The Effect of Exercise on Physical Function and Health in Older People After Discharge From Hospital

NCT02905383 | Completed

• 1 other identifier: 2015/2432
• Study Type: interventional
• Target: 88
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to investigate the effect of a multi-component exercise program on physical function, physical activity and health-related quality of life (HRQOL) in older people recently discharged from hospital. The intervention consists of 32 group-based exercise sessions, performed twice a week. In addition the participants in the intervention group will be encouraged to perform an exercise program on their own, at least once weekly. The participants in the control group will be encouraged to exercise on their own, according to the World Health Organization (WHO) recommendations on physical activity for adults aged 65 and above.

Conditions

Chest Pain; Pneumonia; Transient Ischemic Attack; Stroke; Functional Failure

Outcome Measures

Primary Outcomes (1)

• Changes in physical function

  Changes in physical function will be measured with The Short Physical Performance Battery (SPPB). This test evaluates balance, mobility and muscle strength by examining an individual's ability to stand with feet together side-by side, semitandem and tandem positions, time to walk 8ft and time to rise from a chair and return to the seated position five times. Each of the three tests is scored, based on performance between 0 and 4, leaving a maximum score of 12 for those individuals performing at the highest levels.

  Baseline, 4 months and 8 months

Secondary Outcomes (9)

• Berg Balance Scale

  Baseline, 4 months and 8 months

• Health-related quality of life (HRQOL)

  Baseline, 4 months and 8 months

• Physical Activity measured by the short form of the International Physical Activity Questionnaire (IPAQ-SF)

  Baseline, 4 months and 8 months

• Muscle mass

  Baseline, 4 months and 8 months

• Compliance to the intervention

  Eight months from baseline

Study Arms (2)

Exercise

EXPERIMENTAL

This group will perform a multi-component exercise program twice a week for 16 weeks. The multi-component exercise program consists of endurance training, progressive strength exercises and balance exercises. The intervention will be individualised, but performed in groups of four to ten patients. The participants are also expected to do exercises on their own, at least once weekly.

Other: Exercise

Control

NO INTERVENTION

The participants in the control group will be encouraged to exercise on their own, according to the World Health Organization recommendations on physical activity for adults aged 65 and above.

Interventions

Exercise OTHER

A multi-component exercise program that consists of endurance training, progressive strength exercises and balance exercises.

Exercise

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)

You may qualify if:

• years or older, live in their own home, consent to participate in the program three times a week (twice a week outside their home), manage to walk with or without assistive device, and assessed by a doctor as able to tolerate the intervention.

You may not qualify if:

• Severe cognitive impairment (Mini-Mental State Examination (MMSE) score less than 20), have an expected lifespan less than one year, exercise more than twice a week, and score above nine points on the Short Physical Performance Battery.

Sponsors & Collaborators

• Oslo Metropolitan University: lead

Study Sites (1)

Diakonhjemmet Hospital

Oslo, 0370, Norway

Location

Related Publications (2)

• Sunde S, Hesseberg K, Skelton DA, Ranhoff AH, Pripp AH, Aaronaes M, Brovold T. Associations between health-related quality of life and physical function in older adults with or at risk of mobility disability after discharge from the hospital. Eur Geriatr Med. 2021 Dec;12(6):1247-1256. doi: 10.1007/s41999-021-00525-0. Epub 2021 Jun 9.

  PMID: 34106446 DERIVED

• Sunde S, Hesseberg K, Skelton DA, Ranhoff AH, Pripp AH, Aaronaes M, Brovold T. Effects of a multicomponent high intensity exercise program on physical function and health-related quality of life in older adults with or at risk of mobility disability after discharge from hospital: a randomised controlled trial. BMC Geriatr. 2020 Nov 11;20(1):464. doi: 10.1186/s12877-020-01829-9.

  PMID: 33176703 DERIVED

MeSH Terms

Conditions

Chest Pain; Pneumonia; Ischemic Attack, Transient; Stroke

Interventions

Exercise

Condition Hierarchy (Ancestors)

Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Respiratory Tract Infections; Infections; Lung Diseases; Respiratory Tract Diseases; Brain Ischemia; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Therese Brovold, Phd

  Oslo University College of Applied Science

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Phd-student

Study Record Dates

• First Submitted: September 5, 2016
• First Posted: September 19, 2016
• Study Start: September 29, 2016
• Primary Completion: January 30, 2020
• Study Completion: January 30, 2020
• Last Updated: August 4, 2020

Record last verified: 2020-08

Locations

NO (1)