Study Stopped
The study was stopped for futility based on efficacy results at the interim analysis; no unexpected safety findings were observed.
Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)
PROMINENT
1 other identifier
interventional
10,544
25 countries
888
Brief Summary
The primary objective of the study is to determine whether pemafibrate administered twice daily will delay the time to first occurrence of any component of the clinical composite endpoint of:
- nonfatal Myocardial Infarction (MI)
- nonfatal ischemic stroke
- coronary revascularization; or
- Cardio Vascular (CV) death.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for phase_3
Started Mar 2017
Longer than P75 for phase_3
888 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
February 23, 2017
CompletedFirst Posted
Study publicly available on registry
March 7, 2017
CompletedStudy Start
First participant enrolled
March 23, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 27, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
July 27, 2022
CompletedResults Posted
Study results publicly available
September 25, 2025
CompletedSeptember 25, 2025
September 1, 2025
5.3 years
February 23, 2017
July 10, 2025
September 5, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
Number of Participants With First Occurrence of 4-component Composite Primary Endpoint (Nonfatal MI, Nonfatal Ischemic Stroke, Coronary Revascularization, or CV Death)
Number of participants experiencing their first occurrence of any component of the 4-component composite primary endpoint, which includes nonfatal myocardial infarction (MI), nonfatal ischemic stroke, coronary revascularization, or cardiovascular (CV) death. Each participant is counted only once, regardless of any subsequent events.
From Baseline to a Median of 3.3 Years
Secondary Outcomes (20)
Number of Participants With First Occurrence of the 4-component Composite Secondary Endpoint (Nonfatal MI, Nonfatal Ischemic Stroke, Hospitalization for Unstable Angina Requiring Unplanned Coronary Revascularization, or CV Death)
From Baseline to a Median of 3.3 Years
Number of Participants With First Occurrence of the 3-component Composite Endpoint (Nonfatal Myocardial Infarction, Nonfatal Ischemic Stroke, or Cardiovascular Death)
From Baseline to a Median of 3.3 Years
Number of Participants With First Occurrence of Any Component of the Primary Endpoint or Hospitalization for Heart Failure
From Baseline to a Median of 3.3 Years
Number of Participants With Occurrence of Any Component of the Primary Endpoint or All-Cause Mortality
From Baseline to a Median of 3.3 Years
Total Number of Events of the 4-component Composite Primary Endpoint
From Baseline to a Median of 3.3 Years
- +15 more secondary outcomes
Study Arms (2)
Treatment Group
EXPERIMENTALK-877 (pemafibrate) tablet twice daily.
Control Group
PLACEBO COMPARATORMatching K-877 placebo tablet twice daily.
Interventions
Eligibility Criteria
You may qualify if:
- Fasting TG ≥ 200 mg/dL (2.26 mmol/L) and \< 500 mg/dL (5.65 mmol/L) at Visit 1 (Screening/Enrollment Visit) or Visit 1.1 (Retest)
- HDL-C ≤ 40 mg/dL (1.03 mmol/L) at Visit 1 (Screening/Enrollment Visit) or Visit 1.1 (Retest)
- Type 2 diabetes of longer than 12 weeks duration documented in medical records, for example: local laboratory evidence through medical record review of elevated HbA1c (≥ 6.5% \[48 mmol/mol\]), elevated plasma glucose (fasting ≥ 126 mg/dL \[7.0 mmol/L\], 2-hour ≥ 200 mg/dL \[11.1 mmol/L\] during oral glucose tolerance testing, or random value ≥ 200 mg/dL with classic symptoms, or currently taking medication for treatment of diabetes; AND either
- Age ≥ 50 years if male or ≥ 55 years if female (primary prevention cohort); OR
- Age ≥ 18 years and established systemic atherosclerosis (secondary prevention cohort), defined as any 1 of the following:
- i. Prior MI or ischemic (non-hemorrhagic) stroke
- ii. Coronary angiographic lesion of ≥ 60% stenosis in a major epicardial vessel or ≥ 50% left main stenosis
- iii. Asymptomatic carotid disease with ≥ 70% carotid artery stenosis
- iv. Symptomatic carotid disease with ≥ 50% carotid artery stenosis
- v. Symptomatic lower extremity PAD (ie, intermittent claudication, rest pain, lower extremity ischemic ulceration, or major amputation with either ankle-brachial index ≤ 0.9 or other diagnostic testing \[eg, toe-brachial index, angiogram, or other imaging study\])
- vi. Prior arterial revascularization procedure (including coronary, carotid, or peripheral angioplasty/stenting, bypass, or atherectomy/endarterectomy)
You may not qualify if:
- Current or planned use of fibrates or agents with PPAR-α agonist activity (eg, saroglitazar) within 6 weeks (42 days) of Visit 1 (Screening/Enrollment Visit). Note: PPAR-γ agonists (eg, glizatones such as pioglitazone and rosiglitazone) are allowed
- Known sensitivity to PPAR-α agonists or tablet excipients
- Initiation of, or change in, current TG-lowering therapy within 12 weeks of Visit 1 (if applicable). Note: TG-lowering therapy is defined as niacin \> 100 mg/day or dietary supplements or prescription omega-3 fatty acids \> 1 g/day
- Type 1 diabetes mellitus
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Kowa Research Institute, Inc.lead
- Brigham and Women's Hospitalcollaborator
Study Sites (888)
Synexus Clinical Research US, Inc.
Birmingham, Alabama, 35211, United States
University of Alabama at Birmingham
Birmingham, Alabama, 35233, United States
VA Medical Center - Birmingham
Birmingham, Alabama, 35233, United States
Alabama Clinical Therapeutics, LLC
Birmingham, Alabama, 35235, United States
Fundamental Research, LLC
Gulf Shores, Alabama, 36542, United States
Mobile Heart Specialists, PC
Mobile, Alabama, 36608, United States
Terence T. Hart, MD
Tuscumbia, Alabama, 35674, United States
Synexus Clinical Research US, Inc.
Chandler, Arizona, 85224-6279, United States
Synexus Clinical Research US, Inc.
Mesa, Arizona, 85206, United States
Arizona Arthritis & Rheumatology Research, PLLC
Peoria, Arizona, 85381, United States
Phoenix Veterans Adminstration Health Care System
Phoenix, Arizona, 85012, United States
Synexus Clinical Research US, Inc.
Phoenix, Arizona, 85050, United States
Clinical Research Institute of Arizona, LLC
Surprise, Arizona, 85374, United States
Synexus Clinical Research US, Inc.
Tucson, Arizona, 85712, United States
Eclipse Clinical Research
Tucson, Arizona, 85745, United States
Central Arkansas Veterans Healthcare System
Little Rock, Arkansas, 72205, United States
Clinical Research Alliance, Inc
Alhambra, California, 91801, United States
Aurora Care Clinic
Costa Mesa, California, 92627, United States
AMCR Institute, Inc.
Escondido, California, 92025, United States
National Institute of Clinical Research
Huntington Beach, California, 92648-1717, United States
VA Loma Linda Healthcare System
Loma Linda, California, 92354, United States
VA Long Beach Healthcare System
Long Beach, California, 90822, United States
Eastside Clinical Research Associates
Los Angeles, California, 90022, United States
VA Greater Los Angeles Healthcare System
Los Angeles, California, 90073, United States
Richard S. Cherlin, MD
Los Gatos, California, 95032, United States
Northridge Clinical Research Inc.
Northridge, California, 91324, United States
Palo Alto Division
Palo Alto, California, 94304, United States
Huntington Hospital - Research Department
Pasadena, California, 91105, United States
Rancho Cucamonga Clinical Research
Rancho Cucamonga, California, 91730, United States
MD Strategies Research Centers
San Diego, California, 92119, United States
Alex Harrison, MD Inc.
Santa Maria, California, 93454, United States
Santa Rosa Cardiology Medical Group, Inc.
Santa Rosa, California, 95404, United States
Blue Coast Cardiology
Vista, California, 92083, United States
Lynn Institute of Denver
Aurora, Colorado, 80012, United States
New West Physicians, PC
Golden, Colorado, 80401, United States
Southwest Family Medicine
Littleton, Colorado, 80127, United States
Chase Medical Research, LLC
Waterbury, Connecticut, 06708, United States
VA Connecticut Healthcare Sys
West Haven, Connecticut, 06516-2770, United States
Cardiology Physicians, PA
Newark, Delaware, 19713, United States
Bay Pines VA Healthcare System
Bay Pines, Florida, 33744, United States
Meridien Research
Bradenton, Florida, 34201, United States
Clinical Research Of Brandon, LLC
Brandon, Florida, 33511, United States
Clearwater Cardiovascular Consultants
Clearwater, Florida, 33756, United States
Daytona Heart Group
Daytona Beach, Florida, 32114, United States
Cohen Medical Research Associates, LLC
Delray Beach, Florida, 33446, United States
Malcom Randall VA Medical Center
Gainesville, Florida, 32608, United States
Pines Clinical Research, Inc.
Hollywood, Florida, 33024, United States
Homestead Cardiac & Vein Center
Homestead, Florida, 33030, United States
Westside Center for Clinical Research
Jacksonville, Florida, 32205, United States
Jacksonville Center for Clinical Research
Jacksonville, Florida, 32216, United States
Health Awareness, Inc.
Jupiter, Florida, 33458, United States
Meridien Research
Lakeland, Florida, 33805, United States
Clearwater Cardiovascular & Interventional Consultants
Largo, Florida, 33777, United States
University of Miami
Miami, Florida, 33136, United States
Advanced Medical Research Institute
Miami, Florida, 33174, United States
Ocala Research Institute, Inc.
Ocala, Florida, 34471, United States
Morgan Medical Management & Consultants Inc.
Ocala, Florida, 34474, United States
Endocrine Associates of Florida
Ocoee, Florida, 34761, United States
Research Physicians Network Alliance
Orlando, Florida, 32803, United States
Andres Patron, D.O., P.A
Pembroke Pines, Florida, 33026, United States
DBC Research, Corp
Pembroke Pines, Florida, 33029, United States
Langhorne Cardiology Consultants, Inc.
Pensacola, Florida, 32501, United States
Clearwater Cardiovascular Consultants
Safety Harbor, Florida, 34695, United States
Professional Health Care of Pinellas
St. Petersburg, Florida, 33713, United States
James A. Haley VA Medical Center
Tampa, Florida, 33612, United States
Clinical Research of Central Florida
Winter Haven, Florida, 33880, United States
Emory University
Atlanta, Georgia, 30322, United States
Atlanta Heart Specialists, LLC
Cumming, Georgia, 30041, United States
VA Medical Center - Atlanta
Decatur, Georgia, 30033, United States
Alta Pharmaceutical Research Center, Inc.
Dunwoody, Georgia, 30338, United States
Atlanta Heart Specialists, LLC
Tucker, Georgia, 30084, United States
Christie Clinic, LLC
Champaign, Illinois, 61822, United States
Apex Medical Research, AMR, Inc.
Chicago, Illinois, 60607, United States
Clinical Investigation Specialists, Inc.
Gurnee, Illinois, 60031, United States
Edward Hines Jr. VA Hospital
Hines, Illinois, 60141, United States
Advocate Health and Hospitals Corp
Normal, Illinois, 61761, United States
Captain James A. Lovell Federal Health Care Center
North Chicago, Illinois, 60064, United States
Specialty Physicians of Illinois
Olympia Fields, Illinois, 60461, United States
Community Hospital of Anderson and Madison County, Inc.
