Study Stopped
PI left institution
Multi-parametric Magnetic Resonance Imaging for Prostate Cancer Patients
Pilot Study of Using Multi-parametric Magnetic Resonance Imaging for Organ Delineation and Tumor Response Assessment of Prostate Cancer Patients Being Treated With Radiation Therapy
1 other identifier
interventional
9
1 country
1
Brief Summary
This is a pilot study of implement multi-parametric MR imaging for organ delineation and tumor response assessment of prostate cancer patients being treated with radiation therapy.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable prostate-cancer
Started Oct 2017
Typical duration for not_applicable prostate-cancer
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
June 5, 2017
CompletedFirst Posted
Study publicly available on registry
June 8, 2017
CompletedStudy Start
First participant enrolled
October 4, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 15, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
February 15, 2022
CompletedResults Posted
Study results publicly available
October 12, 2023
CompletedOctober 12, 2023
September 1, 2023
4.4 years
June 5, 2017
March 20, 2023
September 21, 2023
Conditions
Outcome Measures
Primary Outcomes (2)
Detection of Imaging Biomarkers to Localize the Intraprostatic Lesions and Predict Radiation Treatment Response
Identify the radiomics features selected from multimodal MRI to distinguish the dominant lesions from the normal tissues within the prostate. Track the changes of these features with longitudinal MRI scans to identify its correlation with the local control.
2 years
Tumor Response
Tumor response as measured by an increase in PSA.
2 years
Study Arms (1)
Multi-parametric MRI for Prostate Cancer
EXPERIMENTALMRI will be acquired for prostate cancer patients undergoing radiation treatment.
Interventions
MRI will be acquired before, during and after radiation treatment to evaluate treatment response
Eligibility Criteria
You may qualify if:
- Histologically confirmed prostate adenocarcinoma
You may not qualify if:
- Patients with metal fragments or implanted devices such as pacemakers and aneurysm clips are not eligible for the study considering
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Henry Ford Health System
Detroit, Michigan, 48202, United States
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Results Point of Contact
- Title
- Dr. Stephen Brown
- Organization
- Henry Ford Health
Publication Agreements
- PI is Sponsor Employee
- Yes
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Director, Radiobiology Research Laboratories
Study Record Dates
First Submitted
June 5, 2017
First Posted
June 8, 2017
Study Start
October 4, 2017
Primary Completion
February 15, 2022
Study Completion
February 15, 2022
Last Updated
October 12, 2023
Results First Posted
October 12, 2023
Record last verified: 2023-09