Investigating Accelerated Learning in Healthy Subjects: Trigeminal Nerve Stimulation

NCT03138590 | Terminated Results FDA Device

• 1 other identifier: 17-34 TN
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to investigate whether it is possible to accelerate learning and improve associative memory performance in healthy subjects, by applying transcranial Direct Current Stimulation (tDCS) targeting the trigeminal nerve during a verbal paired-associate learning task

Conditions

Healthy Adults

Keywords

transcranial Direct Current Stimulation (tDCS); accelerate learning; memory

Outcome Measures

Primary Outcomes (1)

• Associative Memory Assessed by a Verbal Paired-Associate Test

  Changes in performance in the Verbal Paired-Associate memory task is compared between the 2 groups (1. Active tDCS 2. Sham tDCS) to investigate the influence of tDCS on Associative Memory.

  1 week after stimualtion

Study Arms (2)

Active tDCS

EXPERIMENTAL

Active transcranial Direct Current Stimulation targeting the trigeminal nerve

Device: Transcranial Direct Current Stimulation- Neuroconn DC Stimulator PLUS

Sham tDCS

SHAM COMPARATOR

Sham transcranial Direct Current Stimulation targeting the trigeminal nerve

Device: Transcranial Direct Current Stimulation- Neuroconn DC Stimulator PLUS

Interventions

Transcranial Direct Current Stimulation- Neuroconn DC Stimulator PLUS DEVICE

Transcranial Direct Current Stimulation targeting the trigeminal nerve

Active tDCS; Sham tDCS

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Native English Speaker

You may not qualify if:

• History of severe head injuries, epileptic insults, or heart disease.
• Severe psychiatric disorders and severe untreated medical problems
• Acquainted with the foreign language used in the learning task
• Contraindications for tDCS (e.g. pregnant, implanted devices)

Sponsors & Collaborators

• The University of Texas at Dallas: lead

Study Sites (1)

The University of Texas of Dallas

Richardson, Texas, 75080, United States

Location

Results Point of Contact

• Title: Dr. Sven Vanneste, Principal Investigator
• Organization: University of Texas at Dallas

sven.vanneste@utdallas.edu

972-883-7277

Study Officials

• Sven Vanneste

  The University of Texas at Dallas

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate professor

Model Details: participants will be randomly assigned to one of 2 groups: (1) active tDCS (2) sham tDCS

Study Record Dates

• First Submitted: April 28, 2017
• First Posted: May 3, 2017
• Study Start: April 4, 2017
• Primary Completion: January 25, 2022
• Study Completion: January 25, 2022
• Last Updated: February 3, 2022
• Results First Posted: September 11, 2020

Record last verified: 2022-01

Locations

US (1)