Are the "ounce-equivalents" in the Protein Foods Groups Really Equivalent?

NCT03142737 | Completed

• 1 other identifier: 205366
• Study Type: interventional
• Target: 45
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators will determine effects of different sources of protein on whole-body net protein synthesis and muscle protein synthesis in young healthy participants.

Conditions

Protein Metabolism

Outcome Measures

Primary Outcomes (1)

• Net protein synthesis rate

  Net protein synthesis rate is determined in the 4.5-hour basal fasted period and 4-hous post-meal period over the 8.5-hour experimental period

  Up to 8.5 hours

Study Arms (5)

Red kidney bean intake

EXPERIMENTAL

Subjects will consume 1/2 cup of cooked red kidney bean following diet normalization for 3 days.

Other: Red kidney bean intake

Eggs intake

EXPERIMENTAL

Subjects will consume 2 cooked large eggs following diet normalization for 3 days.

Other: Eggs intake

Peanut butter intake

EXPERIMENTAL

Subjects will consume 2 tablespoons of peanut butter following diet normalization for 3 days.

Other: Peanut butter intake

Ground beef intake

EXPERIMENTAL

Subjects will consume 2 ounces of 90% lean ground beef following diet normalization for 3 days.

Other: Ground beef intake

Intact beef intake

EXPERIMENTAL

Subjects will consume 2 ounces of intact beef following diet normalization for 3 days.

Other: Intact beef intake

Interventions

Red kidney bean intake OTHER

Each participant will consume 1/2 cup of cooked red kidney bean

Red kidney bean intake

Eggs intake OTHER

Each participant will consume 2 cooked large eggs.

Eggs intake

Peanut butter intake OTHER

Each participant will consume 2 tablespoons of peanut butter.

Peanut butter intake

Ground beef intake OTHER

Each participant will consume 2 ounces of 90% lean ground beef.

Ground beef intake

Intact beef intake OTHER

Each participant will consume 2 ounces of intact beef.

Intact beef intake

Eligibility Criteria

• Age: 20 Years - 40 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Men and women, ages 20-40 years
• BMI from 20 to 29.9 kg/m2

You may not qualify if:

• Current diagnosis of diabetes
• History of malignancy in the 6 months prior to enrollment
• History of gastrointestinal bypass surgery
• History of a chronic inflammatory condition or other chronic diseases (Lupus, HIV/AIDS, etc)
• Female subjects who are currently pregnant
• Subjects who are unable to eat animal protein
• Subjects who are unable to stop eating protein or Amino Acid (AA) supplements during the participation
• Subjects who report regular resistance training (more than twice per week)
• Subjects who have concomitant use of corticosteroids (ingestion, injection or transdermal)
• Hemoglobin less than 9.5 g/dL at the screening visit
• Platelets less than 250,000 at the screening visit.
• Any other disease or condition that would place the subject at increased risk of harm if they were to participate, at the discretion of the study physician

Sponsors & Collaborators

• University of Arkansas: lead

Study Sites (1)

University of Arkansas for Medical Sciences

Little Rock, Arkansas, 72202, United States

Location

Study Officials

• Robert Wolfe, PhD

  University of Arkansas

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 2, 2017
• First Posted: May 5, 2017
• Study Start: May 8, 2017
• Primary Completion: March 6, 2018
• Study Completion: May 15, 2019
• Last Updated: September 3, 2024

Record last verified: 2019-06

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)