NCT03054623|Terminated
Study Stopped
PI Left Institution
Hemodynamic Assessment of Distal Revascularization Interval Ligation
DRIL
Prospective Hemodynamic Assessment of Distal Revascularization Interval Ligation
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Sponsor study identifier
observational
4
1 country
2
Study Start
September 20, 2016
Actual (reported)Primary Completion
August 11, 2018
Actual (reported)Study Completion
August 11, 2018
Actual (reported)Our study seeks to define the effect of each component of the distal revascularization interval ligation (DRIL) procedure on the in vivo distal blood pressure of patients with ischemic steal, and to determine whether the interval ligation component of the DRIL procedure is necessary or not.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
August 11, 2018
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
September 20, 2016
Actual (reported)February 13, 2017
Actual (reported)February 15, 2017
Actual (reported)August 11, 2018
Actual (reported)August 11, 2018
Actual (reported)Difference in forearm pressures
one year
Proportion of interval ligation procedures
one year
Adult (\>18 yo) patients with chronic kidney disease with functioning antecubital-based arteriovenous fistulae and evidence of ischemic steal symptoms
The DRIL procedure involves creation of a bypass from an arterial inflow site (usually mid brachial artery) proximal to the fistula inflow, to the bifurcation of the brachial artery distal to the fistula, with ligation of the intervening native vessel, thus restoring distal flow while preserving flow through the fistula.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Adult (\>18 yo) patients with chronic kidney disease with functioning antecubital-based arteriovenous fistulae and evidence of ischemic steal symptoms
Tampa General Hospital
Tampa, Florida, 33606, United States
University of South Florida South Tampa Campus
Tampa, Florida, 33606, United States
Zanow J, Krueger U, Reddemann P, Scholz H. Experimental study of hemodynamics in procedures to treat access-related ischemia. J Vasc Surg. 2008 Dec;48(6):1559-65. doi: 10.1016/j.jvs.2008.06.040. Epub 2008 Sep 4.
Aimaq R, Katz SG. Using distal revascularization with interval ligation as the primary treatment of hand ischemia after dialysis access creation. J Vasc Surg. 2013 Apr;57(4):1073-8; discussion 1078. doi: 10.1016/j.jvs.2012.10.085. Epub 2013 Jan 29.
Karl Illig, MD
University of South Florida
4 participants (actual enrollment reported by the registry).
First Submitted
February 13, 2017
First Posted
February 15, 2017
Study Start
September 20, 2016
Actual (reported)Study to Compare Palindrome vs. BioFlo DuraMax Dialysis Catheters
Contact the study team to confirm eligibility.
Leake AE, Winger DG, Leers SA, Gupta N, Dillavou ED. Management and outcomes of dialysis access-associated steal syndrome. J Vasc Surg. 2015 Mar;61(3):754-60. doi: 10.1016/j.jvs.2014.10.038. Epub 2014 Dec 9.
Illig KA, Surowiec S, Shortell CK, Davies MG, Rhodes JM, Green RM. Hemodynamics of distal revascularization-interval ligation. Ann Vasc Surg. 2005 Mar;19(2):199-207. doi: 10.1007/s10016-004-0162-y.
Varble N, Day S, Phillips D, Mix D, Schwarz K, Illig KA, Chandra A. In vitro hemodynamic model of the arm arteriovenous circulation to study hemodynamics of native arteriovenous fistula and the distal revascularization and interval ligation procedure. J Vasc Surg. 2014 May;59(5):1410-7. doi: 10.1016/j.jvs.2013.04.055. Epub 2013 Jul 9.
Primary Completion
August 11, 2018
Actual (reported)Study Completion
August 11, 2018
Actual (reported)Last Updated
January 24, 2025
Record last verified: 2025-01
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
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