Thermogenic Effect of Ginger

NCT03089593 | Completed DMC

• 1 other identifier: UFMG 30409114.8.0000.5149
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

The main objective of the study is to evaluate the thermogenic effect of ginger.

Conditions

Healthy Volunteers

Keywords

Thermic Effect of Food; Energy Expenditure; Ginger

Outcome Measures

Primary Outcomes (1)

• Change in postprandial energy expenditure

  Energy expenditure will be assessed by indirect calorimetry

  Baseline and thereafter at 30, 60, 120, 180 and 240 minutes postprandial

Secondary Outcomes (7)

• Change in oxygen consumption

  Baseline and thereafter at 30, 60, 120, 180 and 240 minutes postprandial

• Change in blood pressure

  Baseline and thereafter at 30, 60, 120, 180 and 240 minutes postprandial

• Change in axillary temperature

  Baseline and thereafter at 30, 60, 120, 180 and 240 minutes postprandial

• Change in metabolic profile

  Baseline and thereafter at 30, 60, 120 and 240 minutes postprandial

• Change in heart rate

  Baseline and thereafter at 30, 60, 120, 180 and 240 minutes postprandial

Study Arms (2)

Extract of ginger

EXPERIMENTAL

Healthy and eutrophic women will receive two capsules of 200 mg of ginger extract (5% gingerols) to be taken along with a standardized breakfast.

Other: Extract of ginger

Cellulose

PLACEBO COMPARATOR

Healthy and eutrophic women will receive two capsules of 200 mg of placebo (cellulose) to be taken along with a standardized breakfast.

Other: Placebo (Cellulose)

Interventions

Extract of ginger OTHER

The volunteers will receive two capsules containing 200mg of extract of ginger with 5% of gingerols (20 mg). Breakfast will be offered (bread, butter, turkey ham and industrialized fruit juice) and the participants will have 15 minutes to eat it.

Extract of ginger

Placebo (Cellulose) OTHER

The volunteers will receive two capsules containing cellulose (placebo). Breakfast will be offered (bread, butter, turkey ham and industrialized fruit juice) and the participants will have 15 minutes to eat it.

Cellulose

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Females;
• Aged between 18 and 60 years old;
• Body mass index between 18.5 and 24.9 kg/m²;
• Agree to sign the informed consent.

You may not qualify if:

• Any chronic health conditions (e.g. diabetes, hypertension, chronic renal failure, heart and liver disease);
• Previous operation for weight loss;
• Medications known to affect total energy expenditure;
• Pregnancy and breast-feeding;
• Smoking;
• Alcohol use (\>2 doses/day).

Sponsors & Collaborators

• Federal University of Minas Gerais: lead

Study Sites (1)

Hospital das Clínicas

Belo Horizonte, Minas Gerais, 30130-100, Brazil

Location

Related Publications (1)

• Fagundes GBP, Rodrigues AMDS, Martins LB, Monteze NM, Correia MITD, Teixeira AL, Ferreira AVM. Acute effects of dry extract of ginger on energy expenditure in eutrophic women: A randomized clinical trial. Clin Nutr ESPEN. 2021 Feb;41:168-174. doi: 10.1016/j.clnesp.2020.10.001. Epub 2020 Nov 9.

  PMID: 33487261 DERIVED

MeSH Terms

Interventions

Cellulose

Intervention Hierarchy (Ancestors)

Glucans; Biopolymers; Polymers; Macromolecular Substances; Polysaccharides; Carbohydrates; Biomedical and Dental Materials; Manufactured Materials; Technology, Industry, and Agriculture

Study Officials

• Gabriela BP Fagundes

  Federal University of Minas Gerais

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: OTHER
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator, PhD

Study Record Dates

• First Submitted: March 8, 2017
• First Posted: March 24, 2017
• Study Start: March 27, 2017
• Primary Completion: June 14, 2017
• Study Completion: June 14, 2017
• Last Updated: June 21, 2017

Record last verified: 2017-06

Locations

BR (1)