NCT03074721

Brief Summary

The PCI Suite is developed by Philips Medical Systems, a Philips Healthcare company. The proposed PCI Suite is a new software package which can be used during coronary interventions. The software package includes two sub-packages, known as StentBoost and Cardiac Roadmapping. The patient will undergo standard of care medical treatment for his or her cardiac condition. During the procedure, the physician may make angiograms for diagnosis and as reference for device navigation as part of the standard care. These angiograms will be automatically processed in PCI Suite and displayed on fluoroscopy for navigation support. In case a balloon catheter is inserted into the coronary arteries, the physician may take cine images as part of the standard care. These images can be automatically enhanced in PCI Suite. The primary objective of this prospective, mono-center, randomized clinical trial is to evaluate the amount of contrast medium used during percutaneous coronary intervention.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
130

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Apr 2017

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 13, 2017

Completed
24 days until next milestone

First Posted

Study publicly available on registry

March 9, 2017

Completed
2 months until next milestone

Study Start

First participant enrolled

April 24, 2017

Completed
4.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2021

Completed
Last Updated

February 7, 2020

Status Verified

February 1, 2020

Enrollment Period

4.6 years

First QC Date

February 13, 2017

Last Update Submit

February 6, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Amount of contrast medium

    Determination during PCI

    Baseline

Secondary Outcomes (4)

  • Major adverse cardiac and cerebrovascular events

    Baseline, after 6 months, after 12 months

  • Procedural success

    Baseline

  • Procedure duration

    Baseline

  • area dosage product

    Baseline

Study Arms (2)

PCI with PCI Suite Software

OTHER
Device: PCI Suite Software

conventional PCI

OTHER
Other: conventional PCI

Interventions

PCI with PCI Suite Software

PCI with PCI Suite Software

conventional PCI without PCI Software

conventional PCI

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • hemodynamically relevant type A or B lesion

You may not qualify if:

  • hemodynamically relevant type C lesion
  • NSTEMI/STEMI
  • declined to participate

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Division of Cardiology, Pulmonary Disease and Vascular Medicine

Düsseldorf, 40225, Germany

RECRUITING

Related Publications (1)

  • Quast C, Phinicarides R, Afzal S, Veulemans V, Klein K, Berisha N, Leuders P, Erkens R, Jung C, Bonner F, Kelm M, Polzin A, Zeus T. Roadmap fusion imaging in percutaneous coronary intervention reduces contrast medium exposure irrespective of investigator's experience level. J Invasive Cardiol. 2024 Jan;36(1). doi: 10.25270/jic/23.00203.

MeSH Terms

Conditions

Coronary Disease

Condition Hierarchy (Ancestors)

Myocardial IschemiaHeart DiseasesCardiovascular DiseasesVascular Diseases

Study Officials

  • Tobias Zeus, MD

    Division of Cardiology, Pulmonology and Vascular Medicine, University Hospital Duesseldorf

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 13, 2017

First Posted

March 9, 2017

Study Start

April 24, 2017

Primary Completion

December 1, 2021

Study Completion

December 1, 2021

Last Updated

February 7, 2020

Record last verified: 2020-02

Data Sharing

IPD Sharing
Will not share

Locations