Anderson, Indiana, 46011, United States
Synexus Clinical Research US, Inc.
Evansville, Indiana, 47714, United States
Deaconess Clinic
Evansville, Indiana, 47725, United States
VA Medical Center - Indianapolis
Indianapolis, Indiana, 46202, United States
Cardiovascular Research of Northwest Indiana, LLC
Munster, Indiana, 46321, United States
Buynak Clinical Research
Valparaiso, Indiana, 46383, United States
West Broadway Clinic
Council Bluffs, Iowa, 51501, United States
Iowa Diabetes and Endocrinology Research Center, PLC
Des Moines, Iowa, 50314, United States
The Iowa Clinic, PC
West Des Moines, Iowa, 50266, United States
University of Kansas Medical Center Research Institute, Inc.
Kansas City, Kansas, 66160, United States
VA Eastern Kansas Health Care
Leavenworth, Kansas, 66048, United States
The Research Group of Lexington, LLC
Lexington, Kentucky, 40503, United States
Robley Rex VA Medical Center
Louisville, Kentucky, 40206, United States
Cambridge Medical Trials
Alexandria, Louisiana, 71301, United States
Cardiovascular Associates Research, LLC
Covington, Louisiana, 70433, United States
Centex Studies Inc.
Lake Charles, Louisiana, 70601, United States
Overton Brooks VA Medical Center
Shreveport, Louisiana, 71101, United States
Southern Maine Health Care
Biddeford, Maine, 04005, United States
Baltimore VA medical centre
Baltimore, Maryland, 21201, United States
University of Maryland School of Medicine
Baltimore, Maryland, 21201, United States
Maryland Cardiovascular Specialists
Baltimore, Maryland, 21229, United States
Medstar Health Research Institute
Hyattsville, Maryland, 20782, United States
Delmarva Heart Research Foundation, Inc.
Salisbury, Maryland, 21804, United States
Joslin Diabetes Center
Boston, Massachusetts, 02215, United States
Pentucket Medical Associates
Haverhill, Massachusetts, 01830, United States
South Shore Internal Medicine Associates
Milton, Massachusetts, 02186, United States
University of Michigan
Ann Arbor, Michigan, 48105, United States
Veterans Affairs Ann Arbor Healthcare System
Ann Arbor, Michigan, 48105, United States
Northern Pines Health Center
Buckley, Michigan, 49620, United States
Cadillac Clinical Research, LLC
Cadillac, Michigan, 49601, United States
AA MRC LLC Ahmed Arif Medical Research Center
Flint, Michigan, 48504, United States
Sparrow Clinical Research Institute
Lansing, Michigan, 48912, United States
Covenant Medical Center, Inc.
Saginaw, Michigan, 48602, United States
Minneapolis Heart Institute Foundation
Minneapolis, Minnesota, 55407, United States
Synexus Clinical Research US, Inc.
Richfield, Minnesota, 55432, United States
CentraCare Heart & Vascular
Saint Cloud, Minnesota, 56303-1900, United States
HealthEast Medical Research Institute
Saint Paul, Minnesota, 55102, United States
GV Montgomery VA Medical Center
Jackson, Mississippi, 39216, United States
Kansas City VA Medical Center
Kansas City, Missouri, 64128, United States
Synexus Clinical Research US, Inc.
St Louis, Missouri, 63141, United States
Kalispell Regional Medical Center dba Glacier View Research Institute
Kalispell, Montana, 59901, United States
VA Nebraska-Western Iowa Health Care System
Omaha, Nebraska, 68105, United States
University of Nebraska Medical Center
Omaha, Nebraska, 68198-4120, United States
Synexus Clinical Research US, Inc.
Papillion, Nebraska, 68046, United States
Synexus Clinical Research US, Inc.
Henderson, Nevada, 89052, United States
Red Rock Clinical Research LLC
Las Vegas, Nevada, 89146, United States
VA Sierra Nevada Health Care System
Reno, Nevada, 89502, United States
Southern New Hampshire Diabetes and Endocrinology
Nashua, New Hampshire, 03063, United States
Monmouth Cardiology Associates
Eatontown, New Jersey, 07724, United States
NJ Heart
Linden, New Jersey, 07036, United States
The Valley Hospital
Ridgewood, New Jersey, 07450, United States
Raymond G. Murphy VA Medical Center
Albuquerque, New Mexico, 87108, United States
Endocrine Group, L.L.P.
Albany, New York, 12206, United States
Stratton Veterans Affairs Medical Center - Albany
Albany, New York, 12208, United States
Buffalo VA Medical Center
Buffalo, New York, 14215, United States
Winthrop Cardiology Associates
Mineola, New York, 11501, United States
Icahn School of Medicine at Mount Sinai
New York, New York, 10029, United States
SUNY Upstate Medical University
Syracuse, New York, 13210, United States
VA Medical Center - Syracuse
Syracuse, New York, 13210, United States
Randolph Medical Associates
Asheboro, North Carolina, 27203, United States
OnSite Clinical Solutions, LLC
Asheville, North Carolina, 28801, United States
Kernodle Clinic, Inc., Dept. of the Private Diagnostic Clinic, PLLC
Burlington, North Carolina, 27215, United States
Cary Research Group, LLC
Cary, North Carolina, 27518, United States
PMG Research of Cary, LLC
Cary, North Carolina, 27518, United States
Novant Health - Heart and Vascular Institute
Charlotte, North Carolina, 28204, United States
The Presbyterian Hospital
Charlotte, North Carolina, 28204, United States
Focus Clinical Research Solutions
Charlotte, North Carolina, 28277, United States
Medication Management, LLC
Greensboro, North Carolina, 27408, United States
Triad Clinical Trials, LLC
Greensboro, North Carolina, 27410, United States
Clinical Trials of America-NC, LLC
Hickory, North Carolina, 28601, United States
PMG Research of Hickory, LLC
Hickory, North Carolina, 28601, United States
Research Institute of the Carolinas, PLC
Mooresville, North Carolina, 28117, United States
Diabetes and Endocrinology Consultants
Morehead City, North Carolina, 28557, United States
Pinehurst Medical Clinic Inc
Pinehurst, North Carolina, 28374, United States
PMG Research of Raleigh, LLC
Raleigh, North Carolina, 27609, United States
PMG Research of Rocky Mount, LLC
Rocky Mount, North Carolina, 27804, United States
PMG Research of Salisbury, LLC
Salisbury, North Carolina, 28144, United States
Carolina Research Center, Inc.
Shelby, North Carolina, 28150-3803, United States
Synexus Clinical Research US, Inc.
Akron, Ohio, 44311, United States
OhioHealth Heart & Vascular Physicians (Heartcare, Inc.) - Athens
Athens, Ohio, 45701, United States
Aultman Hospital
Canton, Ohio, 44710, United States
Hometown Urgent Care & Occupational Health
Cincinnati, Ohio, 45215, United States
Cincinnati Veterans Affairs Medical Center
Cincinnati, Ohio, 45267, United States
Louis Stokes Cleveland Dept of VA Medical Center
Cleveland, Ohio, 44106, United States
Prestige Clinical Research Center
Franklin, Ohio, 45005, United States
Craig S Thompson MD LLC
Marion, Ohio, 43302, United States
Intend Research
Norman, Oklahoma, 73069, United States
Lynn Institute of Norman
Norman, Oklahoma, 73069, United States
Oklahoma City Clinic - Central
Oklahoma City, Oklahoma, 73104, United States
South Oklahoma Heart Research Group
Oklahoma City, Oklahoma, 73135, United States
Heart Clinic of Southern Oregon
Medford, Oregon, 97504, United States
Chambersburg Hospital
Chambersburg, Pennsylvania, 17201, United States
AMH Feasterville Family Health Care Center
Feasterville, Pennsylvania, 19053, United States
Family Medical Associates
Levittown, Pennsylvania, 19056, United States
VA Pittsburgh Healthcare System
Pittsburgh, Pennsylvania, 15240, United States
Preferred Primary Care Physicians
Pittsburgh, Pennsylvania, 15317, United States
Fay West Family Practice
Scottdale, Pennsylvania, 15683, United States
Montgomery Medical Inc.
Smithfield, Pennsylvania, 15478, United States
Partners in Clinical Research
Cumberland, Rhode Island, 02864, United States
Ocean State Clinical Research Partners
Lincoln, Rhode Island, 02865, United States
Providence Veteran Administration Medical Center
Providence, Rhode Island, 02908, United States
Synexus Clinical Research US, Inc.
Anderson, South Carolina, 29621-2062, United States
Ralph H. Johnson VA Medical Center
Charleston, South Carolina, 29401, United States
Mountain View Clinical Research, Inc.
Greer, South Carolina, 29651, United States
Main Street Physician's Care - Waterway
Little River, South Carolina, 29566, United States
Family Medicine of Sayebrook
Myrtle Beach, South Carolina, 29588, United States
Piedmont Research Partners
Old Point Station, South Carolina, 29707, United States
Palmetto Research Center, LLC
Spartanburg, South Carolina, 29302, United States
Palmetto Clinical Research
Summerville, South Carolina, 29485, United States
PMG Research of Bristol, LLC
Bristol, Tennessee, 37620, United States
Chattanooga Medical Research, LLC
Chattanooga, Tennessee, 37404, United States
Chattanooga Research and Medicine (CHARM)
Chattanooga, Tennessee, 37404, United States
University Diabetes & Endocrine Consultants
Chattanooga, Tennessee, 37411, United States
WR-ClinSearch, LLC
Chattanooga, Tennessee, 37421, United States
Holston Medical Group, P.C.
Kingsport, Tennessee, 37660, United States
Metro Knoxville HMA, LLC
Knoxville, Tennessee, 37934, United States
VA Medical Center - Memphis
Memphis, Tennessee, 38104, United States
Tennessee Valley Healthcare System
Nashville, Tennessee, 37232, United States
Central Texas Clinical Research, LLC
Austin, Texas, 78705, United States
Protenium Clinical Research
Dallas, Texas, 75208, United States
VA Medical Center - Dallas
Dallas, Texas, 75216, United States
North Texas Endocrine Center
Dallas, Texas, 75231, United States
Research Institute of Dallas, P.A.
Dallas, Texas, 75231, United States
Synexus Clinical Research US, Inc.
Dallas, Texas, 75234, United States
Doctors Hospital at Renaissance
Edinburg, Texas, 78539, United States
Texas Health Research & Education Institute
Fort Worth, Texas, 76104, United States
Texas Health Physicians Group
Fort Worth, Texas, 76107, United States
University of North Texas Health Science Center
Fort Worth, Texas, 76107, United States
Diabetes and Thyroid Center of Fort Worth
Fort Worth, Texas, 76132, United States
Rockwood Medical Clinic
Fort Worth, Texas, 76164, United States
East Texas Cardiology PA
Houston, Texas, 77002, United States
Endocrine Associates, LLC
Houston, Texas, 77004, United States
Heights Doctors Clinic
Houston, Texas, 77008, United States
Associates in Medicine
Houston, Texas, 77027, United States
Michael E. DeBakey VA Medical Center
Houston, Texas, 77030, United States
Southwest Clinical Trials
Houston, Texas, 77081, United States
Protenium Clinical Research
Hurst, Texas, 76054, United States
Houston Methodist Research Institute - CCAT Pearland
Pearland, Texas, 77584, United States
Clinical Investigations of Texas
Plano, Texas, 75075, United States
Consano Clinical Research, LLC
San Antonio, Texas, 78205, United States
Sant Antonio Premiere Internal Medicine
San Antonio, Texas, 78220, United States
Briggs Clinical Research, LLC.
