NCT03013478

Brief Summary

To conduct an 8-week randomized trial evaluating the feasibility and efficacy of adding CBT4CBT to treatment as usual in a community based primary care program in a population of 60 individuals who meet current DSM criteria for substance use disorder other than nicotine.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
58

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Nov 2016

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2016

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

January 4, 2017

Completed
2 days until next milestone

First Posted

Study publicly available on registry

January 6, 2017

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 31, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 31, 2018

Completed
Last Updated

September 12, 2018

Status Verified

September 1, 2018

Enrollment Period

1.8 years

First QC Date

January 4, 2017

Last Update Submit

September 11, 2018

Conditions

Outcome Measures

Primary Outcomes (2)

  • retention in treatment

    subjects returning for treatment at primary care unit and completing CBT4CBT program for those assigned

    0 - 8 weeks

  • reduction in drug use

    Using urine and breathalyzer screening for negative drug and alcohol testing

    0 - 8 weeks

Study Arms (2)

Standard treatment as usual (TAU)

NO INTERVENTION

Treatment normally offered at this primary care clinic

TAU plus CBT4CBT program

ACTIVE COMPARATOR

Treatment normally offered at this clinic PLUS 8 weeks of CBT4CBT computerized therapy.

Behavioral: Standard Treatment As Usual (TAU)Behavioral: CBT4CBT program

Interventions

Treatment normally offered at this primary care clinic

TAU plus CBT4CBT program
CBT4CBT programBEHAVIORAL
TAU plus CBT4CBT program

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Are 18 years of age or older.
  • Are applying for outpatient substance abuse treatment
  • Meet current DSM-IV criteria for cocaine, marijuana, opioid, alcohol or other stimulant use disorder
  • Are sufficiently stable for 8 weeks of outpatient treatment
  • Can commit to 8 weeks of treatment and are willing to be randomized to treatment
  • Are willing to provide locator information.

You may not qualify if:

  • Have an untreated bipolar or schizophrenic disorder
  • Have a current legal case pending such that incarceration during the 8 week protocol is likely
  • Are in need of detoxification from alcohol, opioids or benzodiazepines

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Yale New Haven Hospital St Raphael's Campus

New Haven, Connecticut, 06604, United States

Location

Related Publications (1)

  • Tetrault JM, Holt SR, Cavallo DA, O'Connor PG, Gordon MA, Corvino JK, Nich C, Carroll KM. Computerized Cognitive Behavioral Therapy for Substance Use Disorders in a Specialized Primary Care Practice: A Randomized Feasibility Trial to Address the RT Component of SBIRT. J Addict Med. 2020 Dec;14(6):e303-e309. doi: 10.1097/ADM.0000000000000663.

MeSH Terms

Conditions

Substance-Related Disorders

Condition Hierarchy (Ancestors)

Chemically-Induced DisordersMental Disorders

Study Officials

  • Kathleen M Carroll, PhD

    Yale University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 4, 2017

First Posted

January 6, 2017

Study Start

November 1, 2016

Primary Completion

August 31, 2018

Study Completion

August 31, 2018

Last Updated

September 12, 2018

Record last verified: 2018-09

Data Sharing

IPD Sharing
Will share

Locations