Mechanical Ventilation Parameters in HAP Patients

NCT03111303 | Completed

• 1 other identifier: 65/16
• Study Type: observational
• Target: 2,654
• Locations: 0 countries
• Sites: N/A

Brief Summary

Hospital-acquired pneumonia (HAP) in patients in intensive care often requires the mechanical ventilation (MV). Management and weaning from MV are given by specificity of this type of pulmonary inflammation. Enrolled in the retrospective, observational study were all patients older than 18 years staying at the ICU of University Hospital in Olomouc, between 1 January 2011 and 31 December 2016. The determination of the parameters of the MV, ICU length of stay, hospital length of stay and mortality in HAP group were compared with the control group of patients without HAP.

Conditions

Mechanical Ventilation Pressure High

Outcome Measures

Primary Outcomes (1)

• length of mechanical ventilation

  days of MV

  during MV

Secondary Outcomes (3)

• ICU length of stay

  1 month

• Hospital length of stay (LOS)

  1 month

• Mortality

  1 month

Other Outcomes (2)

• Inspiratory pressure

  during MV

• Positive end expiratory pressure (PEEP)

  during MV

Study Arms (2)

HAP patients

Mechanical ventilation, patients fulfilled HAP criteria

Device: mechanical ventilation

non HAP patients

Mechanical ventilation, patients without HAP

Device: mechanical ventilation

Interventions

mechanical ventilation DEVICE

Connection to mechanical ventilator

HAP patients; non HAP patients

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Enrolled in the study were patients staying at the ICU of the Department of Anesthesiology and Intensive Care Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc and University Hospital Olomouc, between 1 January 2011 and 31 December 2015. The participants were all patients older than 18 years of age consecutively admitted to the ICU, who met HAP criteria.

You may qualify if:

• Age 18+
• Need of Mechanical ventilation (Pressure controlled mechanical ventilation or Pressure support ventilation)

You may not qualify if:

• Organ donor
• Need Volume controlled mechanical ventilation
• no mechanical ventilation

Sponsors & Collaborators

• University Hospital Olomouc: lead

MeSH Terms

Interventions

Respiration, Artificial

Intervention Hierarchy (Ancestors)

Airway Management; Therapeutics; Resuscitation; Emergency Treatment; Respiratory Therapy

Study Officials

• Radovan Uvizl

  UH Olomouc

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MD, Ph.D.

Study Record Dates

• First Submitted: April 7, 2017
• First Posted: April 12, 2017
• Study Start: January 1, 2011
• Primary Completion: December 31, 2016
• Study Completion: April 6, 2017
• Last Updated: October 26, 2017

Record last verified: 2017-10

Data Sharing

• IPD Sharing: Will not share