San Antonio, Texas, 78224, United States
Schnitzler Cardiovascular Consultants (SCC), PLLC
San Antonio, Texas, 78229-3271, United States
Bandera Family Healthcare Research LLC
San Antonio, Texas, 78249, United States
Northeast Clinical Research of San Antonio
Schertz, Texas, 78154, United States
Spring Family Practice Associates
Spring, Texas, 77379, United States
Northwest Houston Heart Center
Tomball, Texas, 77375, United States
Victoria Heart & Vascular Center
Victoria, Texas, 77901, United States
Hillcrest Family Health Clinics
Waco, Texas, 76710, United States
Utah Cardiology, P.C. (Davis)
Farmington, Utah, 84025, United States
VA Medical Center
White River Junction, Vermont, 05055, United States
Burke Internal Medicine & Research
Burke, Virginia, 22015, United States
Virginia Endocrinology Research
Chesapeake, Virginia, 23321, United States
Carient Heart and Vascular
Manassas, Virginia, 20109, United States
Clinical Research Partners, LLC
Richmond, Virginia, 23220, United States
McGuire DVA Medical Center
Richmond, Virginia, 23249, United States
Roanoke Heart Institute
Roanoke, Virginia, 24014, United States
Suffolk Multispecialty Research
Suffolk, Virginia, 23435, United States
Corporation Lane Internal Medicine
Virginia Beach, Virginia, 23462, United States
Cardiology Associates of Bellin Health
Green Bay, Wisconsin, 54301, United States
Clinical Investigation Specialists Inc
Kenosha, Wisconsin, 53144, United States
Mayo Clinic Health System
La Crosse, Wisconsin, 54601, United States
Meriter Medical Group, Inc.
Madison, Wisconsin, 53713, United States
Zablocki VA Medical Center
Milwaukee, Wisconsin, 53295, United States
Hospital Interzonal General de Agudos Dr Jose Penna
Bahía Blanca, Buenos Aires, 8000, Argentina
Hospital Italiano Regional del Sur
Bahía Blanca, Buenos Aires, B8001HXM, Argentina
Hospital Italiano
Ciudad Autonoma Buenos Aires, Buenos Aires, C1181ACH, Argentina
CICLO
La Plata, Buenos Aires, B1902AGY, Argentina
Centro de Investigaciones Medicas Mar del Plata
Mar del Plata, Buenos Aires, B7600FYK, Argentina
Instituto de Investigaciones Clinicas
Mar del Plata, Buenos Aires, B7600FZ, Argentina
Instituto de Investigaciones Clinicas San Nicolas
San Nicolás de los Arroyos, Buenos Aires, B2900DMH, Argentina
Instituto Clinico Metabolico
San Nicolás de los Arroyos, Buenos Aires, B2900DPA, Argentina
Clinica Olivos
Vicente López, Buenos Aires, 1602, Argentina
Centro Medico Viamonte SRL
Buenos Aires, Ciudad Autonoma Buenos Aires, C1120AAC, Argentina
Hospital Sirio Libanes
Caba, Ciudad Autonoma Buenos Aires, C1419GEP, Argentina
Sanatorio Güemes
Ciudad Autonoma de Bs. As., Ciudad Autonoma Buenos Aires, C1180AAX, Argentina
CEMEDIC - Centro de Especialidades Medicas
Villa Luro, Ciudad Autonoma Buenos Aires, C1440CFD, Argentina
Centro Medico Luquez
San Vicente, Córdoba Province, X5006CBI, Argentina
Axismed S.R.L.- Clínica Mayo
San Miguel de Tucumán, Tucumán Province, 4000, Argentina
Consultorio Dr. Litvak Bruno
Ciudad Autonoma Buenos Aires, 1406, Argentina
Fundacion Favaloro
Ciudad Autonoma Buenos Aires, C1093AAS, Argentina
CIPREC
Ciudad Autonoma Buenos Aires, C1119ACN, Argentina
Investigaciones Medicas IMOBA S.R.L
Ciudad Autonoma Buenos Aires, C1179AAB, Argentina
Centro Medico Dra Laura Maffei Investigacion Clinica Aplicada
Ciudad Autonoma Buenos Aires, C1425AGC, Argentina
CEDIC Centro de Investigaciones Clinicas
Ciudad Autonoma Buenos Aires, C1425DES, Argentina
Instituto Cardiovascular Buenos Aires
Ciudad Autonoma Buenos Aires, C1428ART, Argentina
CCBR - Buenos Aires - AR
Ciudad Autonoma Buenos Aires, C1430CKE, Argentina
Instituto de Cardiologia de Corrientes
Corrientes, 3400, Argentina
Inst. Privado de Inv. Clinicas de Cordoba
Córdoba, X5000AAW, Argentina
Instituto Medico DAMIC
Córdoba, X5003DCE, Argentina
Hospital Privado Centro Medico de Cordoba S.A
Córdoba, X5016KEH, Argentina
Clinica del Prado
Córdoba, X5020AAA, Argentina
Prevencion Cardiovascular Salta
Salta, A4400CRC, Argentina
L2IP - Instituto de Pesquisas Clínicas Ltda.
Brasília, Federal District, 70200-730, Brazil
Hospital do Coração do Brasil
Brasília, Federal District, 70390903, Brazil
CECAP - Centro de Cardiologia Clínica
Brasília, Federal District, 70710-100, Brazil
Hospital Universitário de Brasília
Brasília, Federal District, 70840-091, Brazil
Clínica de Endocrinologia e Metabologia Ltda.
Brasília, Federal District, 71655-175, Brazil
CARDIOINTERV Centro de Pesquisa S/S
Goiânia, Goiás, 74210-050, Brazil
Via Médica
Goiânia, Goiás, 74223-130, Brazil
HC-UFG - Hospital das Clínicas da Universidade Federal de Goiás
Goiânia, Goiás, 74605-020, Brazil
Hospital Felício Rocho
Belo Horizonte, Minas Gerais, 30110-060, Brazil
CARDRESEARCH - Cardiologia Assistencial
Belo Horizonte, Minas Gerais, 30150-240, Brazil
Sociedade Hospitalar Angelina Caron
Campina Grande do Sul, Paraná, 83430-000, Brazil
Cline Research Center (Leite PS Consultoria Medica LTDA)
Curitiba, Paraná, 80030-480, Brazil
Núcleo de Pesquisa Clínica S/S
Curitiba, Paraná, 80730-150, Brazil
Paraná Medical Research Center
Maringá, Paraná, 87015-000, Brazil
HUJBB-UFPA - Hospital Universitário João de Barros Barreto - Universidade Federal do Pará
Belém, Pará, 66073-000, Brazil
CCBR Brasil Centro de Pesquisas e Análises Clínicas Ltda.
Rio de Janeiro, Rio Do Janeiro, 22271-100, Brazil
Eurolatino Natal Pesquisas Médicas Ltda.
Natal, Rio Grande do Norte, 59020-500, Brazil
Hospital Universitário
Canoas, Rio Grande do Sul, 92425-900, Brazil
Hospital São Vicente de Paulo
Passo Fundo, Rio Grande do Sul, 99010-080, Brazil
Santa Casa de Misericórdia de Pelotas
Pelotas, Rio Grande do Sul, 96015-290, Brazil
Santa Casa de Misericórdia de Porto Alegre
Porto Alegre, Rio Grande do Sul, 90035-074, Brazil
Hospital de Clínicas de Porto Alegre
Porto Alegre, Rio Grande do Sul, 90035-903, Brazil
Centro de Pesquisas em Diabetes Ltda.
Porto Alegre, Rio Grande do Sul, 90430-001, Brazil
Centro de Pesquisa Clínica Maimônides - Maimônides Day Hospital
Porto Alegre, Rio Grande do Sul, 90480-000, Brazil
Centro de Pesquisa Médica Santa Maria Ltda.
Santa Maria, Rio Grande do Sul, 97015-530, Brazil
Maestri e Kormann Consultoria Medico Científica LTDA
Blumenau, Santa Catarina, 89010-906, Brazil
Loema - Instituto de Pesquisa Clínica
Campinas, São Paulo, 13010-001, Brazil
IPCC - Instituto de Pesquisa Clínica de Campinas
Campinas, São Paulo, 13060-080, Brazil
CEMEC - Centro Multidisciplinar de Estudos Clínicos
São Bernardo do Campo, São Paulo, 09780-000, Brazil
Fundação Faculdade Regional de Medicina de São José do Rio Preto
São José do Rio Preto, São Paulo, 15090-000, Brazil
ISPEM - Instituto São José dos Campos em Pesquisas Médicas
São José dos Campos, São Paulo, 12243-280, Brazil
CPQuali Pesquisa Clínica Ltda.
São Paulo, São Paulo, 01228-000, Brazil
CPCLIN - Centro de Pesquisas Clínicas Ltda.
São Paulo, São Paulo, 01228-200, Brazil
Clínica Paulista de Doenças Cardiovasculares Ltda.
São Paulo, São Paulo, 01323-000, Brazil
Dr. Consulta
São Paulo, São Paulo, 04208-002, Brazil
CEPIC - Centro Paulista de Investigação Clínica e Serviços Médicos
São Paulo, São Paulo, 04266-010, Brazil
Hospital das Clínicas da Faculdade de Medicina da USP
São Paulo, São Paulo, 05403-000, Brazil
Incor - Instituto do Coração - HCFMUSP
São Paulo, São Paulo, 05403-000, Brazil
IMC - Instituto de Moléstias Cardiovasculares Tatuí
Tatuí, São Paulo, 18270-170, Brazil
Santa Casa de Votuporanga
Votuporanga, São Paulo, 15500-003, Brazil
MHAT 'Puls' AD
Blagoevgrad, 2700, Bulgaria
MHAT - Blagoevgrad, EOOD
Blagoevgrad, 2700, Bulgaria
MHAT "Yuliya Vrevska - Byala", EOOD
Byala, 7100, Bulgaria
MHAT-Haskovo, AD
Haskovo, 6300, Bulgaria
MHAT "Higia", AD - Pazardzhik
Pazardzhik, 4400, Bulgaria
MHAT - Pazardzhik AD
Pazardzhik, 4400, Bulgaria
MHAT "Sv. Pantaleymon - Pleven", OOD
Pleven, 5800, Bulgaria
SHATC Pleven EAD
Pleven, 5800, Bulgaria
UMHAT 'Dr. Georgi Stranski', EAD
Pleven, 5800, Bulgaria
UMHAT "Sv. Georgi", EAD
Plovdiv, 4000, Bulgaria
UMHAT "Kaspela", EOOD
Plovdiv, 4002, Bulgaria
MC Rusemed ltd.
