Outcome of Colonoscopy Screening and Surveillance

NCT01827241 | Unknown

• 1 other identifier: DR11-0264
• Study Type: observational
• Target: 5,000
• Locations: 1 country
• Sites: 1

Brief Summary

With this study, we plan to review the performance of colonoscopy in colon cancer screening and surveillance, especially with the recent improvements in endoscopic technology (high definition endoscopes), use of split dose preparation which provides excellent colon preparation for detection of lesions and increasing awareness and detection of flat lesions of the colon. The findings will help us define the role of colonoscopy screening of colon polyps and flat lesions and identity areas for improvement. The data will be used for continuing quality improvement and presenting our outcomes at academic meetings and publishing our results in peer reviewed journals.

Conditions

Gastroenterology

Keywords

Gastroenterology; Colonoscopy; Screening; Surveillance; Symptom evaluation; Chart review; Data review; Examination findings; Resection techniques; Pathology reports

Outcome Measures

Primary Outcomes (1)

• Polyp Detection in Colon Cancer Screening and Surveillance

  Descriptive tables presented for demographics, polyp counts, colonoscopy experiences, polyp removals and findings. Proportions presented with 95% confidence intervals. Continuous values such as age and times presented with median, minimum and maximum. Comparisons among patient subgroups made with chi-square tests for categorical data and t-tests or the non-parametric alternative, Wilcoxon tests, to compare continuous measures. Graphics such as box plots, trellis plots, bar graphs, or stacked bar graphs used to describe distributions overall and among subgroups.

  9 years

Study Arms (1)

Colonoscopy Outcomes

Data collected from endoscopy reports to complete a descriptive analysis of demographics, colonoscopy procedure performance, and assess type of benign colon polyps detected during screening and surveillance from 02/01/2009 - 12/31/2020.

Other: Chart Review

Interventions

Chart Review OTHER

Retrospective and prospective data review of colonoscopy procedures, examination findings, resection techniques, and pathology reports.

Colonoscopy Outcomes

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Chart review from participants receiving colonoscopy at UT MD Anderson Cancer Center in Houston, Texas from 02/01/2009 - 12/31/2020.

You may qualify if:

• \. All Patients who have undergone colonoscopy for screening, surveillance or symptom evaluation.

You may not qualify if:

• \. None

Sponsors & Collaborators

• M.D. Anderson Cancer Center: lead

Study Sites (1)

University of Texas MD Anderson Cancer Center

Houston, Texas, 77030, United States

RECRUITING

Related Publications (1)

• Raju GS, Lum PJ, Ross WA, Thirumurthi S, Miller E, Lynch PM, Lee JH, Bhutani MS, Shafi MA, Weston BR, Pande M, Bresalier RS, Rashid A, Mishra L, Davila ML, Stroehlein JR. Outcome of EMR as an alternative to surgery in patients with complex colon polyps. Gastrointest Endosc. 2016 Aug;84(2):315-25. doi: 10.1016/j.gie.2016.01.067. Epub 2016 Feb 6.

  PMID: 26859866 DERIVED

Related Links

• University of Texas MD Anderson Cancer Center Website

Study Officials

• Gottumukkala S. Raju, MD

  M.D. Anderson Cancer Center

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Gottumukkala S. Raju, MD

CONTACT

713-792-5496; GSRaju@mdanderson.org

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 2, 2013
• First Posted: April 9, 2013
• Study Start: September 1, 2011
• Primary Completion: December 1, 2021
• Study Completion: December 1, 2022
• Last Updated: May 15, 2019

Record last verified: 2019-05

Locations

US (1)