System Delay and Clinical Outcome Among Chinese Patients With AMI Treated With Reperfusion Therapy (MOODY Study)
MOODY
1 other identifier
observational
8,000
1 country
23
Brief Summary
Acute myocardial infarction (AMI) pose a pool clinical outcome to men and women whom treatment was delayed. However, reperfusion time was limited in previous studies. To evaluate the system delay and clinical outcomes among Chinese patients with AMI, consecutive inpatient case prospectively collected from 1999 to 2016. Basic data and innovative evidence will accelerate evidence-based clinical practice and policy making, and improve AMI patients outcomes finally.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 1999
Longer than P75 for all trials
23 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 1999
CompletedFirst Submitted
Initial submission to the registry
February 9, 2017
CompletedFirst Posted
Study publicly available on registry
February 13, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 30, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
September 30, 2017
CompletedDecember 6, 2017
December 1, 2017
18.5 years
February 9, 2017
December 5, 2017
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
30-Day Freedom From Mortality
All-cause death
30 days
Secondary Outcomes (4)
12-Month Freedom From Major Adverse Cardiac Events (MACE)
12 months
Cardiac death
12 months
Myocardial infarction
12 months
Target vessel revascularization
12 months
Study Arms (2)
Group 1
The patient received reperfusion therapy between 1999 January 1 and 2009 December 31
Group 2
The patient received reperfusion therapy between 2010 January 1 and 2016 December 31
Interventions
Eligibility Criteria
In China, hospitalized patients with acute myocardial infarction will be enrolled consecutively.
You may qualify if:
- Hospitalized patients with acute myocardial infarction according to positive cardiac biomarkers (Troponin I/T, CK-MB or CK≥ local laboratory upper limit of normal values within 24 hours after initial presentation, and at least one of the following two supporting evidence of ischemia (ischemic symptoms occurring within 24 hours before admission or up to 72 hours for STEMI; ECG changes indicative of new ischemia).
You may not qualify if:
- Previously enrolled in the similar study
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (23)
Changshu First People's Hospital
Changshu, Jiangsu, China
Changzhou Traditional Chinese Medicine Hospital
Changzhou, Jiangsu, China
Jintan People's Hospital
Jintan, Jiangsu, China
Liyang Hospital of TCM
Liyang, Jiangsu, China
Gaochun People's Hospital
Nanjing, Jiangsu, China
Anqing First People's Hospital
Anqing, China
The 123 Hospital of PLA
Bengbu, China
Changzhou Fouth People's Hospital
Changzhou, China
Huaian Second People's Hospital
Huai'an, China
Huainan Eastern Hospital
Huainan, China
Huainan Xinhua Hospital
Huainan, China
Maanshan Shiqiye Hospital
Ma’anshan, China
Muyang Traditional Chinese Medicine Hospital
Muyang, China
Nanjing First Hospital
Nanjing, China
Nanjing Pukou Central Hospital
Nanjing, China
Nnajing 81 Hospital
Nanjing, China
Nnajing Integrated Traditional Chinese and Westem Medicine Hospital
Nanjing, China
Taicang First People's Hospital
Taicang, China
Wuxi Third Hospital
Wuxi, China
Yixin People's Hospital
Wuxi, China
Yixing Traditional Chinese Medicine Hospital
Wuxi, China
Xuncheng Central Hospital
Xuancheng, China
Zhangjiagang First People's Hospital
Zhangjiagang, China
Related Publications (1)
Xue X, Kan J, Zhang JJ, Tian N, Ye F, Yang S, Qu H, Chen SL; MOODY trial investigators. Comparison in Prevalence, Predictors, and Clinical Outcome of VSR Versus FWR after Acute Myocardial Infarction: The Prospective, Multicenter Registry MOODY Trial-Heart Rupture Analysis. Cardiovasc Revasc Med. 2019 Dec;20(12):1158-1164. doi: 10.1016/j.carrev.2019.01.023. Epub 2019 Jan 23.
PMID: 30755362DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Shaoliang Chen, PhD
Nanjing First Hospital, Nanjing Medical University
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Vice President
Study Record Dates
First Submitted
February 9, 2017
First Posted
February 13, 2017
Study Start
January 1, 1999
Primary Completion
June 30, 2017
Study Completion
September 30, 2017
Last Updated
December 6, 2017
Record last verified: 2017-12
Data Sharing
- IPD Sharing
- Will not share