Rousse, 7013, Bulgaria
Diagnostic Consultative Center II - Sofia OOD
Sofia, 1040, Bulgaria
Fifth MHAT - Sofia EAD
Sofia, 1233, Bulgaria
NMTH "Tsar Boris III"
Sofia, 1233, Bulgaria
MHAT - "National Heart Hospital" EAD
Sofia, 1309, Bulgaria
MHAT "Lyulin", EAD
Sofia, 1336, Bulgaria
Acibadem City Clinic Tokuda Hospital Ead
Sofia, 1407, Bulgaria
MC Start - d-r Todor Dimitrov EOOD
Sofia, 1408, Bulgaria
DCC "Alexandrovska", EOOD
Sofia, 1431, Bulgaria
UMHAT "Alexandrovska" EAD
Sofia, 1431, Bulgaria
UMHAT 'Tsaritsa Yoanna - ISUL', EAD
Sofia, 1527, Bulgaria
Fourth MHAT - Sofia EAD
Sofia, 1606, Bulgaria
Diagnostic Consultation Center CONVEX EOOD
Sofia, 1680, Bulgaria
Medical Center Kalimat
Sofia, 1680, Bulgaria
UMHAT 'Sveta Anna' AD
Sofia, 1750, Bulgaria
MC "Synexus - Sofia", EOOD
Sofia, 1784, Bulgaria
UMHAT "SofiaMed", OOD
Sofia, 1797, Bulgaria
MC "Orfey", EOOD
Stara Zagora, 6000, Bulgaria
SHATC "Cardiolife", OOD
Varna, 9000, Bulgaria
SHATC - Varna, EOOD
Varna, 9002, Bulgaria
MHAT "Sv. Panteleymon", AD
Yambol, 8600, Bulgaria
LMC Clinical Research Inc. (Calgary)
Calgary, Alberta, T2H 2G4, Canada
ALTA Clinical Research Inc.
Edmonton, Alberta, T5A 4L8, Canada
Royal Alexandra Hospital, CK Hui Heart Centre
Edmonton, Alberta, T5H 3V9, Canada
The Bailey Clinic
Red Deer, Alberta, T4N 6V7, Canada
Fraser Clinical Trials Inc.
New Westminster, British Columbia, V3L 3W4, Canada
Surrey Memorial Hospital
Surrey, British Columbia, V3V 0C6, Canada
BC Diabetes As Operated by Dr. TG Elliott, Inc.
Vancouver, British Columbia, V5Y 3W2, Canada
Discovery Clinical Services Ltd.
Victoria, British Columbia, V8T 5G4, Canada
Saint Boniface General Hospital
Winnipeg, Manitoba, R2H 2A6, Canada
Rivergrove Medical Clinic
Winnipeg, Manitoba, R2V 4W3, Canada
Winnipeg Clinic
Winnipeg, Manitoba, R3A 1R9, Canada
Health Sciences Centre
St. John's, Newfoundland and Labrador, NL A1B 3V6, Canada
LMC Clinical Research Inc. (Barrie)
Barrie, Ontario, L4N 7L3, Canada
LMC Clinical Research Inc. (Brampton)
Brampton, Ontario, L6S 0C9, Canada
Aggarwal and Associates Ltd
Brampton, Ontario, L6T 0G1, Canada
JBN Medical Diagnostic Services Inc.
Burlington, Ontario, L7M 4Y1, Canada
LMC Clinical Research dba Manna Research Inc. Burlington North
Burlington, Ontario, L7M 4Y1, Canada
Cambridge Cardiac Care Centre
Cambridge, Ontario, N1R 6V6, Canada
Joanne F. Liutkus Medicine Professional Corporation
Cambridge, Ontario, N1R 7L6, Canada
Saul Vizel Professional Medicine Corporation
Cambridge, Ontario, N1R 7R1, Canada
LMC Clinical Research Inc. (Thornhill)
Concord, Ontario, L4K 4M2, Canada
LMC Clinical Research Inc. (Etobicoke)
Etobicoke, Ontario, M9R 4E1, Canada
Janik Research
Greater Sudbury, Ontario, P3E 5M4, Canada
Dawson Road Family Medical Clinic
Guelph, Ontario, N1H 1B1, Canada
LMC Clinical Research Inc. (Ottawa)
Nepean, Ontario, K2J 0V2, Canada
LMC Clinical Research Inc. (Oakville)
Oakville, Ontario, L6M1M1, Canada
James Cha, MD
Oshawa, Ontario, L1J 2K1, Canada
The Ottawa Hospital - Riverside Campus
Ottawa, Ontario, K1H 7W9, Canada
Kawartha Cardiology Clinical Trials
Peterborough, Ontario, K9J 0B2, Canada
Scarborough Cardiology Research
Scarborough Village, Ontario, M1E 5E9, Canada
Humber River Hospital
Toronto, Ontario, M3M 0B2, Canada
LMC Clinical Research Inc. (Bayview)
Toronto, Ontario, M4G 3E8, Canada
St. Michael's Hospital
Toronto, Ontario, M5B 1W8, Canada
LMC Clinical Research dba Manna Research Inc. Toronto
Toronto, Ontario, M9W 4L6, Canada
Ecogene-21
Chicoutimi, Quebec, G7H 7K9, Canada
ViaCar Recherche Clinique Inc
Greenfield Park, Quebec, J4V 2G8, Canada
Clinique de Cardiologie de Levis
Lévis, Quebec, G6V 4Z5, Canada
Centre de Dépistage et Recherche Cardiovasculaire Rive-Sud
Longueuil, Quebec, J4M 2X1, Canada
LMC Clinical Research dba Manna Research Inc. Mirabel
Mirabel, Quebec, J7J 2K8, Canada
Clinique Santé Cardio MC
Montreal, Quebec, H1T 3Y7, Canada
CHUM Hôtel-Dieu
Montreal, Quebec, H2W 1T8, Canada
Applied Medical Informatics Research Inc.
Montreal, Quebec, H4A 3T2, Canada
Recherche Clinique Sigma Inc.
Québec, Quebec, G1G 3Y8, Canada
Clinique Médicale St-Louis (Recherche) inc d/b/a/ Centre de Recherche Saint-Louis
Québec, Quebec, G1W 4R4, Canada
ALPHA Recherche Clinique
Québec, Quebec, G3K 2P8, Canada
Recherche Médicale St-Jérôme Inc.
Saint-Jérôme, Quebec, J7Z 5T3, Canada
LMC Clinical Research Inc. (Montreal)
Saint-Laurent, Quebec, H4T 1Z9, Canada
Centre Medical des Carrieres
Saint-Marc-des-Carrieres, Quebec, G0A 4B0, Canada
DIEX Recherche Quebec Inc.
Québec, G1N 4V3, Canada
Institut Universitaire de Cardiologie et de Pneumologie de Quebec
Québec, G1V 4G5, Canada
Clinique des maladies Lipidiques de Quebec
Québec, G1V 4M6, Canada
Centro de Investigacion Medico Asistencial S.A.S
Barranquilla, 080020, Colombia
IPS Centro Cientifico Asistencial S.A.S
Barranquilla, 080020, Colombia
Dexa Diab Servicios Médicos Limitada.
Bogotá, 110221, Colombia
Solano y Terront Servicios Médicos Ltda.
Bogotá, 110221, Colombia
Centro Cardiovascular Aristides Sotomayor Santa Lucia S.A.S. - IPS ASTALUC S.A.S. IPS
Cartagena, 130010, Colombia
Fundación Centro de Investigaciones Biomédicas Riescard
Espinal, 00000, Colombia
Fundación Oftalmológica de Santander - FOSCAL
Floridablanca, 681004, Colombia
Centro de Investigación Clínica CIC
Medellín, 050021, Colombia
Medicentrum Beroun spol. s.r.o.
Beroun, 266 01, Czechia
Nemocnice Milosrdnych bratri
Brno, 639 00, Czechia
Fakultni nemocnice u sv. Anny v Brne
Brno, 65691, Czechia
EDUMED s.r.o
Broumov, 550 01, Czechia
Poliklinika Chocen a.s.
Choceň, 56501, Czechia
Ordinace pro choroby srdce s.r.o.
Chomutov, 430 02, Czechia
MUDr. Jan Hubac s.r.o.
Chrudim, 537 01, Czechia
Nemocnice Havlickuv Brod p.o.
Havlíčkův Brod, 580 22, Czechia
Kardio-Pisova s.r.o.
Hradec Králové, 500 02, Czechia
MUDr. Tomas Edelsberger
Krnov, 794 01, Czechia
EDUMED s.r.o
Náchod, 547 01, Czechia
Agentura Science Pro Spol. s.r.o.
Olomouc, 772 00, Czechia
PreventaMed s.r.o.
Olomouc, 77900, Czechia
CCR Ostrava s.r.o.
Ostrava, 702 00, Czechia
MUDr. Jan KVASNICKA CSc. Angiologie kardiologie a interna
Prague, 101 00, Czechia
Nemocnice na Frantisku
Prague, 110 00, Czechia
Synexus Czech s.r.o.
Prague, 120 00, Czechia
Vseobecna fakultni nemocnice v Praze
Prague, 128 00, Czechia
Corintez s.r.o.
Prague, 158 00, Czechia
ResTrial s.r.o.
Prague, 18100, Czechia
MUDr.Eva Mandakova MBA
Rakovník, 269 01, Czechia
Nemocnice Slany
Slaný, 274 01, Czechia
AeskuLab k.s.
Teplice, 415 01, Czechia
Kardiologicka ambulance MUDr. Ferkl s.r.o.
Trutnov, 541 01, Czechia
Clinical Trials Services s.r.o
Uherské Hradiště, 68601, Czechia
MUDr. Nina Zemkova s.r.o.
