"Ounce-equivalents" in the Protein Foods Group: Benefits of Quality

NCT03179462 | Completed Results

• 1 other identifier: 206579
• Study Type: interventional
• Target: 27
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators will examine the effects of a given amount of a protein food source such as pork, mixed nuts, and tofu on anabolic response at the whole body and muscle levels in young, healthy adults.

Conditions

Protein Metabolism

Outcome Measures

Primary Outcomes (1)

• Net Protein Synthesis Rate

  Net protein synthesis rate is determined in the 4.5-hours basal fasted period and 4-hours post-meal period over the 8.5-hour experimental period.

  Change from 4.5 to 8.5 hours.

Study Arms (3)

Pork intake

EXPERIMENTAL

Subjects will consume 2 ounces of cooked lean pork following diet normalization for 3 days.

Dietary Supplement: Pork intake

Mixed nuts intake

EXPERIMENTAL

Subjects will consume 1 ounce of mixed nuts following diet normalization for 3 days.

Dietary Supplement: Mixed nuts intake

Tofu intake

EXPERIMENTAL

Subjects will consume 2 ounces of tofu following diet normalization for 3 days.

Dietary Supplement: Tofu intake

Interventions

Pork intake DIETARY_SUPPLEMENT

Each participant will consume 2 ounces of cooked lean pork.

Pork intake

Mixed nuts intake DIETARY_SUPPLEMENT

Each participant will consume 1 ounce of mixed nuts.

Mixed nuts intake

Tofu intake DIETARY_SUPPLEMENT

Each participant will consume 2 ounces of tofu.

Tofu intake

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Men and women, ages 18-40 years
• BMI from 20 to 29.9 kg/m2

You may not qualify if:

• Current diagnosis of diabetes
• History of malignancy in the 6 months prior to enrollment
• History of a chronic inflammatory condition or other chronic diseases (Lupus, HIV/AIDS, etc)
• History of weight reduction surgery (Lapband, gastric sleeve, etc.)
• Pregnant females
• Subjects who do not or will not eat animal proteins
• Subjects allergic to pork, tree or peanuts, or soybeans
• Subjects who cannot refrain from consuming protein or amino acid supplements during their participation in this study
• Subjects who report regular resistance training exercise \> one per week
• Hemoglobin \< 9.5 g/dL at the screening visit
• Platelets \< 250,000 at the screening visit
• Concomitant use of corticosteroids (ingestion, injection or transdermal)
• Any other disease or condition that would place the subject at increased risk of harm if they were to participate, at the discretion of the study physician

Sponsors & Collaborators

• University of Arkansas: lead

Study Sites (1)

University of Arkansas for Medical Sciences

Little Rock, Arkansas, 72202, United States

Location

Results Point of Contact

• Title: David D.Church, Ph.D.
• Organization: University of Arkansas for Medical Sciences

dchurch@uams.edu

5015265709

Publication Agreements

• PI is Sponsor Employee: Yes
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 5, 2017
• First Posted: June 7, 2017
• Study Start: December 1, 2017
• Primary Completion: June 6, 2018
• Study Completion: July 1, 2019
• Last Updated: December 6, 2021
• Results First Posted: September 30, 2021

Record last verified: 2021-10

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)