NCT03098966

Brief Summary

The purpose of the study to evaluate the practice and short term maternal and perinatal outcomes of trial of labor after cesarean section offered to women at Ain Shams University Maternity Hospital (ASUMH) during the 3-year period from January 2013 to December 2015.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
368

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2013

Typical duration for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2013

Completed
2.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2015

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2015

Completed
1.3 years until next milestone

First Submitted

Initial submission to the registry

March 28, 2017

Completed
7 days until next milestone

First Posted

Study publicly available on registry

April 4, 2017

Completed
10 months until next milestone

Results Posted

Study results publicly available

January 26, 2018

Completed
Last Updated

January 26, 2018

Status Verified

June 1, 2017

Enrollment Period

2.8 years

First QC Date

March 28, 2017

Results QC Date

April 4, 2017

Last Update Submit

June 16, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Number of Participants With Successful Vaginal Birth

    Mode of delivery: either successful vaginal birth after cesarean section or failed trial of labor (ending in emergency intrapartum cesarean section).

    24 hours after onset of trial of labor

Secondary Outcomes (2)

  • Number of Participants Who Had Maternal Morbidity

    48 hours after onset of trial of labor

  • Adverse Perinatal Outcomes

    48 hours postpartum

Eligibility Criteria

Age20 Years - 35 Years
Sexfemale
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

This is a retrospective study that was performed at Ain Shams University Maternity Hospital Records of hospital admissions during the planned time frame were reviewed. Subjects eligible for conduction of a Trial Of Labor After Cesarean section (TOLAC), were included, while those ineligible for TOLAC were excluded from the study dataset.

You may qualify if:

  • Women admitted in labour
  • One prior caesarean section
  • Singleton pregnancy
  • Vertex-presenting fetus

You may not qualify if:

  • Prior high-risk uterine scar; uterine rupture, classical CS, hysterotomy or myomectomy
  • Short inter-delivery interval (\<12 months)
  • Complications in the previous CS (e.g. puerperal sepsis)
  • Obstetric indication for CS (either elective or emergency):
  • Placenta praevia
  • Placental abruption
  • Documented evidence of cephalopelvic disproportion
  • Fetal macrosomia (estimated fetal weight \>4 kg)
  • Fetal anomalies interfering with vaginal delivery e.g. hydrocephalus
  • Fetal distress or non-reassuring Cardiotocography pattern

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Results Point of Contact

Title
Dr.Rehab Mohamed Abdelrahman
Organization
Ain Shams University

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Lecturer of Obstetrics and Gynaecology Faculty of Medicine, Ain Shams University

Study Record Dates

First Submitted

March 28, 2017

First Posted

April 4, 2017

Study Start

January 1, 2013

Primary Completion

November 1, 2015

Study Completion

December 1, 2015

Last Updated

January 26, 2018

Results First Posted

January 26, 2018

Record last verified: 2017-06

Data Sharing

IPD Sharing
Will not share