Application of Mechanical Cardiopulmonary Resuscitation Devices and Their Value in Out-of-hospital Cardiac Arrest: A Retrospective Analysis of the German Resuscitation Registry

NCT02932124 | Completed

• 1 other identifier: GRR-CC07-14
• Study Type: observational
• Target: 19,609
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim of this study was to analyse a large CPR database, the German Resuscitation Registry, to evaluate potential benefits of mechanical CPR devices over manual CPR in adult cardiac arrest victims. The primary endpoint considered is ROSC.

Conditions

Out-of-hospital Cardiac Arrest

Keywords

German Resuscitation Registry; out-of-hospital cardiac arrest; cardiopulmonary resuscitation; mechanical chest compression devices

Outcome Measures

Primary Outcomes (1)

• return of spontaneous circulation

  sustained return of spontaneous circulation at any time during CPR

  sustained ROSC at any time latest after 24 hours

Study Arms (2)

1

manual chest compressions

2

mechanical chest compression

Device: mechanical chest compression device

Interventions

mechanical chest compression device DEVICE

2

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patient suffering OHCA and be resuscitated by EMS where the data were delivered to the German Resuscitation Registry

You may qualify if:

• out of hospital cardiac arrest
• during time prod from January 2007 until December 2014
• CPR attempted

You may not qualify if:

• Investigators excluded cases in which CPR was continued for less than five minutes, or duration of CPR was missing, as the outcome in this early period is not affected by the CPR mode.
• Children aged less than 18 years and patients of unknown age were also excluded as the devices are not approved for resuscitation on children.
• An active compression-decompression (ACD) is a hand-held suction device, to compress and actively decompress the chest after each compression.
• Investigators also excluded cases where ACD CPR was used, because it constitutes a different technology.
• Cases due to trauma were excluded as application of mechanical CPR devices may be limited due in traumatic events.
• Cases where data on ROSC and/or CPR mode was missing were also excluded.

Sponsors & Collaborators

• German Resuscitation Registry: lead

MeSH Terms

Conditions

Out-of-Hospital Cardiac Arrest

Condition Hierarchy (Ancestors)

Heart Arrest; Heart Diseases; Cardiovascular Diseases

Study Officials

• Jan Wnent, MD

  German Resuscitation Registry

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PD Dr.

Study Record Dates

• First Submitted: October 6, 2016
• First Posted: October 13, 2016
• Study Start: January 1, 2007
• Primary Completion: December 1, 2014
• Study Completion: December 1, 2014
• Last Updated: October 13, 2016

Record last verified: 2016-10

Data Sharing

• IPD Sharing: Will not share