The Effect of Walking on Frailty

NCT03654807 | Completed

• 1 other identifier: STU00207757
• Study Type: interventional
• Target: 156
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to test the effect of walking intensity on both frailty category (i.e., frail, pre-frail, and nonfrail) and frailty score as a continuous outcome on the SHARE-FI (frailty instrument). As well as test the effect of walking intensity on mobility, physical function, balance, and total Physical Activity.

Conditions

Frailty

Outcome Measures

Primary Outcomes (1)

• Change in frailty as measured by the Survey of Health, Ageing, and Retirement in Europe-Frailty Instrument (SHARE-FI)

  SHARE-FI which assesses fatigue, appetite, weakness, walking difficulties, and low physical activity

  Baseline and four months

Secondary Outcomes (7)

• Improved mobility as measured by gait speed

  Baseline and four months

• Improved physical function on the Short Physical Performance Battery

  Baseline and four months

• Improved balance as measured by the Berg Balance Scale

  Baseline and four months

• Total daily physical activity

  Baseline and Four Months

• Improved mobility as measured by Time Up and Go

  Baseline and Four Months

Study Arms (2)

High Intensity Walking

EXPERIMENTAL

HIW (70-80% HRmax)

Behavioral: High Intensity Walking

Casual Speed Walking

EXPERIMENTAL

Self selected pace

Behavioral: Casual Speed Walking

Interventions

High Intensity Walking BEHAVIORAL

70-80% HRmax

High Intensity Walking

Casual Speed Walking BEHAVIORAL

Self selected pace

Casual Speed Walking

Eligibility Criteria

• Age: 60 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• \> 60 years of age with pre-frailty or frailty as determined on the SHARE-FI.
• Able to ambulate at least 10 feet with moderate assistance (\<50% physical assistance) or less. Participants will be able to use their assistive device (e.g. cane or walker) during sessions.
• Resident of one of the 10 enrolled retirement community locations. Individuals must be \> 60 years of age to move into the retirement communities by virtue of the individual community policies.
• Provision of informed consent and clearance for participation as determined by the Exercise and Screening for You (EASY).

You may not qualify if:

• Uncontrolled cardiovascular, metabolic, renal, or respiratory disease that limits exercise participation (e.g., previous heart attack within 3 months of enrollment or uncontrolled diabetes)
• Resting blood pressure \> 180/110 mmHg.

Sponsors & Collaborators

• Northwestern University: lead

Study Sites (1)

Northwestern Univiersity Department of Physical Therapy and Human Movement Sciences

Chicago, Illinois, 60611, United States

Location

Related Publications (1)

• Davila VS, Conroy DE, Danilovich MK. Factors That Influence Walking Intervention Adherence for Older Adults Living in Retirement Communities. J Aging Phys Act. 2022 Feb 1;30(1):65-72. doi: 10.1123/japa.2020-0279. Epub 2021 Aug 12.

  PMID: 34384049 DERIVED

MeSH Terms

Conditions

Frailty

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Margaret Danilovich, PhD

  Northwestern University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: August 21, 2018
• First Posted: August 31, 2018
• Study Start: November 26, 2018
• Primary Completion: January 31, 2023
• Study Completion: May 31, 2024
• Last Updated: August 22, 2024

Record last verified: 2024-08

Locations

US (1)