NCT03046524

Brief Summary

Objectives:

  1. 1.Identify the clinical characteristics of parathyroid (PTH) cancer and PTH atypical neoplasms
  2. 2.Investigate if PTH carcinoma and atypical neoplasm present a biological behaviour and have a different impact on the health of the patients

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Oct 2015

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 6, 2015

Completed
1.3 years until next milestone

First Submitted

Initial submission to the registry

February 2, 2017

Completed
6 days until next milestone

First Posted

Study publicly available on registry

February 8, 2017

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 16, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 16, 2017

Completed
Last Updated

February 7, 2018

Status Verified

February 1, 2018

Enrollment Period

2 years

First QC Date

February 2, 2017

Last Update Submit

February 6, 2018

Conditions

Keywords

Parathyroid CarcinomaParathyroid NeoplasmChart Review

Outcome Measures

Primary Outcomes (3)

  • Information Collected on Clinical Characteristics of Parathyroid (PTH) Cancer and PTH Atypical Neoplasms by Conducting a Retrospective Chart Review

    5 years

  • Information Collected on PTH Carcinoma's Biological Behaviour and Impact on the Health of the Patients by Conducting a Retrospective Chart Review

    5 years

  • Information Collected on Atypical Neoplasm's Biological Behaviour and Impact on the Health of the Patients \by Conducting a Retrospective Chart Review

    5 years

Study Arms (2)

Parathyroid Carcinoma

Charts from participants with histopathological diagnosis of parathyroid carcinoma.

Other: Chart Review

Atypical Parathyroid Neoplasm

Charts from participants with parathyroid tumors with some atypical features found in parathyroid carcinoma, but not enough histologic criteria to make the diagnosis of parathyroid carcinoma.

Other: Chart Review

Interventions

Data between the years of 1/1/2002 and 12/31/2013 analyzed.

Atypical Parathyroid NeoplasmParathyroid Carcinoma

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The medical records of all adult patients that had a parathyroidectomy for primary PHPT in MD Anderson Cancer Center between the years of 1/1/2002 and 12/31/2013.

You may qualify if:

  • All patients from MDACC diagnosed with PHPT that have a histopathological diagnosis of PTH carcinoma or atypical parathyroid neoplasm between the years 1/1/2002 and 12/31/2013

You may not qualify if:

  • Pediatric patients
  • Cases with incomplete records
  • Patients where the follow-up will be less than six months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Texas MD Anderson Cancer Center

Houston, Texas, 77030, United States

Location

Related Links

MeSH Terms

Conditions

Parathyroid Neoplasms

Condition Hierarchy (Ancestors)

Endocrine Gland NeoplasmsNeoplasms by SiteNeoplasmsHead and Neck NeoplasmsEndocrine System DiseasesParathyroid Diseases

Study Officials

  • Nancy D. Perrier, MD

    M.D. Anderson Cancer Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 2, 2017

First Posted

February 8, 2017

Study Start

October 6, 2015

Primary Completion

October 16, 2017

Study Completion

October 16, 2017

Last Updated

February 7, 2018

Record last verified: 2018-02

Locations