Uherské Hradiště, 68601, Czechia
Bioclinica
Aalborg, 9000, Denmark
Ålborg Universitets Hospital
Aalborg, 9100, Denmark
Aarhus University Hospital
Aarhus, 8200, Denmark
Bioclinica
Ballerup Municipality, 2750, Denmark
Amager-Hvidovre Hospital
Copenhagen S, 2300, Denmark
Sydvestjyds Sygehus Esbjerg
Esbjerg, 6700, Denmark
Amager-Hvidovre Hospital
Glostrup Municipality, 2600, Denmark
Herlev og Gentofte Hospital
Hellerup, 2900, Denmark
Herlev og Gentofte Hospital
Herlev, 2730, Denmark
Regionshospitalet Herning-Hospitalsenheden Vest
Herning, 7400, Denmark
Holbæk Sygehus
Holbæk, 4300, Denmark
Sjællands Universitetshospital
Roskilde, 4000, Denmark
OUH
Svendborg, 5700, Denmark
Bioclinica
Vejle, 7100, Denmark
CHU Tours - Hôpital Trousseau
Chambray-lès-Tours, Indre Et Loire, 37170, France
CHU Nantes - Hopital Nord Laënnec
Nantes, Loire Atlantique, 44093, France
Hôpital Bichat - Claude Bernard
Paris, Paris, 75877, France
Universitaetsklinikum Freiburg
Freiburg im Breisgau, Baden-Wurttemberg, 79106, Germany
Praxis fuer Praevention und Therapie
Villingen-Schwenningen, Baden-Wurttemberg, 78048, Germany
Gemeinschaftspraxis Dr. Klein/ Minnich
Künzing, Bavaria, 94550, Germany
Klinikum der Universitaet Muenchen
Munich, Bavaria, 80336, Germany
Deutsches Herzzentrum Muenchen
Munich, Bavaria, 80636, Germany
GP Dr. Haggenmiller, PD Dr. Michael Jeserich
Naumburg, Bavaria, 90402, Germany
ZKS-Südbrandenburg -center for clinical studies Südbrandenburg GmbH
Elsterwerda, Brandenburg, 04910, Germany
Neurologische Praxis Dr. Schoell & Kollegen
Bad Homburg, Hesse, 61348, Germany
Synexus Clinical Research GmbH
Frankfurt am Main, Hesse, 60313, Germany
ClinPhenomics GmbH & Co KG
Frankfurt am Main, Hesse, 60596, Germany
Klinische Forschung Schwerin GmbH
Schwerin, Mecklenburg-Vorpommern, 19055, Germany
Synexus Clinical Research GmbH
Bochum, North Rhine-Westphalia, 44787, Germany
Gemeinschaftspraxis Diabeteszentrum Dortmund Dr.med. Klaus Busch
Dortmund, North Rhine-Westphalia, 44137, Germany
Kardiologische Praxis Gemeinschaftspraxis
Dortmund, North Rhine-Westphalia, 44137, Germany
St. Johannes Hospital
Dortmund, North Rhine-Westphalia, 44137, Germany
Klinikum Bielefeld gem. GmbH
Dortmund, North Rhine-Westphalia, 44139, Germany
Zentrum fuer Praevention und Rehabilitation
Siegen, North Rhine-Westphalia, 57072, Germany
Synexus Clinical Research GmbH
Leipzig, Saxony, 04103, Germany
Gemeinschaftspraxis Dr. Taeschner / Dr. Bonigut
Leipzig, Saxony, 04249, Germany
Dr. Uwe Böckmann / Birgit Jacobs - Diabeteszentrum Neumünster
Neumünster, Schleswig-Holstein, 24534, Germany
RED - Institut GmbH
Oldenburg in Holstein, Schleswig-Holstein, 23758, Germany
Katholisches Krankenhaus "St. Johann Nepomuk"
Erfurt, Thuringia, 99097, Germany
Diabetespraxis Prenzlauer Allee
Berlin, 10409, Germany
Institut fuer klinische Forschung und Entwicklung Berlin GmbH
Berlin, 10437, Germany
Studienzentrum Rankestrasse
Berlin, 10789, Germany
Synexus Clinical Research GmbH
Berlin, 12627, Germany
Gemeinschaftspraxis fuer innere Medizin und Diabetologie
Hamburg, 22607, Germany
Lausmed Kft.
Baja, 6500, Hungary
Principal SMO Kft.
Baja, 6500, Hungary
DRC Gyogyszervizsgalo Kozpont Kft.
Balatonfüred, 8230, Hungary
Bekes Megyei Kozponti Korhaz Dr. Rethy Pal Tagkorhaz
Békéscsaba, 5600, Hungary
Belgyogyaszati es Kardiologiai Maganrendelo
Békéscsaba, 5600, Hungary
Clinexpert Kft.
Budapest, 1033, Hungary
Synexus Magyarorszag Kft.
Budapest, 1036, Hungary
CSALADGYOGYASZ Kft.
Budapest, 1083, Hungary
Semmelweis Egyetem
Budapest, 1083, Hungary
Borvo Clinic Kft.
Debrecen, 4025, Hungary
Debreceni Egyetem
Debrecen, 4032, Hungary
Meditoll Kft.
Gödöllő, 2100, Hungary
Bekes Megyei Kozponti Korhaz Pandy Kalman Tagkorhaza
Gyula, 5700, Hungary
Synexus Magyarorszag Egeszsegugyi Szolgaltato Kft.- Gyula DRS
Gyula, 5700, Hungary
BKS Research Kft.
Hatvan, 3000, Hungary
Z+P MED Egeszsegugyi, Kereskedelmi es Szolgaltato Bt.
Kalocsa, 6300, Hungary
Somogy Megyei Kaposi Mor Oktato Korhaz
Kaposvár, 7400, Hungary
Selye Janos Korhaz
Komárom, 2900, Hungary
IPR Hungary Kft.
Miskolc, 3530, Hungary
Kanizsai Dorottya Korhaz
Nagykanizsa, 8800, Hungary
Medifarma-98 Kft.
Nyíregyháza, 4400, Hungary
BORBANYA PRAXIS Kft.
Nyíregyháza, H-4405, Hungary
Dr. Nagy Laszlo Kardiologiai Maganrendeles
Orosháza, 5900, Hungary
Da Vinci Maganklinika
Pécs, 7635, Hungary
Tolna Megyei Balassa Janos Korhaz
Szekszárd, 7100, Hungary
Fejer Megyei Szent Gyorgy Egyetemi Oktato Korhaz
Székesfehérvár, 8000, Hungary
Csolnoky Ferenc Korhaz
Veszprém, 8200, Hungary
Zala Megyei Szent Rafael Korhaz
Zalaegerszeg, 8900, Hungary
Vijaya Super Speciality Hospital
Nellore, Andhra Pradesh, 524001, India
GNRC Hospital
Guwahati, Assam, 781006, India
Ahmedabad Bariatrics and Cosmetics Pvt Ltd.
Ahmedabad, Gujarat, 380015, India
S. A. L. Hospital & Medical Institute
Ahmedabad, Gujarat, 380054, India
DDMM Heart Institute
Nadiād, Gujarat, 387002, India
Shri B. D. Mehta Mahavir Heart Institute
Surat, Gujarat, 395002, India
BAPS Pramukhswami Hospital
Surat, Gujarat, 395009, India
Sterling Hospital
Vadodara, Gujarat, 390007, India
Rhythm Heart Institute
Vadodara, Gujarat, 391740, India
Medanta The Medicity
Gurgaon, Haryana, 122001, India
Fortis Hospitals Ltd.
Bangalore, Karnataka, 560052, India
K.L.E. Society's Dr. Prabhakar Kore Hospital and Medical Research Centre
Belagavi, Karnataka, 590010, India
JSS Hospital
Mysuru, Karnataka, 570004, India
Medical College
Thiruvananthapuram, Kerala, 695 011, India
Meditrina Institute Of Medical Sciences
Nagpur, Maharashtra, 440010, India
Supe Heart & Diabetes Hospital & Research Centre
Nashik, Maharashtra, 422002, India
7-Orange Hospital
Pimpri-Chinchwad, Maharashtra, 411033, India
Shree Multispecialty Hospital
Pune, Maharashtra, 411006, India
King Edward Memorial Hospital Research Centre
Pune, Maharashtra, 411011, India
Aashirwad Hospital
Ulhasnagar, Maharashtra, 421001, India
Loknayak Hospital
New Delhi, National Capital Territory of Delhi, 110002, India
Sir Gangaram Hospital
New Delhi, National Capital Territory of Delhi, 110060, India
Fortis Flight Lieutenant Rajan Dhall Hospital
New Delhi, National Capital Territory of Delhi, 110070, India
Institute of Medical Sciences and SUM Hospital
Bhubaneshwar, Odisha, 751003, India
Eternal Heart Care Centre
Jaipur, Rajasthan, 302020, India
SRM Institutes for Medical Sciences
Chennai, Tamil Nadu, 600026, India
Institute of Cardiovascular Diseases Madras Medical Mission
Chennai, Tamil Nadu, 600037, India
KRM Hospital & Research Centre
Lucknow, Uttar Pradesh, 226010, India
Galaxy Hospital
Varanasi, Uttar Pradesh, 221010, India
IPGMER and SSKM Hospital
Kolkata, West Bengal, 700020, India
Maharaja Agrasen Hospital
Delhi, 110052, India
HaEmek Medical Center
Afula, 18101, Israel
Bnai Zion Medical Center
Haifa, 31048, Israel
Rambam Health Care Center
Haifa, 3109601, Israel
The Lady Davis Carmel Medical Center
Haifa, 34362, Israel
Wolfson Medical Center
Holon, 58100, Israel
Shaare Zedek Medical Center
Jerusalem, 91031, Israel
Hadassah University Hospital - Ein Kerem
Jerusalem, 91120, Israel
Galilee Medical Center
Nahariya, 2210001, Israel
Rabin Medical Center-Beilinson Campus
Petah Tikva, 49100, Israel
Chaim Sheba Medical Center
Ramat Gan, 52621, Israel
Kaplan Medical Center
Rehovot, 7610001, Israel
Ziv Medical Center
Safed, 13100, Israel
Tel Aviv Sourasky Medical Center
Tel Aviv, 6423906, Israel
Diabetes Medical Center
Tel Aviv, 6937947, Israel
Aichi Medical University Hospital
Nagakute-shi, Aichi-ken, 480-1195, Japan
JOHAS Chubu Rosai Hospital
Nagoya, Aichi-ken, 455-8530, Japan
Kojunkai Daido Clinic
Nagoya, Aichi-ken, 457-8511, Japan
NHO Nagoya Medical Center
Nagoya, Aichi-ken, 460-0001, Japan
National Center For Geriatrics And Gerontology
Obu-shi, Aichi-ken, 474-8511, Japan
Fujita Health University Hospital
Toyoake-shi, Aichi-ken, 470-1192, Japan
Chiba University Hospital
Chiba, Chiba, 260-8677, Japan
Kioroshikai Chibanishi General Hospital
Matsudo-shi, Chiba, 270-2251, Japan
Seikeikai New Tokyo Heart Clinic
Matsudo-shi, Chiba, 271-0077, Japan
Ehime Prefectural Central Hospital
Matsuyama, Ehime, 790-0024, Japan
Fukuoka University Hospital
Fukuoka, Fukuoka, 814-0180, Japan
Fukuoka Tokushukai Hospital
Kasuga-shi, Fukuoka, 816-0864, Japan
Steel Memorial Yawata Hospital
Kitakyushu-shi, Fukuoka, 805-8508, Japan
NHO Fukuoka Higashi Medical Center
Koga-shi, Fukuoka, 811-3195, Japan
Chiyukai Fukuoka Shinmizumaki Hospital
Onga-gun, Fukuoka, 807-0051, Japan
Southern Tohoku Medical Clinic
Koriyama-shi, Fukushima, 963-8052, Japan
Hoshi General Hospital
Koriyama-shi, Fukushima, 963-8501, Japan
Nakahama Heart Clinic
Fuchu-shi, Hiroshima, 726-0013, Japan
