - an innovative European Project in elderly care. Family Medicine & Primary Care Review 2016; 18, 3: 373-376 DOI: https://doi.org/10.5114/fmpcr/63234

    BACKGROUND
  • Piotrowicz J, Soll A, Kielar U, Zwiefka A, Guligowska A, Pigłowska M, Kostka T, Kurpas D. ICT and environmental support for patients with frailty syndrome: CareWell Project, Focus Project and SUNFRAIL Project. Medical Science Pulse 2017; 11, 1: 37-43.

    BACKGROUND

Related Links

MeSH Terms

Conditions

Frailty

Interventions

DietExercise

Condition Hierarchy (Ancestors)

Pathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Nutritional Physiological PhenomenaDiet, Food, and NutritionPhysiological PhenomenaMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Aneta Soll, MSc

    Wroclaw Medical University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
FACTORIAL
Model Details: The group of participants involved to the study: * n=60 ( at least 30) to diet /nutritional - intervention group 1 * n=60 ( at least 30) to physical activity - intervention group 2 * n=60 ( at least 30) to comprehensive therapy (diet/nutritional+physical activity training) - intervention group 3 * n=30 (at least 15) formal and informal caregivers of elderly - intervention group 4 * n=60 ( at least 30) to control group without intervention - group 5 Evaluation process: * Screening Evaluation (stage 1)- investigated within 0 * Baseline Evaluation (stage 2) - after 3 months from 0 * Final Evaluation (stage 3) - after 6 months from 0 Professionals involved in the interventions: physicians, general practitioners, physiotherapists, rehabilitation professionals, educators, nurses, volunteers, nutrition consultant.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Donata Kurpas, MD, PhD, Assoc. Prof.

Study Record Dates

First Submitted

June 17, 2017

First Posted

June 21, 2017

Study Start

May 19, 2017

Primary Completion

September 30, 2017

Study Completion

December 1, 2017

Last Updated

November 1, 2017

Record last verified: 2017-10

Data Sharing

IPD Sharing
Will not share

Locations