NCT03009448

Brief Summary

Analysis of recent studies show that researchers find it hard to distinguish between Late Onset Depression, a first diagnosed major depressive episode which occurs at old age, and Early Onset Depression, a depressive episode at old age with a history of previous episodes. Since current data, about the phenomenology and etiology of Late Onset Depression, lake conicity it is unclear whether this phenomena should be considered as a distinct subtype of depression. Nevertheless, the wide spread assumption is that Late Onset Depression has a stronger correlation with brain damage and environmental risk factors such as the common losses at old age and weaker correlation with family history and genetics when compared to Early Onset. Although many researchers consider brain damage to have the main contribution to the emerge of Late Onset Depression, the fact that depression has a negative effect on one's health supports the claim that it might be the result and not the rick factor. Since Late Onset Depression correlates with the common losses at old age, the investigators propose that an existential approach that deals with one's meaning, freedom, responsibly and death, might be more appropriate. Thus, the investigators ask how do older adults experience depression which they face for the first time in old age? Current study will seek to understand older adults' experience of Late Onset depression through existential paradigm by using a semi constructed interview.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
15

participants targeted

Target at below P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 23, 2016

Completed
12 days until next milestone

First Posted

Study publicly available on registry

January 4, 2017

Completed
2 months until next milestone

Study Start

First participant enrolled

March 1, 2017

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2017

Completed
Last Updated

January 4, 2017

Status Verified

December 1, 2016

Enrollment Period

7 months

First QC Date

December 23, 2016

Last Update Submit

December 31, 2016

Conditions

Outcome Measures

Primary Outcomes (1)

  • Data analysis

    All the data collected, from each semi structured interview, will be analyzed by the investigator to find similarities or differences between the older adults' experience and to identify specific existential themes.

    10 weeks

Study Arms (1)

Late onset depression

Other: Interview

Interventions

Each subject will be interviewed using a semi constructed interview.

Late onset depression

Eligibility Criteria

Age62 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Israeli men and women after the age of retirement, 67 and 62 respectably, who are diagnosed with a major depressive episode, minor depressive episode or show depressive symptoms for the first time in their lives at old age.

You may qualify if:

  • Men aged 67 or more, women aged 62 or more
  • Diagnosis of Major Depressive Disorder, Minor Depressive Disorder or Adjustment Disorder with depressive features made after the age of 67 with men and 62 with women.
  • Basic understanding and ability to converse in Hebrew.

You may not qualify if:

  • History of at least one previous major depressive or minor depressive episode before the age of 62 with women or 67 with men
  • Mental Retardation or Autistic Spectrum Disorder
  • Significant cognitive impairment observed by the primary physician.
  • Schizophrenia or Schizoaffective disorder.
  • Depressive episode with psychotic features
  • Substantial suicidality

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Shalvata MHC

Hod HaSharon, Israel

Location

MeSH Terms

Conditions

Depressive Disorder, Major

Interventions

Interviews as Topic

Condition Hierarchy (Ancestors)

Depressive DisorderMood DisordersMental Disorders

Intervention Hierarchy (Ancestors)

Data CollectionEpidemiologic MethodsInvestigative TechniquesHealth Care Evaluation MechanismsQuality of Health CareHealth Care Quality, Access, and EvaluationPublic HealthEnvironment and Public Health

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 23, 2016

First Posted

January 4, 2017

Study Start

March 1, 2017

Primary Completion

October 1, 2017

Last Updated

January 4, 2017

Record last verified: 2016-12

Locations