NCT03137732

Brief Summary

This is a single centred randomized controlled trial comparing surgeon versus anaesthetist inserted rectus sheath catheters for management of analgesia post major abdominal surgery.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jun 2017

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 26, 2017

Completed
7 days until next milestone

First Posted

Study publicly available on registry

May 3, 2017

Completed
29 days until next milestone

Study Start

First participant enrolled

June 1, 2017

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2017

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2018

Completed
Last Updated

May 3, 2017

Status Verified

April 1, 2017

Enrollment Period

6 months

First QC Date

April 26, 2017

Last Update Submit

April 28, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Time taken to insert rectus sheath catheters

    This will be recorded in theatre on a stopwatch and recorded.

    under 15 minutes

Secondary Outcomes (6)

  • Pain scores

    4 days

  • Peri-operative analgesic use

    4 days

  • Catheter issues

    4 days

  • Duration of catheter use

    4 days

  • TIme to diet and mobilisation

    likely 1-3 days

  • +1 more secondary outcomes

Study Arms (2)

Surgeon-inserted

ACTIVE COMPARATOR

Rectus sheath catheter will be inserted under direct vision / palpation of the space at the end of the operation.

Device: Rectus Sheath Catheter

Anaesthetist-inserted

ACTIVE COMPARATOR

Rectus sheath catheter will be inserted under ultrasound guidance by the anaethetist.

Device: Rectus Sheath Catheter

Interventions

Insertion of rectus sheath catheter via either method

Anaesthetist-insertedSurgeon-inserted

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients aged over 18 years
  • Able to provide informed consent
  • Undergoing elective, open colorectal surgery or emergency laparotomy via a midline incision extending above the umbilicus
  • Weight of 50kg or over to standardise the analgesia given.

You may not qualify if:

  • Weight of less than 50kg
  • Patients unable to consent
  • Age under 18 years
  • Inability to insert RSC - local infection or severe coagulopathy
  • Allergy to local anaesthetic
  • Chronic pre-operative use of strong opioids or gabapentins and or chronic pain syndromes

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Pain, PostoperativeAbdominal InjuriesSurgical Wound

Condition Hierarchy (Ancestors)

Postoperative ComplicationsPathologic ProcessesPathological Conditions, Signs and SymptomsPainNeurologic ManifestationsSigns and SymptomsWounds and Injuries

Central Study Contacts

Dale Vimalachandran, MBChB MD FRCS

CONTACT

Elizabeth G Kane, MBChB BSc MRCS

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Masking Details
Patients will be blinded to the intervention that they are randomized to intraoperatively.
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Consultant Colorectal Surgeon

Study Record Dates

First Submitted

April 26, 2017

First Posted

May 3, 2017

Study Start

June 1, 2017

Primary Completion

December 1, 2017

Study Completion

June 1, 2018

Last Updated

May 3, 2017

Record last verified: 2017-04