Oxygenation of Paravertebral Muscles During Exercise in Chronic Low Back Pain Patients
OXYLOM
2 other identifiers
interventional
33
1 country
1
Brief Summary
The study evaluate paraspinal aerobic metabolism of chronic low back pain patients and healthy people during an original and standardized isokinetic protocol. The aim of this study is to determine a potential alteration of muscular aerobic metabolism in low back pain patients, in order to establish the underlying cause of pain and muscular fatigability characterizing low back pain patients. Then, the aim is to determine if functional rehabilitation program can improve it. the unit of care have access to metabolic adaptations in measuring the muscular oxygenation and the pulmonary oxygen consumption, using near infrared spectroscopy and gas analyser.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable low-back-pain
Started Jan 2017
Longer than P75 for not_applicable low-back-pain
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 11, 2017
CompletedFirst Submitted
Initial submission to the registry
February 7, 2017
CompletedFirst Posted
Study publicly available on registry
February 16, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 10, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
December 10, 2024
CompletedDecember 23, 2025
December 1, 2025
7.9 years
February 7, 2017
December 16, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Deoxyhemoglobin
Expressed in arbitrary unit, at rest and during the isokinetic exercises (2 exercises of 5 minutes)
20 minutes
Secondary Outcomes (6)
Oxygen consumption
20 minutes
Work rate
10 minutes
Rate of perceived exertion
10 minutes
Pain
10 minutes
Muscular blood volume
20 minutes
- +1 more secondary outcomes
Study Arms (2)
Low back pain patients
EXPERIMENTALSubjects included in physical rehabilitation program.
Control subjects
NO INTERVENTIONNo intervention administered
Interventions
Patients participate during 4 weeks to a physical rehabilitation program.
Eligibility Criteria
You may qualify if:
- For Low back pain patients: suffering from low back pain for at least 3 month
- For control subject: no back pain in the past year
You may not qualify if:
- Chronic cardiovascular, pulmonary, metabolic, neurologic disease
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Hôpital Swyngedhauw, CHRU
Lille, France
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
André Thevenon, MD, PhD
University Hospital, Lille
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Purpose
- BASIC SCIENCE
- Intervention Model
- FACTORIAL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
February 7, 2017
First Posted
February 16, 2017
Study Start
January 11, 2017
Primary Completion
December 10, 2024
Study Completion
December 10, 2024
Last Updated
December 23, 2025
Record last verified: 2025-12
Data Sharing
- IPD Sharing
- Will not share