NCT02946281

Brief Summary

The primary objective of Do CHANGE is to develop a health ecosystem for integrated disease management of citizens with high blood pressure and patients with ischemic heart disease or heart failure. The system will give them access to a set of personalized health services in a near real-time fashion. This disruptive system will incorporate the behaviour change methods, such as "Do Something Different", in conjunction with new innovative wearable/portable tools that can monitor behaviour and clinical parameters in normal living situations.

Trial Health

90
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
149

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Dec 2016

Geographic Reach
2 countries

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 7, 2016

Completed
4 months until next milestone

First Posted

Study publicly available on registry

October 27, 2016

Completed
2 months until next milestone

Study Start

First participant enrolled

December 19, 2016

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 22, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 22, 2017

Completed
Last Updated

July 26, 2018

Status Verified

July 1, 2018

Enrollment Period

1 year

First QC Date

July 7, 2016

Last Update Submit

July 25, 2018

Conditions

Keywords

self-managementhealth behaviorcardiac diseasehabitslifestyle

Outcome Measures

Primary Outcomes (3)

  • Lifestyle

    The Health Promoting Lifestyle Questionnaire (HPLP-II) will be administered to evaluate whether patients' subjective perception of lifestyle change has changed.

    0-6 months

  • Behavioural flexibility

    Whether the patients' behavioural flexibility (having a bigger behavioural repertoire which makes it easier to perform alternative behaviours) has increased and thus whether behaviour change (as conceptualized by Do Something Different program) has occurred will be assessed using purpose designed questions by the Do Something Different program.

    6 months

  • Quality of life

    Changes in quality of life will be assessed using the WHOQOL-Bref questionnaire. As this is a widely used instrument it will allow the integration of data from different partners.

    6 months

Secondary Outcomes (2)

  • Usability, acceptance, satisfaction with intervention / tools

    3 months

  • Cost-effectiveness

    6 months

Other Outcomes (3)

  • Depression

    6 months

  • Anxiety

    6 months

  • Lifestyle data sensor generated

    3 months

Study Arms (2)

Intervention

EXPERIMENTAL
Behavioral: Do CHANGE

Care as usual

NO INTERVENTION

Interventions

Do CHANGEBEHAVIORAL

The intervention aims to increase behavioral flexibility and change patients' (unhealthy) lifestyle. At the same time the intervention should increase patient self-management and improve the patient reported outcomes (e.g. quality of life, anxiety, depression).

Also known as: Do Something Different, Docobo Care Portal, Moves app, Blood pressure monitor UA -767 Plus
Intervention

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • age 18-75 years
  • diagnosed with CAD, HF or HT
  • having at least two of the following risk factors: smoking, positive family history, increased cholesterol, diabetes, sedentary lifestyle, psychosocial risk factors.
  • Patients should also have access to the Internet and have a smartphone (and sufficient knowledge on using personal computer or smartphone)
  • Patients should have sufficient knowledge of the countries' native language.

You may not qualify if:

  • significant cognitive impairments (e.g. dementia)
  • patients who are on the waiting list for heart transplantation
  • life expectancy \<1 year
  • life threatening comorbidities (e.g. cancers)
  • history of psychiatric illness other than anxiety/depression
  • patients who do not have access to internet
  • patients with insufficient knowledge of the local pilot language (Dutch, Chinese and Catalonian).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Elisabeth-TweeSteden Hospital

Tilburg, North Brabant, Netherlands

Location

Badalona Serveis Assistencials

Badalona, Spain

Location

Related Publications (2)

  • Habibovic M, Piera-Jimenez J, Wetzels M, Widdershoven JWGM, Soedamah-Muthu SS. Associations between behavioral flexibility and health behavior in cardiac patients in the Do CHANGE trials. Health Psychol. 2022 Oct;41(10):710-718. doi: 10.1037/hea0001151. Epub 2022 May 16.

  • Broers ER, Kop WJ, Denollet J, Widdershoven J, Wetzels M, Ayoola I, Piera-Jimenez J, Habibovic M. A Personalized eHealth Intervention for Lifestyle Changes in Patients With Cardiovascular Disease: Randomized Controlled Trial. J Med Internet Res. 2020 May 22;22(5):e14570. doi: 10.2196/14570.

MeSH Terms

Conditions

Health BehaviorHeart DiseasesHabits

Condition Hierarchy (Ancestors)

BehaviorCardiovascular Diseases

Study Officials

  • Jos Widdershoven, Prof. dr.

    Elisabeth-TweeSteden Ziekenhuis

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Prof. Dr.

Study Record Dates

First Submitted

July 7, 2016

First Posted

October 27, 2016

Study Start

December 19, 2016

Primary Completion

December 22, 2017

Study Completion

December 22, 2017

Last Updated

July 26, 2018

Record last verified: 2018-07

Locations