NCT04755725

Brief Summary

One hundred and twenty patients at age range from 18 to 60 undergoing laparotomy was enrolled in this study. Patients were randomly assigned to two groups 60 in epidural group and the other 60 patients in rectus catheter group. epidural catheter inserted pre induction but rectus sheath catheter inserted by the surgeon at the end of surgery.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
120

participants targeted

Target at P75+ for not_applicable postoperative-pain

Timeline
Completed

Started Jan 2022

Typical duration for not_applicable postoperative-pain

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 3, 2021

Completed
13 days until next milestone

First Posted

Study publicly available on registry

February 16, 2021

Completed
11 months until next milestone

Study Start

First participant enrolled

January 10, 2022

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2023

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2023

Completed
Last Updated

December 19, 2023

Status Verified

December 1, 2023

Enrollment Period

1.7 years

First QC Date

February 3, 2021

Last Update Submit

December 18, 2023

Conditions

Keywords

rectus sheath catheter, pain following laparotomys.

Outcome Measures

Primary Outcomes (1)

  • Postoperative pain relief

    Measured by Visual Analogue Scale (VAS) pain measurement scale divided from 0 to 10 where 0 is no pain and10 worst pain can be imagined

    36hours

Secondary Outcomes (2)

  • Side effects

    36hours

  • Total of analgesic consumption

    36 hours

Study Arms (2)

Epidural Group

ACTIVE COMPARATOR

epidural catheter inserted pre induction

Device: Epidural catheter

Rectus sheath catheter Group

ACTIVE COMPARATOR

rectus sheath catheter inserted by the surgeon at the end of surgery

Device: rectus sheath catheter

Interventions

epidural catheter inserted pre induction

Epidural Group

The surgeon will place one hand inside the abdomen and with the other hand inserted the Tuohy needle through the skin and fascia. The surgeon will feel when the needle tip is just superfacial to interface between the peritoneum and muscle layer and avoid penetration of inferior epigastric artery. The procedure will be repeated on the contralateral

Rectus sheath catheter Group

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • patients at age rang from 18 to 60 undergoing laparotomy
  • patients ASA1,2 physical status

You may not qualify if:

  • any known coagulopathy
  • morbid obesity
  • kyphosis or scoliosis
  • those with known sensitivity to local anesthetic drugs
  • lack of cooperation and inability to understand or perform verbal or physical assessments.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Faculty of Medicine Menoufia University

Cairo, Governorate, 32511, Egypt

Location

Menoufia University

Cairo, Governorate, 32817, Egypt

Location

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative ComplicationsPathologic ProcessesPathological Conditions, Signs and SymptomsPainNeurologic ManifestationsSigns and Symptoms

Study Officials

  • Ahmed M Raouf, Professor

    Menoufia University

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
principal investigator

Study Record Dates

First Submitted

February 3, 2021

First Posted

February 16, 2021

Study Start

January 10, 2022

Primary Completion

October 1, 2023

Study Completion

November 1, 2023

Last Updated

December 19, 2023

Record last verified: 2023-12

Data Sharing

IPD Sharing
Will not share

Locations