NCT02271529

Brief Summary

The objective of this study is to evaluate the performance of the Zilver PTX stent thumbwheel delivery system.

Trial Health

90
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Sep 2014

Shorter than P25 for not_applicable

Geographic Reach
3 countries

6 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2014

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

October 17, 2014

Completed
5 days until next milestone

First Posted

Study publicly available on registry

October 22, 2014

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2015

Completed
10 months until next milestone

Results Posted

Study results publicly available

February 26, 2016

Completed
Last Updated

February 26, 2016

Status Verified

January 1, 2016

Enrollment Period

8 months

First QC Date

October 17, 2014

Results QC Date

January 29, 2016

Last Update Submit

January 29, 2016

Conditions

Keywords

Peripheral Vascular DiseaseFemoral ArteryDrug-Eluting Stent

Outcome Measures

Primary Outcomes (1)

  • Mean Percent Change in Stent Length Upon Deployment

    Immediately following completion of the stent placement procedure

Study Arms (1)

Drug Eluting Stent

EXPERIMENTAL

Zilver® Paclitaxel(PTX)® Drug-Eluting Peripheral Stent

Device: Zilver® PTX® Drug-Eluting Peripheral Stent

Interventions

Treatment of symptomatic vascular disease of the native above-the-knee femoropopliteal arteries.

Drug Eluting Stent

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patient has symptomatic vascular disease of the native above-the-knee femoropopliteal arteries
  • Patient has atherosclerotic lesion of the above-the-knee femoropopliteal artery

You may not qualify if:

  • Patient is \< 18 years of age
  • Patient unable to complete required follow-up assessments
  • Patient unwilling to sign and date the informed consent
  • Simultaneous participation in another investigational drug or device study
  • Pregnant, breastfeeding or planning to become pregnant in the next 5 years
  • Additional medical/anatomical restrictions as specified in the Clinical Investigation Plan

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (6)

Frankston Hospital

Frankston, Vic 3199, Australia

Location

Princess Alexandra Hospital

Woolloongabba, Qld 4102, Australia

Location

Universitäts-Herzzentrum Freiburg - Bad Krozingen GmbH

Bad Krozingen, D-79189, Germany

Location

Auckland City Hospital

Auckland, 1023, New Zealand

Location

Waikato Hospital

Hamilton, 3248, New Zealand

Location

Wellington Hospital

Wellington, 3248, New Zealand

Location

MeSH Terms

Conditions

Peripheral Vascular Diseases

Condition Hierarchy (Ancestors)

Vascular DiseasesCardiovascular Diseases

Results Point of Contact

Title
Scott Snyder, Director, Clinical Affairs
Organization
Cook Research Incorporated

Study Officials

  • Andrew Holden, MD

    Auckland District Health Board

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
GT60
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 17, 2014

First Posted

October 22, 2014

Study Start

September 1, 2014

Primary Completion

May 1, 2015

Study Completion

May 1, 2015

Last Updated

February 26, 2016

Results First Posted

February 26, 2016

Record last verified: 2016-01

Locations