Nippon Kokan Fukuyama Hospital
Fukuyama-shi, Hiroshima, 721-0927, Japan
NHO Higashihiroshima Medical Center
Higashihiroshima-shi, Hiroshima, 739-0041, Japan
Miyanosawa Clinic of Internal Medicine and Cardiology
Sapporo, Hokkaido, 063-0826, Japan
Tanaka Cardiology Clinic
Hitachi-Naka, Ibaraki, 312-0032, Japan
Nakakinen Clinic Medical Corporation Kensei-kai
Naka, Ibaraki, 311-0113, Japan
Public Central Hospital of Matto Ishikawa
Hakusan-shi, Ishikawa-ken, 924-8588, Japan
NHI Komatsu Municipal Hospital
Komatsu-shi, Ishikawa-ken, 923-8560, Japan
Kuonkai Kamata Medical Clinic
Morioka, Iwate, 020-0866, Japan
Iwate Medical University Uchimaru Medical Center Hospital
Morioka, Iwate, 020-8505, Japan
Josuikai Olive Takamatsu Medical Clinic
Takamatsu, Kagawa-ken, 760-0076, Japan
Sohken Yamamoto Clinic
Sagamihara-shi, Kanagawa, 252-0311, Japan
NHO Yokohama Medical Center
Yokohama, Kanagawa, 245-8575, Japan
Kumamoto University Hospital
Kumamoto, Kumamoto, 860-8556, Japan
Ryubokai Higashi Diabetes and Cardiovascular Clinic
Tamana-shi, Kumamoto, 865-0016, Japan
Ijinkai Takeda General Hospital
Kyoto, Kyoto, 601-1495, Japan
Kyoto University Hospital
Kyoto, Kyoto, 606-8507, Japan
Rakuwakai Otowa Hospital
Kyoto, Kyoto, 607-8062, Japan
Sato Hospital
Osaki-shi, Miyagi, 989-6143, Japan
Tohoku Kosai Hospital
Sendai, Miyagi, 980-0803, Japan
Sendai Kousei Hospital
Sendai, Miyagi, 980-0873, Japan
Keiwakai Oita Oka Hospital
Ōita, Oita Prefecture, 870-0192, Japan
Okayama University Hospital
Okayama, Okayama-ken, 700-8558, Japan
Okinawa Tokushukai Chubu Tokushukai Hospital
Nakagami-gun, Okinawa, 901-2393, Japan
Iwasaki Naika Clinic
Higashiosaka-shi, Osaka, 577-0802, Japan
Takekawa Naika Clinic
Higashiosaka-shi, Osaka, 577-0803, Japan
Rinku General Medical Center
Izumisano, Osaka, 598-8577, Japan
Shiraiwa Medical Clinic
Kashiwara-shi, Osaka, 582-0005, Japan
Tokushukai Kishiwada Tokushukai Hospital
Kishiwada-shi, Osaka, 596-8522, Japan
Kansai Electric Power Hospital
Osaka, Osaka, 553-0003, Japan
National Cerebral and Cardiovascular Center
Suita-shi, Osaka, 564-8565, Japan
Senrichuo Ekimae Clinic
Toyonaka-shi, Osaka, 560-0082, Japan
IMS Miyoshi General Hospital
Iruma-gun, Saitama, 354-0041, Japan
Sugiura Clinic
Kawaguchi-shi, Saitama, 332-0012, Japan
Sanyukai Saino Clinic
Tokorozawa-shi, Saitama, 359-1141, Japan
NHO Saitama National Hospital
Wako-shi, Saitama, 351-0102, Japan
Shiga University of Medical Science Hospital
Ōtsu, Shiga, 520-2192, Japan
NHO Hamada Medical Center
Hamada-shi, Shimane, 697-8511, Japan
Jichi Medical University Hospital
Shimotsuke-shi, Tochigi, 329-0498, Japan
Juntendo University Hospital
Bunkyō City, Tokyo-To, 113-8431, Japan
Fukuwa Clinic
Chūōku, Tokyo-To, 103-0027, Japan
Tokyo-Eki Center-Building Clinic
Chūōku, Tokyo-To, 103-0027, Japan
Nomura Clinic
Itabashi-ku, Tokyo-To, 173-0004, Japan
Hosoda Clinic
Katsushika-ku, Tokyo-To, 124-0021, Japan
Toyukai Yutenji Medical Clinic (Yutenji Naika)
Meguro-ku, Tokyo-To, 153-0053, Japan
Shinjuku Research Park Clinic
Shinjuku-ku, Tokyo-To, 169-0073, Japan
Yamaguchi University Hospital
Ube-shi, Yamaguchi, 755-8505, Japan
Centro de Investigacion Cardiovascular y Metabolica
Tijuana, Baja California Norte, 22500, Mexico
Centro de Investigacion Clinica del Pacifico, S.A. de C.V.
Acapulco de Juárez, Guerrero, 39670, Mexico
Cardiologia Clinica e Intervencionista
Guadalajara, Jalisco, 44670, Mexico
Centro de Investigacion Medica de Occidente, S.C.
Zapopan, Jalisco, 45116, Mexico
Phytomedicamenta S.A. de C.V.
Mexico City, Mexico City, 03100, Mexico
Health Pharma Professional Research S.A. de C.V.
Mexico City, Mexico City, 03810, Mexico
Centro de Atención e Investigación en Factores de Riesgo Cardiovascular Omega S.C.
Mexico City, Mexico City, 06700, Mexico
Instituto Nacional de Ciencias Médicas y Nutricion Dr. Salvador Zubiran
Mexico City, Mexico City, 14080, Mexico
Mentrials S.A. de C.V.
Mexico City, Mexico City, 67000, Mexico
Instituto de Diabetes, Obesidad y Nutrición S.C.
Cuautla, Morelos, 62746, Mexico
Universidad Autonoma de Nuevo Leon, Hospital Universitario Dr. Jose Eleuterio Gonzalez
Monterrey, Nuevo León, 64460, Mexico
Centro Medico San Francisco
Monterrey, Nuevo León, 64710, Mexico
Unidad Medica para la Salud Integral
San Nicolás de los Garza, Nuevo León, 66465, Mexico
Centro Integral Medico SJR S.C.
San Juan del Río, Querétaro, 76800, Mexico
Centro de Estudios de Investigacion Metabolicos y Cardiovasculares S.C.
Madero, Tamaulipas, 89440, Mexico
Centro de Investigacion Cardiometabolica de Aguascalientes S.A de C.V
Aguascalientes, 20230, Mexico
Investigacion En Salud Y Metabolismo S.C.
Chihuahua City, 31237, Mexico
Sociedad de Metabolismo y Corazon S.C
Veracruz, 91900, Mexico
Noordwest Ziekenhuisgroep
Alkmaar, 1815 JD, Netherlands
Ziekenhuisgroep Twente, Almelo
Almelo, 7609 PP, Netherlands
Meander Medisch Centrum
Amersfoort, 3813 TZ, Netherlands
Ziekenhuis Amstelland
Amstelveen, 1186 AM, Netherlands
BovenlJ Ziekenhuis
Amsterdam, 1034 CS, Netherlands
Amsterdam UMC, Locatie AMC
Amsterdam, 1105 AZ, Netherlands
Gelre ziekenhuizen, locatie Lukas
Apeldoorn, 7334 DZ, Netherlands
Rijnstate
Arnhem, 6815 AD, Netherlands
Deventer Ziekenhuis
Deventer, 7416 SE, Netherlands
Albert Schweitzer Ziekenhuis, Dordwijk
Dordrecht, 3318 AT, Netherlands
Gelderse Vallei Ziekenhuis, Ede
Ede, 6716 RP, Netherlands
Catharina Ziekenhuis Eindhoven
Eindhoven, 5623 EJ, Netherlands
Spaarne Gasthuis, Hoofddorp
Haarlem, 2035 RC, Netherlands
Zuyderland Medisch Centrum - Heerlen
Heerlen, 6419 PC, Netherlands
Huisartsenpraktijk Gorecht
Hoogezand, 9603 AE, Netherlands
Quality Care Research
Kloosterhaar, 7694 AC, Netherlands
Leids Universitair Medisch Centrum
Leiden, 2333 ZA, Netherlands
Bravis Ziekenhuis, Roosendaal
Roosendaal, 4708 AE, Netherlands
Maasstad Ziekenhuis, Zuider
Rotterdam, 3079 DZ, Netherlands
Ikazia Ziekenhuis
Rotterdam, 3083 AN, Netherlands
Albert Schweitzer Ziekenhuis, Zwijndrecht
Sliedrecht, 3331 LZ, Netherlands
Haga Ziekenhuis
The Hague, 2545 AA, Netherlands
Bernhoven Uden
Uden, 5406 PT, Netherlands
UMC Utrecht
Utrecht, 3508 GA, Netherlands
Diakonessenhuis, Utrecht
Utrecht, 3582 KE, Netherlands
Maxima Medisch Centrum
Veldhoven, 5504 DB, Netherlands
VieCuri Medisch Centrum
Venlo, 5912 BL, Netherlands
NZOZ Centrum Medyczne KERmed
Bydgoszcz, 85-231, Poland
KARDIOMED Janczska Kociwska Ostki PodckaRekrzSp
Elblag, 82-300, Poland
Poradnia Kardiologiczna Jarosław Jurowiecki
Gdansk, 80-286, Poland
Synexus Polska SCM Sp. z o.o. Gdansku
Gdansk, 80-382, Poland
Uniwersyteckie Centrum Kliniczne
Gdansk, 80-952, Poland
Indywidualna Specjalistyczna Praktyka Lekarska w Dziedzinie Kardiologii lek. med. Krzysztof Cymerman
Gdynia, 81-157, Poland
Synexus Polska Sp. z o.o. Oddzial w Gdyni
Gdynia, 81-537, Poland
Samodzielny Publiczny Specjalistyczny Szpital Zachodni im. Jana Pawla II
Grodzisk Mazowiecki, 05-825, Poland
Synexus Polska Sp. z o.o. Oddzial w Katowicach
Katowice, 40-040, Poland
Centrum Medyczne Pratia Katowice II
Katowice, 40-084, Poland
SPSK Nr 7 SUM w Katowicach Gornoslaskie CM im. prof. Leszka Gieca
Katowice, 40-635, Poland
Specjalistyczna Poradnia Kardiologiczna i Nadciśnienia Tętniczego
Kielce, 25-525, Poland
Augustyn Monika
Krakow, 30-363, Poland
Krakowskie Centrum Medyczne Sp. z o.o.
Krakow, 31-501, Poland
Wojewódzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. M. Kopernika w Łodzi
Lodz, 93-513, Poland
NZOZ ALL-MED Centrum Medyczne Specjalistyczne Gabinety Lekarskie
Lodz, 94-048, Poland
Indywidualna Specjalistyczna Praktyka Lekarska
Lodz, 94-255, Poland
KO-MED Centra Kliniczne Lublin II
Lublin, 20-362, Poland
Clinical Best Solutions
Lublin, 20-709, Poland
NZOZ Twoja Przychodnia
Lublin, 20-857, Poland
NZOZ Osrodek Kardiologii Inwazyjnej -Ikardia
Nałęczów, 24-140, Poland
Medicome Sp. z o.o.
Oświęcim, 32-600, Poland
Synexus Polska sp. z o.o. Oddzial w Poznaniu
Poznan, 60-702, Poland
Praktyka Lekarska Ewa Krzyzagorska
Poznan, 61-655, Poland
KO-MED Centra Kliniczne Pulawy
Puławy, 24-100, Poland
NZOZ Przychodnia Specjalistyczna H. Rudzki, A. Wittek
Ruda Śląska, 41-709, Poland
Centrum Medyczne Medyk
Rzeszów, 35-055, Poland
Clinmed Research
Skierniewice, 96-100, Poland
NZOZ Pro-Cordis Sopockie Centrum Bad. Kardiolog.
Sopot, 81-717, Poland
KO-MED Centra Kliniczne Staszow
Staszów, 28-200, Poland
Indywidualna Specjalistyczna Praktyka Lekarska dr n. med. Agnieszka Karczmarczyk Specjalista Chorob
Szczecin, 71-531, Poland
NSZOZ Medicus
Środa Wielkopolska, 63-000, Poland
NBR Polska
Warsaw, 00-465, Poland
Centrum Medyczne Świat Pacjenta
Warsaw, 00-631, Poland
Synexus Polska Sp. z o.o. Oddział w Warszawie
Warsaw, 01-192, Poland
Centrum Zdrowia Tuchow Sp. z o.o.
