NCT07547969

Brief Summary

this study will be conducted to investigate the effect of hip extension mobilization on lumber disability, pain and flexion range of motion in patients with spondylolisthesis

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
32

participants targeted

Target at P25-P50 for not_applicable

Timeline
1mo left

Started Apr 2026

Shorter than P25 for not_applicable

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress35%
Apr 2026Jun 2026

First Submitted

Initial submission to the registry

April 17, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

April 23, 2026

Completed
2 days until next milestone

Study Start

First participant enrolled

April 25, 2026

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2026

Last Updated

April 23, 2026

Status Verified

April 1, 2026

Enrollment Period

1 month

First QC Date

April 17, 2026

Last Update Submit

April 17, 2026

Conditions

Keywords

hip extension mobilizationSpondylolisthesisfunctional disability

Outcome Measures

Primary Outcomes (1)

  • low back disability

    Arabic version of Roland Morris Disability will be used to assess low back disability. it is a valid, reliable 24-item tool used to assess physical disability in patients with low back pain (LBP). It has been culturally adapted to Modern Standard Arabic, with a score ranging from 0 to 24, where higher scores indicate greater functional disability.

    up to four weeks

Secondary Outcomes (2)

  • pain intensity

    up to four weeks

  • lumbar flexion range of motion

    up to four weeks

Study Arms (2)

hip extension mobilization

EXPERIMENTAL

Sixteen patients received hip extension mobilization with conventional treatment (William spinal flexion exercises and TENS) three times per week for one month.

Other: hip extension mobilizationOther: conventional treatment

conventional treatment

ACTIVE COMPARATOR

Sixteen patients received conventional treatment in the form of William's spinal flexion exercises and TENS three times per week for one month.

Other: conventional treatment

Interventions

the patients will receive hip extension mobilization to increase hip extension range of motion; the therapist applies an anterior glide mobilization-usually with the patient in a prone position. The patient is positioned in prone at the edge of the table. The hip is then flexed, abducted, and externally rotated into position as tolerated by the patient, and the foot is placed next to the contralateral knee. Impart anterior mobilization through the greater trochanter. The therapist applies a grade IV mobilization in a posterior to anterior direction to target the anterior hip. The mobilizing hand applies a downward ward force through an extended elbow; body weight exerts the force+ cinentional treatment

hip extension mobilization

Each subject will be given treatment of 30-40 minute session of William flexion exercises. The seven variations of Williams's exercises include (Pelvic tilt, single knee to chest, double knee to chest, half sit-up, hamstring stretch, hip flexor stretches, and squat). in additionn, The TENS electrodes are typically placed bilaterally along the lumbar paraspinal region directly over the painful area. The frequency of the output was set at 4 to 8 Hz. Continuous type used.

conventional treatmenthip extension mobilization

Eligibility Criteria

Age40 Years - 60 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Chronic female Patients diagnosed as grade 1 lumbar degenerative spondylolisthesis (anterolisthesis) referred from Orthopedists was confirmed by lumbosacral x-ray
  • Patients age ranged from 40 to 60 years.
  • BMI(25:35)
  • Ambulant patient with or without cane.
  • Cooperative patients with ability to understand instructions and follow simple verbal commands.

You may not qualify if:

  • Osteoporosis.
  • Pregnancy.
  • Signs consistent with nerve root compression (reproduction of low-back or leg pain with a straight leg raise at less than 45°, muscle weakness involving a major muscle group of the lower extremity, diminished lower extremity muscle stretch reflex, or diminished or absent sensation to pinprick in any lower extremity dermatome).
  • General tumors, spinal tumor, fracture, cauda equina syndrome, and previous surgery.
  • Other causes of spondylolisthesis.
  • Patients with (BMI ≥ 35)
  • Severe or life-threatening psychiatric illness.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Spondylolisthesis

Condition Hierarchy (Ancestors)

SpondylolysisSpondylosisSpinal DiseasesBone DiseasesMusculoskeletal Diseases

Central Study Contacts

Alaa Kazamel, master

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
opaque sealed envelope
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: mobilization and conventional treatment
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
principle investigator : Alaa Ahmed Kazamel

Study Record Dates

First Submitted

April 17, 2026

First Posted

April 23, 2026

Study Start

April 25, 2026

Primary Completion (Estimated)

June 1, 2026

Study Completion (Estimated)

June 1, 2026

Last Updated

April 23, 2026

Record last verified: 2026-04