NCT02966639

Brief Summary

The main objective of this study is the external validation of the appropriateness criteria for the surgical treatment of Lumbar Degenerative Spondylolisthesis. We will assess, prospectively, whether patients treated "appropriately" have better outcomes than those treated "inappropriately" according to the RAND Appropriateness Method (RAM) Criteria.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
171

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Oct 2016

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2016

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

November 14, 2016

Completed
3 days until next milestone

First Posted

Study publicly available on registry

November 17, 2016

Completed
4.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2021

Completed
Last Updated

August 9, 2021

Status Verified

August 1, 2021

Enrollment Period

4.7 years

First QC Date

November 14, 2016

Last Update Submit

August 5, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Core Outcome Measures Index

    12-months Post-Treatment

Secondary Outcomes (5)

  • Oswestry Disability Index

    12-months Post-Treatment

  • Global Outcome of Treatment Questions

    12-months Post-Treatment

  • Satisfaction with Care

    12-months Post-Treatment

  • Complications from Treatment

    12-months Post-Treatment

  • Further Treatment after Initial Treatment

    12-months Post-Treatment

Study Arms (1)

LDS Patients

All patients with a diagnosis of single-level Lumbar Degenerative Spondylolisthesis who present to the DHMC Spine Center.

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Skeletally mature individuals with a primary pathology of single-level degenerative spondylolisthesis in the lumbar region of the spine.

You may qualify if:

  • Is the patient skeletally mature with a primary pathology of single level degenerative spondylolisthesis in the lumbar region of the spine (with or without stenosis at other levels)?
  • Able to give written informed consent
  • Patient has already undertaken a course of non-operative care

You may not qualify if:

  • Primarily degenerative scoliosis curvature greater than 15 degrees
  • Presence of Isthmic Spondylolisthesis
  • Cauda equine syndrome requiring immediate emergency surgery
  • Active spinal infection, tumor, or unhealed fracture
  • Inability to understand English
  • Patient refused to participate.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Dartmouth-Hitchcock Medical Center

Lebanon, New Hampshire, 03756, United States

Location

MeSH Terms

Conditions

Spondylolisthesis

Condition Hierarchy (Ancestors)

SpondylolysisSpondylosisSpinal DiseasesBone DiseasesMusculoskeletal Diseases

Study Officials

  • Adam M Pearson, MD

    Dartmouth-Hitchcock Medical Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Staff Physician

Study Record Dates

First Submitted

November 14, 2016

First Posted

November 17, 2016

Study Start

October 1, 2016

Primary Completion

June 1, 2021

Study Completion

June 1, 2021

Last Updated

August 9, 2021

Record last verified: 2021-08

Data Sharing

IPD Sharing
Will share

Locations