Wierzchosławice, 33-122, Poland
Synexus Polska Sp. z o.o. Oddział we Wroclawiu
Wroclaw, 50-381, Poland
KO-MED Centra Kliniczne Zamosc
Zamość, 22-400, Poland
VA Medical Center - San Juan
San Juan, 00927-5800, Puerto Rico
S.C. CMI Dr. Pletea Noemi S.R.L
Bacau, 600154, Romania
Cabinet Medical Individual Diabet, Nutritie, Boli Metabolice Dr. Pop Lavinia
Baia Mare, 430222, Romania
S.C Centrul Medical de Diagnostic si Tratament Ambulator Neomed S.R.L
Brasov, 500283, Romania
S.C Clinica Medicala Data Plus S.R.L
Bucharest, 010192, Romania
Spitalul Clinic Colentina
Bucharest, 020125, Romania
Spitalul Clinic de Urgenta "Sfantul Pantelimon"
Bucharest, 021659, Romania
Institutul de Urgenta pentru Boli Cardiovasculare "Prof. Dr. C.C. Iliescu"
Bucharest, 022328, Romania
S.C. Health Net S.R.L
Bucharest, 030088, Romania
S.C Policlinica CCBR S.R.L
Bucharest, 030463, Romania
CMI Dr. Stolea T. Violeta - Medic specialist diabet zaharat, nutritie si boli metabolice
Bucharest, 061072, Romania
S.C. Medcon S.R.L.
Buzău, 120203, Romania
S.C Grandmed S.R.L
Oradea, 410159, Romania
S.C Pelican Impex S.R.L
Oradea, 410469, Romania
S.C. Bella Praxis S.R.L
Pașcani, 705200, Romania
S.C. Diabmed Dr. Popescu Alexandrina S.R.L
Ploieşti, 100163, Romania
CMI Dr Busegeanu Mihaela Magdalena
Ploieşti, 100342, Romania
S.C Mediab S.R.L
Târgu Mureş, 540142, Romania
S.C Medicali's S.R.L
Timișoara, 300359, Romania
Spitalul Clinic Judetean de Urgenta "Pius Brinzeu"
Timișoara, 300723, Romania
SBIH of Arkhangelsk region " First City Clinical hospital n.a. E. E. Volosevich"
Arkhangelsk, 163001, Russia
TSHI "Altay Territorial Cardiologocal dispensary"
Barnaul, 656055, Russia
FSHI "MSU of MoIA of RF of Kemerovo Region"
Kemerovo, 650000, Russia
FSBI "Scientific-research Institute for Complex Problems of cardiovascular disease"
Kemerovo, 650002, Russia
NSIH "Departmental Hospital on Station Kemerovo of OJSC "Russian Railways"
Kemerovo, 650055, Russia
SAIH "Kemerovo Regional Clinical Hospital"
Kemerovo, 650066, Russia
TSBIH "Krasnoyarsk Interdistrict Clinical Hospital of Emergency Medical Care n.a. N.S. Karpovich
Krasnoyarsk, 660062, Russia
SBIH of Moscow "City Clinical Hospital n.a.Bakhrushinykh"
Moscow, 107 014, Russia
SBHI "City Polyclinic #2 of Healthcare department of city of Moscow"
Moscow, 117556, Russia
FSBIH "Central Clinical Hospital of Russian Academy of Sciences"
Moscow, 117593, Russia
FSBI "Central Clinical Hospital with Polyclinic of the Department for Presidential Affairs of the RF
Moscow, 121359, Russia
SBEI HPE "Moscow State Medical and Dentistry University n.a. A. I. Evdokimov" of the MoH of the RF
Moscow, 127473, Russia
SBEI HPE "Moscow State Medical and Dentistry University n.a. A. I. Evdokimov" of the MoH of the RF
Moscow, 129301, Russia
Murmansk Regional Clinical Hospital named after Bayandin
Murmansk, 183047, Russia
SBIH of Novosibirsk Region "Clinical Emergency Hospital #2"
Novosibirsk, 630008, Russia
SBIH of Novosibirsk region "City Clinical Hospital # 19"
Novosibirsk, 630068, Russia
FSBSI "Scientific Research Institute of Therapy and Preventive Medicine"
Novosibirsk, 630089, Russia
LLC "RC Medical"
Novosibirsk, 630091, Russia
BIH of Omsk region "Clinical Medico-Sanitary Unit # 9
Omsk, 644018, Russia
Llc Ultramed
Omsk, 644024, Russia
SBIH of Perm territory " City Clinical Hospital # 2 n.a. Fedor Khristoforovich Gral"
Perm, 614068, Russia
State Budgetary Healthcare Institution Clinical Medical Sani
Perm, 614077, Russia
SHI "Perm Regional Hospital of War Veterans"
Perm, 614097, Russia
City Emergency Hospital #2
Rostov-on-Don, 344068, Russia
CJSC Clinic complex
Saint Petersburg, 190013, Russia
FSBI North-West Federal Medical Research Center n.a. V.A. Almazov of MoH RF
Saint Petersburg, 194156, Russia
SPb SBIH "City Multy-field Hospital # 2"
Saint Petersburg, 194354, Russia
Saint-Petersburg SBHI "City outpatient clinic #28"
Saint Petersburg, 195427, Russia
LLC "Institute of Medical Examinations"
Saint Petersburg, 196084, Russia
Pavlov First Saint Petersburg State Medical University
Saint Petersburg, 197022, Russia
Llc "Medinet"
Saint Petersburg, 197136, Russia
SPb SBIH "Nikolaevskaya Hospital"
Saint Petersburg, 198510, Russia
SPb SBIH "City Pokrovskaya Hospital"
Saint Petersburg, 199106, Russia
LLC Medical Center Mart
Saint Petersburg, 199178, Russia
SIH "Saratov City Clinical Hospital # 2 n.a. V.I. Razumovskiy"
Saratov, 410028, Russia
SPb SBIH "City Hospital # 40 of Kurortnyi region"
Sestroretsk, 197706, Russia
FSBI "Research Institute for Cardiology" of Siberian Branch RAMS
Tomsk, 634012, Russia
SHI "Regional Clinical Hospital"
Tver', 170036, Russia
SHI Ulyanovsk Reg Clinical Hospital
Ulyanovsk, 432063, Russia
Yaroslavl Regional Clinical Hospital of War Veterans
Yaroslavl, 150047, Russia
SEIHPE "Ural SMA of RosZdrav" b.o. LLC "City Hospital #41"
Yekaterinburg, 620026, Russia
Alian s.r.o.
Bardejov, 085 01, Slovakia
Thyreomedical s.r.o.
Bardejov, 08501, Slovakia
Metabol KLINIK s.r.o.
Bratislava, 81108, Slovakia
Galenum, s.r.o.
Bratislava, 821 07, Slovakia
DIAFA s.r.o.
Bratislava, 82102, Slovakia
Diabet, spol. s.r.o.
Bratislava, 82108, Slovakia
Kardiovaskularne centrum, s.r.o.
Bratislava, 83101, Slovakia
Kardiologicka, interna a sonograficka amb. Kardio-Sanus, sro
Bratislava, 84108, Slovakia
MEDISPEKTRUM PLUS s.r.o.
Bratislava, 85101, Slovakia
MUDr. Vladimir Gergel, s.r.o.
Bratislava, 85101, Slovakia
ENDIAMED, s.r.o.
Dolný Kubín, 02601, Slovakia
MEDICUS plus s.r.o.
Komárno, 94501, Slovakia
Human-Care s.r.o.
Košice, 04001, Slovakia
Sukromna interna a kardiologicka ambulancia
Košice, 04001, Slovakia
DIA- Kontrol s.r.o.
Levice, 93401, Slovakia
CELL B, s.r.o.
Levice, 93405, Slovakia
KARDIO 1 s.r.o.
Lučenec, 984 39, Slovakia
IN-DIA s.r.o.
Lučenec, 98401, Slovakia
MUDr. Zuzana Ochodnicka,
Nitra, 94911, Slovakia
Fakultna nemocnica s poliklinikou Nove Zamky
Nové Zámky, 94002, Slovakia
DIABETOL s.r.o.
Prešov, 08001, Slovakia
Medispol s.r.o.
Prešov, 08001, Slovakia
Nemocnica s poliklinikou sv. Barbory Roznava a.s.
Rožňava, 04801, Slovakia
Interna SK s.r.o.
Svidník, 08901, Slovakia
Nemocnica arm. generala L. Svobodu Svidnik, a.s.,
Svidník, 08901, Slovakia
Peter Farkas MD, s.r.o.
Šahy, 93601, Slovakia
Diabetes centrum, s.r.o.
Trenčín, 91101, Slovakia
JAL s.r.o.
Trnava, 91701, Slovakia
MEDIVASA s.r.o.
