Functional Neuroimaging and Genetic Vulnerability to Suicidal Behavior

NCT02960191 | Terminated

• 1 other identifier: 7887
• Study Type: interventional
• Target: 95
• Locations: 1 country
• Sites: 1

Brief Summary

The main objective is to highlight, by functional imaging (MRI) dysfunctional brain regions associated with vulnerability to suicidal behavior.

Conditions

Suicidal Behavior

Outcome Measures

Primary Outcomes (1)

• MRI variations

  activation of specific brain areas during the procurement of a test decision

  at day 0

Study Arms (3)

healthy volunteers

OTHER

subject with no current or past personal history of psychiatric disorders and about never having carried out suicide attempt

Device: Magnetic resonance imaging (MRI)

emotional witness

OTHER

subject having had a personal history of unipolar or bipolar depressive disorder and who have never done in his life attempted suicide

Device: Magnetic resonance imaging (MRI)

patient suicide

OTHER

subject having had a personal history of unipolar or bipolar depressive disorder and having realized in his life at least one suicide attempt

Device: Magnetic resonance imaging (MRI)

Interventions

Magnetic resonance imaging (MRI) DEVICE

emotional witness; healthy volunteers; patient suicide

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• right-handed
• arm suicidal : Personal history of unipolar depressive disorder or bipolar disorder and having realized in his life at least one suicide attempt
• arm emotional Witnesses : Personal history of unipolar depressive disorder or bipolar disorder and have never done in his life attempted suicide
• arm healthy Witnesses : any current or past personal history of psychiatric disorders of Axis I and have never done in his life attempted suicide

You may not qualify if:

• Cons-indications to the use of MRI
• Existence of a past history of head trauma with loss of consciousness or neurological brain disorder or secondary neurological suffering suicidal gesture.

Sponsors & Collaborators

• University Hospital, Montpellier: lead

Study Sites (1)

University Hospital of Montpellier

Montpellier, 34295, France

Location

MeSH Terms

Interventions

Magnetic Resonance Imaging

Intervention Hierarchy (Ancestors)

Tomography; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 30, 2016
• First Posted: November 9, 2016
• Study Start: December 1, 2008
• Primary Completion: March 1, 2012
• Study Completion: March 1, 2012
• Last Updated: November 9, 2016

Record last verified: 2016-11

Locations

FR (1)