Posterior Maxillary Ridge Augmentation With Sinus Lift Using Mineralized Plasmatic Matrix Versus Autogenous Bone Graft

NCT03014388 | Unknown

• 1 other identifier: CairoU MPM
• Study Type: interventional
• Target: 20
• Locations: 0 countries
• Sites: N/A

Brief Summary

Using growth factors obtained from patient's venous blood mixed with particulate autogenous bone the study compares bone gain by implant with gold standards in sinus Lift procedures for future implant insertion.

Conditions

Bone Resorption

Outcome Measures

Primary Outcomes (1)

• Patient Satisfaction regarding aesthetic results will be measured using questionnaire.

  outcome will be measure using questionnaire.

  9 months

Secondary Outcomes (1)

• Stability of dental implants.

  5 months

Study Arms (2)

Autogenous bone graft (Gold Standard).

EXPERIMENTAL

Patients with defective posterior maxillary alveolar ridges requiring implant insertion will have Autogenous bone graft (Gold standard) and to be used for bone augmentation with sinus lift.

Other: autogenous bone

Mineralized Plasmatic Matrix (MPM)

EXPERIMENTAL

Patients with defective posterior maxillary alveolar ridges requiring implant insertion will receive bone graft using Mineralized plasmatic matrix.

Other: Mineralized plasmatic matrix

Interventions

autogenous bone OTHER

Autogenous bone graft (gold standard). sinus lift with autogenous bone.

Also known as: Autobone

Autogenous bone graft (Gold Standard).

Mineralized plasmatic matrix OTHER

By using venoud blood from the patient, together with bone graft, a centrifuge will be used to obtain the top layer after centrifuging blood at 3000 RPM.

Also known as: MPM

Mineralized Plasmatic Matrix (MPM)

Eligibility Criteria

• Age: 18 Years - 50 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Patients systemically free.
• Patients with posterior maxillary defective ridges indicated for sinus lift procedure.
• Cases with 5 mm bone height or less are included in the study.
• Age between 18 and 50 years.
• Both sexes.
• Patients physically able to tolerate surgical and restorative procedures.
• Good oral hygiene.
• Highly motivated patients.

You may not qualify if:

• Patients allergic to local anesthetic agent.
• Medium and heavy smokers.
• Pregnant females.
• Presence of any pathosis in the pre-implant site.
• Presence of any mucosal disease.
• History of oral radiotherapy.
• History of prolonged steroids use.
• Psychological disorders.

Sponsors & Collaborators

• Cairo University: lead

MeSH Terms

Conditions

Bone Resorption

Condition Hierarchy (Ancestors)

Bone Diseases; Musculoskeletal Diseases

Study Officials

• Cairo University CBE

  Cairo University - Ethics Committee.

  PRINCIPAL INVESTIGATOR

Central Study Contacts

refaat ragab, Master

CONTACT

01111175536; refaat.ragab.rr@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dentist at menistry of health

Study Record Dates

• First Submitted: January 5, 2017
• First Posted: January 9, 2017
• Study Start: January 1, 2017
• Primary Completion: September 1, 2017
• Study Completion: October 1, 2017
• Last Updated: January 9, 2017

Record last verified: 2016-12

Data Sharing

• IPD Sharing: Will not share