NCT03071796

Brief Summary

In this study the investigator will evaluate whether a liquid multivitamin supplement influences blood and vital parameters. Furthermore the investigator will establish the effects on life quality, mood and perception of stress and will characterize changes on immune system.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Mar 2017

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 21, 2017

Completed
14 days until next milestone

First Posted

Study publicly available on registry

March 7, 2017

Completed
Same day until next milestone

Study Start

First participant enrolled

March 7, 2017

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 15, 2017

Completed
5 days until next milestone

Study Completion

Last participant's last visit for all outcomes

June 20, 2017

Completed
Last Updated

June 23, 2017

Status Verified

June 1, 2017

Enrollment Period

3 months

First QC Date

February 21, 2017

Last Update Submit

June 22, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Plasma concentration of Vitamin B12

    vitamin B12 \[pmol/l\]

    change measures (baseline to 12 weeks)

Secondary Outcomes (7)

  • Analysis of blood pressure

    change measures (baseline to 12 weeks)

  • Analysis of heart rate variability

    change measures (baseline to 12 weeks)

  • Analysis of speed of pulse wave,

    change measures (baseline to 12 weeks)

  • Plasma concentration of 25-hydroxyvitamin D

    change measures (baseline to 12 weeks)

  • Plasma concentration of folic acid

    change measures (baseline to 12 weeks)

  • +2 more secondary outcomes

Other Outcomes (4)

  • Susceptibility to infections

    up to 12 weeks

  • assessment of life quality

    change measures (baseline to 12 weeks)

  • assessment of mood

    change measures (baseline to 12 weeks)

  • +1 more other outcomes

Study Arms (2)

multivitamin supplement

EXPERIMENTAL

liquid multivitamin supplement for 12 weeks

Dietary Supplement: multivitamin supplement

placebo

PLACEBO COMPARATOR

liquids with similar appearance and taste like multivitamin supplement for 12 weeks

Dietary Supplement: Placebo

Interventions

multivitamin supplementDIETARY_SUPPLEMENT

supplement includes 97 natural extracts

multivitamin supplement
PlaceboDIETARY_SUPPLEMENT

liquids with similar appearance and taste like multivitamin supplement for 12 weeks

placebo

Eligibility Criteria

Age30 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • healthy women and men
  • age between 30-60 years
  • employed

You may not qualify if:

  • acute and chronic diseases (including diabetes, inflammatory bowel diseases, dementia, multiple sclerosis)
  • frequent use of alcohol, drugs or cigarettes (\>5 cigarettes / day)
  • use of additional supplements
  • use of medications (e.g. antihypertensive medications, lipid reducers, thyroid medication)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Halle-Wittenberg

Halle, 06120, Germany

Location

MeSH Terms

Conditions

Health Behavior

Condition Hierarchy (Ancestors)

Behavior

Study Officials

  • Kuno Hottenrott, Prof. Dr.

    University of Halle-Wittenberg, Department of Sports

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Masking Details
double-blind
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Prof. Dr.; University of Halle-Wittenberg, Department of Sports

Study Record Dates

First Submitted

February 21, 2017

First Posted

March 7, 2017

Study Start

March 7, 2017

Primary Completion

June 15, 2017

Study Completion

June 20, 2017

Last Updated

June 23, 2017

Record last verified: 2017-06

Data Sharing

IPD Sharing
Will not share

Locations