NCT03089827

Brief Summary

Participants enrolled at the Alzheimer's Disease Research Center (ADRC) at Wake Forest School of Medicine will be invited to take part in this study. The purpose of this study is to identify and measure the amount of a protein called amyloid in the brain.It is thought that the build up of amyloid may be related to the development of Alzheimer's disease.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
800

participants targeted

Target at P75+ for all trials

Timeline
59mo left

Started May 2014

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress71%
May 2014Apr 2031

Study Start

First participant enrolled

May 21, 2014

Completed
2.8 years until next milestone

First Submitted

Initial submission to the registry

March 17, 2017

Completed
7 days until next milestone

First Posted

Study publicly available on registry

March 24, 2017

Completed
13 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2030

Expected
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2031

Last Updated

December 22, 2025

Status Verified

December 1, 2025

Enrollment Period

15.9 years

First QC Date

March 17, 2017

Last Update Submit

December 15, 2025

Conditions

Alzheimer DiseaseMild Cognitive Impairment

Keywords

Memory

Outcome Measures

Primary Outcomes (1)

  • Amyloid deposition

    Studying the initial amyloid deposition in participants as well as their rate of amyloid accumulation over time will help establish whether there is an early therapeutic window for intervention in high risk patients.

    2 years

Eligibility Criteria

Age55 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Adults enrolled with the Alzheimer's Disease Research Center at Wake Forest School of Medicine will be invited to participate,

You may qualify if:

  • Enrolled in a study with the Alzheimer's Disease Research Center.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Wake Forest Baptist Medical Center

Winston-Salem, North Carolina, 27157, United States

Location

MeSH Terms

Conditions

Alzheimer DiseaseCognitive Dysfunction

Condition Hierarchy (Ancestors)

DementiaBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesTauopathiesNeurodegenerative DiseasesNeurocognitive DisordersMental DisordersCognition Disorders

Study Officials

  • Suzanne Craft, PhD

    Wake Forest University Health Sciences

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 17, 2017

First Posted

March 24, 2017

Study Start

May 21, 2014

Primary Completion (Estimated)

April 1, 2030

Study Completion (Estimated)

April 1, 2031

Last Updated

December 22, 2025

Record last verified: 2025-12

Data Sharing

IPD Sharing
Will not share

Locations

US(1)