Žilina, 01001, Slovakia
Cardiology Clinical Research
Alberton, Gauteng, 1449, South Africa
Johese Clinical Research: Unitas
Centurion, Gauteng, 0157, South Africa
Medicross Roodepoort Clinical Research
Johannesburg, Gauteng, 1724, South Africa
Lenasia Clinical Trial Centre
Johannesburg, Gauteng, 1827, South Africa
Wits Clinical Research
Johannesburg, Gauteng, 2013, South Africa
Clinresco Centres (Pty) Ltd
Kempton Park, Gauteng, 1619, South Africa
Synexus SA - Stanza Clinical Research Centre
Mamelodi East, Gauteng, 0122, South Africa
Seeber, M
Pretoria, Gauteng, 0002, South Africa
Emmed Research
Pretoria, Gauteng, 0084, South Africa
Synexus SA Watermeyer Clinical Research Centre
Pretoria, Gauteng, 0184, South Africa
Johese Clinical Research: Midstream
Pretoria, Gauteng, 1692, South Africa
Limpopo Clinical Research Initiative
Thabazimbi, Limpopo, 0380, South Africa
Dr AA Mahomed Medical Centre
Moloto South, Mpumalanga, 1022, South Africa
Synexus Helderberg Clinical Research Centre
Cape Town, Western Cape, 7130, South Africa
Corbod Research
Cape Town, Western Cape, 7500, South Africa
Tread Research
Cape Town, Western Cape, 7500, South Africa
Tiervlei Trial Centre
Cape Town, Western Cape, 7530, South Africa
Cape Town Medical Research Centre
Cape Town, Western Cape, 7580, South Africa
Paarl Research Centre
Cape Town, Western Cape, 7646, South Africa
Groote Schuur Hospital Lipid Laboratory
Cape Town, Western Cape, 7925, South Africa
Dr JM Engelbrecht Practice
Somerset West, Western Cape, 7130, South Africa
Helderberg Research Institute
Somerset West, Western Cape, 7130, South Africa
Hospital Universitari Germans Trias i Pujol
Badalona, Barcelona, 08916, Spain
Hospital Virgen del Camino
Sanlúcar de Barrameda, Cádiz, 11540, Spain
Hospital Universitario Reina Sofia
Córdoba, Córdoba, 14004, Spain
Complejo Hospitalario Universitario A Coruña
A Coruña, La Coruña, 15006, Spain
Complejo Hospitalario Universitario de Santiago
Santiago de Compostela, La Coruña, 15706, Spain
Hospital Virgen del Mar
Almería, 04120, Spain
Hospital del Mar
Barcelona, 08003, Spain
Hospital Quironsalud Barcelona
Barcelona, 08023, Spain
Hospital de la Santa Creu i Sant Pau
Barcelona, 08025, Spain
Hospital Universitari Vall d'Hebron
Barcelona, 08035, Spain
Hospital Universitario Ramon y Cajal
Madrid, 28034, Spain
Hospital Regional Universitario de Malaga
Málaga, 29010, Spain
Nuevas tecnologías en Diabetes y Endocrinología
Seville, 41003, Spain
Hospital Quironsalud Infanta Luisa
Seville, 41010, Spain
Hospital Universitario Virgen Macarena
Seville, 41071, Spain
Cherkasy Regional Cardiological Center
Cherkasy, 18009, Ukraine
CI Cherkasy RH of Cherkasy Regional Council
Cherkasy, 18009, Ukraine
CMI CCH#3 Dep of Ther# w the beds of card profile HSEI of UBSMU
Chernivtsi, 58000, Ukraine
RCI Chernivtsi Regional Endocrinology Center Policlinic Dept SHEI of UBSMU
Chernivtsi, 58022, Ukraine
CI Dnipropetrovsk City Cl Hosp #9 of Dniprop Reg Council SI DMA of MOH of Ukr Ch of Endocrinology
Dnipro, 49000, Ukraine
Medical Center of Limited Liability Company Medical Center Clinic of Family Medicine
Dnipro, 49038, Ukraine
Regional CH Dept of Endocrinology SHEI Ivano-Frankivsk NMU
Ivano-Frankivsk, 76008, Ukraine
CI Ivano-Frankivsk Reg Cl Card Center Dept of Chronic Ischemic Heart Dis SHEI Ivano-Frank NMU
Ivano-Frankivsk, 76018, Ukraine
Ivano-Frankivsk CCH Dept of Therapy #1 SHEI Ivano-Frankivsk NMU
Ivano-Frankivsk, 76018, Ukraine
CHI Kharkiv City Student Hosp Therap dept Nat Pharm Univer
Kharkiv, 61002, Ukraine
CNE Prof. O.O. Shalimov Kharkiv City Clinical Hospital #2 KCC
Kharkiv, 61037, Ukraine
GI L.T.Malaya Therapy National Institute of the NAMS of Ukraine
Kharkiv, 61039, Ukraine
State Institution LT Malaya Inst. of Ther. of AMS of Ukraine
Kharkiv, 61039, Ukraine
Railway Transport Kharkiv CH #1 of Healthcare Center Branch of PJSC Ukr Railway
Kharkiv, 61103, Ukraine
Railway Transport Kharkiv CH#1 of Healthcare Center Branch of PJSC Ukrainian Railway
Kharkiv, 61103, Ukraine
MC Doctor Alex Dept of General Practice-Family Medicine Kharkiv MA of PGE
Kharkiv, 61106, Ukraine
CNE City Clin Hosp #8 of KCC Dept of Therapy Kharkiv MA of PGE of MOHU
Kharkiv, 61176, Ukraine
CI Ye.Ye.Karabelesh Kherson City Clinical Hosp.
Kherson, 73000, Ukraine
KCCC of Endocr Dept of General Endocrine Pathology O. O. Bogomolets NMU
Kyiv, 01004, Ukraine
Kyiv CCH #12 Dept of Therapy O.O.Bogomolets NMU
Kyiv, 01103, Ukraine
LLC Treatment and Diagnostic Center Adonis Plus
Kyiv, 02002, Ukraine
MC of PHEI Institute of General Practice - Family Medicine
Kyiv, 02002, Ukraine
Medical Center Blagomed Plus LLC
Kyiv, 02081, Ukraine
Med Center 'Ok!Clinic+' of International Institute of Clinical Trials LLC
Kyiv, 02091, Ukraine
MC of Subsidiary Production Unit Med Scient Pract Union Medbud of PJSc Holding Company Kyivmiskbud
Kyiv, 03037, Ukraine
Kyiv CH on Railway Transport #2 of Branch Center of Healthcare Public Company Ukr Railway
Kyiv, 03049, Ukraine
Med Center of Eurolab LLC Policlinic Outpatient Dept O.O.Bogomolets NMU
Kyiv, 03110, Ukraine
SI National Scientific Centre of Radiation Medicine of NAMSU
Kyiv, 03115, Ukraine
SI NSC M.D. Strazhesko Institute of Cardiology of NAMSU
Kyiv, 03680, Ukraine
SI NSС M.D. Strazhesko Institute of Cardiology of NAMSU
Kyiv, 03680, Ukraine
Department of Medical Services and Rehabilitation of State Joint Stock Holding Company Artem
Kyiv, 04050, Ukraine
Medical Center of Limited Liability Company Medical Center Concilium Medical
Kyiv, 04050, Ukraine
CI of Kyiv RC Regional Clinical Hospital #2
Kyiv, 04053, Ukraine
SI V.P.Komisarenko Institute of E&M of NAMSU
Kyiv, 04114, Ukraine
SI V.P.Komisarenko Institute of Endocrinology and Metabolism of NAMSU
Kyiv, 04114, Ukraine
Lviv Reg St Clin Treatment - Diagnostic Endocrin Center, Dept of Polyclinic, D.Galytskyy Lviv NMU
Lviv, 79010, Ukraine
Lviv Communal 4th City Clinical Hospital
Lviv, 79011, Ukraine
Center of Reconstructive & Restorative Medicine (University Clinic) of Odessa National Medical Uni
Odesa, 65000, Ukraine
CI Sumy City Clinical Hospital #1 Dept of Therapy Sumy SU Med Inst
Sumy, 40021, Ukraine
Ternopil City Municipal Hospital #2 Dept of Gastroenterology Ternopil I.Ya. Gorbachevskyi SMU
Ternopil, 46023, Ukraine
Transcarpathian Regional Clinical Cardiology Dispansery
Uzhhorod, 88014, Ukraine
Private Small Enterprise Medical Center Pulse
Vinnytsia, 21001, Ukraine
Vinnytsia RC Highly Special.Endocr.Center Dept of Therapy #2 M.I. Pyrogov NMU
Vinnytsia, 21010, Ukraine
National Pirogov Memorial Medical University
Vinnytsia, 21018, Ukraine
SRI of Invalid Rehabilitation (EST Complex) of Vinnytsia M.I.Pyrogov NMU MOHU
Vinnytsia, 21029, Ukraine
CI Zapor CCH#10 SI ZMA PGE Ch of therapy clin pharmacol & endocrin
Zaporizhzhia, 69001, Ukraine
CI Central City Hospital #1 of Zhytomyr
Zhytomyr, 10002, Ukraine
Zhytomyr regional clinical hospital n.a. O.F. Gerbachevskyy
Zhytomyr, 10002, Ukraine
Synexus Thames
Reading, Berkshire, RG2 0TG, United Kingdom
Mounts Bay Medical Ltd
Hayle, Cornwall, TR27 5DT, United Kingdom
Oak Tree Surgery
Liskeard, Cornwall, PL14 3XA, United Kingdom
The Alverton Practice
Penzance, Cornwall, TR18 4JH, United Kingdom
Rame Medical Limited
Torpoint, Cornwall, PL11 2TB, United Kingdom
Knowle House Surgery
Plymouth, Devon, PL5 3JB, United Kingdom
Torbay Hospital
Torquay, Devon, TQ2 7AA, United Kingdom
Synexus Clinical Research North Tees
Stockton-on-Tees, Durham, TS19 8PE, United Kingdom
Broomfield Hospital
Chelmsford, Essex, CM1 7ET, United Kingdom
Barts Hospital
London, Greater London, EC1A 7BE, United Kingdom
Manchester Royal Infirmary
Manchester, Greater Manchester, M13 9WL, United Kingdom
Synexus Manchester Clinical Research Centre
Manchester, Greater Manchester, M15 6SX, United Kingdom
Waterloo Medical Centre
Blackpool, Lancashire, FY4 3AD, United Kingdom
Synexus Lancashire Clinical Research Centre
Chorley, Lancashire, PR7 7NA, United Kingdom
Synexus Merseyside Clinical Research Centre
Liverpool, Merseyside, L22 0LG, United Kingdom
Synexus Hexham General Hospital
Hexham, Northumberland, NE46 1QJ, United Kingdom
Synexus Wales Clinical Research Centre
Cardiff, South Glamorgan, CF15 9SS, United Kingdom
Synexus Scotland Clinical Research Centre
Glasgow, Strathclyde, G20 OSP, United Kingdom
Ninewells Hospital
Dundee, Tayside Region, DD1 9SY, United Kingdom
Synexus Birmingham Clinical Research Centre
Birmingham, West Midlands, B15 2SQ, United Kingdom
Morriston Hospital
Swansea, SA6 6NL, United Kingdom
Related Publications (2)
Das Pradhan A, Glynn RJ, Fruchart JC, MacFadyen JG, Zaharris ES, Everett BM, Campbell SE, Oshima R, Amarenco P, Blom DJ, Brinton EA, Eckel RH, Elam MB, Felicio JS, Ginsberg HN, Goudev A, Ishibashi S, Joseph J, Kodama T, Koenig W, Leiter LA, Lorenzatti AJ, Mankovsky B, Marx N, Nordestgaard BG, Pall D, Ray KK, Santos RD, Soran H, Susekov A, Tendera M, Yokote K, Paynter NP, Buring JE, Libby P, Ridker PM; PROMINENT Investigators. Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk. N Engl J Med. 2022 Nov 24;387(21):1923-1934. doi: 10.1056/NEJMoa2210645. Epub 2022 Nov 5.
PMID: 36342113DERIVEDPradhan AD, Paynter NP, Everett BM, Glynn RJ, Amarenco P, Elam M, Ginsberg H, Hiatt WR, Ishibashi S, Koenig W, Nordestgaard BG, Fruchart JC, Libby P, Ridker PM. Rationale and design of the Pemafibrate to Reduce Cardiovascular Outcomes by Reducing Triglycerides in Patients with Diabetes (PROMINENT) study. Am Heart J. 2018 Dec;206:80-93. doi: 10.1016/j.ahj.2018.09.011. Epub 2018 Sep 29.
PMID: 30342298DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Results Point of Contact
- Title
- Director, Clinical Operations
- Organization
- Kowa Research Institute, Inc.
Study Officials
- STUDY DIRECTOR
Paul Ridker, MD
CCVDP & The Brigham and Women's Hospital
- STUDY DIRECTOR
Aruna Pradhan, MD
CCVDP & The Brigham and Women's Hospital
Publication Agreements
- PI is Sponsor Employee
- No
- Restrictive Agreement
- Yes
Study Design
- Study Type
- interventional
- Phase
- phase 3
- Allocation
- RANDOMIZED
- Masking
- QUADRUPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- INDUSTRY
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
February 23, 2017
First Posted
March 7, 2017
Study Start
March 23, 2017
Primary Completion
July 27, 2022
Study Completion
July 27, 2022
Last Updated
September 25, 2025
Results First Posted
September 25, 2025
Record last verified: 2025-09