NCT03141788

Brief Summary

The objective of this study is to evaluate the efficacy of Clear Aligners to correct tooth malocclusions with the use of attachments and/or buttons, as determined by the amount of teeth movement and overall achievement goals of the treatment plan.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
52

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2017

Typical duration for not_applicable

Geographic Reach
1 country

9 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 30, 2017

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

April 27, 2017

Completed
8 days until next milestone

First Posted

Study publicly available on registry

May 5, 2017

Completed
2.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 9, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 9, 2019

Completed
1.1 years until next milestone

Results Posted

Study results publicly available

November 4, 2020

Completed
Last Updated

December 2, 2024

Status Verified

November 1, 2024

Enrollment Period

2.7 years

First QC Date

April 27, 2017

Results QC Date

September 14, 2020

Last Update Submit

November 27, 2024

Conditions

Keywords

Aligners

Outcome Measures

Primary Outcomes (1)

  • Successful Correction of Malocclusion

    Achievement of target setup per treatment plan as determined by Orthodontist.

    The expected duration of subject participation was to be 6 to 24 months. Due to additional time needed for orthodontic refinements, the actual longest duration was approximately 28 months.

Secondary Outcomes (11)

  • Individual Tooth Movement

    The expected duration of subject participation was to be 6 to 24 months. Due to additional time needed for orthodontic refinements, the actual longest duration was approximately 28 months.

  • Treatment Time for Tooth Movement

    The expected duration of subject participation was to be 6 to 24 months. Due to additional time needed for orthodontic refinements, the actual longest duration was approximately 28 months.

  • Effective Use of Attachments

    The expected duration of subject participation was to be 6 to 24 months. Due to additional time needed for orthodontic refinements, the actual longest duration was approximately 28 months.

  • Orthodontist Satisfaction

    The expected duration of subject participation was to be 6 to 24 months. Due to additional time needed for orthodontic refinements, the actual longest duration was approximately 28 months.

  • Software Satisfaction

    The expected duration of subject participation was to be 6 to 24 months. Due to additional time needed for orthodontic refinements, the actual longest duration was approximately 28 months.

  • +6 more secondary outcomes

Study Arms (1)

3M Clear Aligner

OTHER

Clear Aligner for Orthodontic Treatment

Device: Clear Aligner

Interventions

Clear Aligner used to straighten teeth to desired outcome

Also known as: 3M Clear Aligner
3M Clear Aligner

Eligibility Criteria

Age14 Years+
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Subject is at least 14 years of age.
  • Subject is willing and able to give informed consent.
  • Subject is willing to be digitally scanned at each 6-week visit, including after application of attachments.
  • Subject has a need for single or double arch orthodontic treatment with a target duration of 18 months or less.
  • Subject has good oral hygiene defined by the orthodontist.
  • Subject has only permanent dentition.

You may not qualify if:

  • Subject has skeletal discrepancies requiring surgery
  • Subject is undergoing active dental work
  • Subject has severe open bite \> 2 mm
  • Subject has severe overjet \> 4 mm
  • Subject has deep bite \> 3 mm
  • Subject has over crowding per arch \> 4 mm
  • Subject has dental prostheses/implants that will interfere with projected teeth movement
  • Subject is taking systemic steroid medication
  • Subject is taking Biphosphonates or any other medication for treatment of osteoporosis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (9)

Benson Orthodontics

Denver, Colorado, 80209-3244, United States

Location

Depew Orthodontics

Kennesaw, Georgia, 30144, United States

Location

Orthodontics Associates

Catonsville, Maryland, 21228, United States

Location

Henseler Orthodontics

Woodbury, Minnesota, 55125, United States

Location

Horton Orthodontics

Woodbury, Minnesota, 55125, United States

Location

Mellion Orthodontics

Fairlawn, Ohio, 44333, United States

Location

Wolf/Chhibber Orthodontics

Norwalk, Ohio, 44857, United States

Location

Simply Smiles Orthodontics

McKinney, Texas, 75070, United States

Location

Riolo Orthodontics

Seattle, Washington, 98101, United States

Location

MeSH Terms

Conditions

Malocclusion

Interventions

Orthodontic Appliances, Removable

Condition Hierarchy (Ancestors)

Tooth DiseasesStomatognathic Diseases

Intervention Hierarchy (Ancestors)

Orthodontic AppliancesOrthodonticsDentistry

Results Point of Contact

Title
Elaine Egging
Organization
3M

Study Officials

  • Gail E Maxey, BA, CCRA

    3M Company

    STUDY DIRECTOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 27, 2017

First Posted

May 5, 2017

Study Start

January 30, 2017

Primary Completion

October 9, 2019

Study Completion

October 9, 2019

Last Updated

December 2, 2024

Results First Posted

November 4, 2020

Record last verified: 2024-11

Data Sharing

IPD Sharing
Will not share

Locations