Better Before - Better After: Prehabilitation Program for Older Patients Awaiting Total Hip Replacement

NCT03602105 | Active Not Recruiting

• 1 other identifier: 2018/503
• Study Type: interventional
• Target: 103
• Locations: 1 country
• Sites: 1

Brief Summary

Health professions need to prepare for the large increase in the number of older people with OA requiring health services including TJA surgery. Older age and poor physical function influences the postoperative prognosis of TJA. At discharge from hospital after TJA, studies have shown that gait speed can be severely impaired among older patients. The investigators hypothesize that an exercise program of 6-12 weeks will be beneficial for patients that are undergoing TJA.

Conditions

Arthritis of Hip

Keywords

exercise; prehabilitation; arthritis; quality of life; osteoarthritis; rehabilitation

Outcome Measures

Primary Outcomes (1)

• Change in gait speed

  40 meters Fast-Paced Walk test

  Change measure: Baseline, within one week after intervention, 6 weeks after intervention, 3 months after intervention, 6 months after intervention and 12 months after intervention

Secondary Outcomes (7)

• Change in physical function

  Change measure: Baseline, within one week after intervention, 6 weeks after intervention, 3 months after intervention, 6 months after intervention and 12 months after intervention

• Change in aerobic capacity

  1 week before intervention, directly after intervention as well as 6 and 12 weeks after TJA-surgery

• Change in transitional ambulation

  Change measure: Baseline, within one week after intervention, 6 weeks after intervention, 3 months after intervention, 6 months after intervention and 12 months after intervention

• Change in pain measured with numeric rating scale (NRS)

  Change measure: Baseline, within one week after intervention, 6 weeks after intervention and 3 months after intervention

• Length of stay in hospital

  From date of hospital admission until the date of hospital discharge, assessed up to 12 months

Study Arms (2)

Intervention group

ACTIVE COMPARATOR

Exercise interventions for 6-12 weeks. Adherence is monitored with day journals

Behavioral: Exercise

Control group

NO INTERVENTION

Care as usual

Interventions

Exercise BEHAVIORAL

Exercises in group and/or individually

Intervention group

Eligibility Criteria

• Age: 70 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)

You may qualify if:

• Participants 70 years or older living at home with residential address in the county of Oslo or Akershus scheduled for elective primary total hip replacement due to end-stage osteoarthritis.
• Harris Hip Score \>60.
• Participants must also be capable in Norwegian and be able to follow exercise sessions.

You may not qualify if:

• Patients with known rheumatoid arthritis or medical contraindications or those who are scheduled for revision of hip arthroplasty
• Unable to speak and understand the Norwegian language.
• Patients with neurological disorders affecting gait
• Medical contraindications for exercise

Sponsors & Collaborators

• Oslo Metropolitan University: lead

Study Sites (1)

OsloMet

Oslo, 0130, Norway

Location

Related Publications (5)

• Slatkowsky-Christensen B, Grotle M. Artrose i Norge. Norsk Epidemiologi 2008;18(1)

  BACKGROUND

• Wallace IJ, Worthington S, Felson DT, Jurmain RD, Wren KT, Maijanen H, Woods RJ, Lieberman DE. Knee osteoarthritis has doubled in prevalence since the mid-20th century. Proc Natl Acad Sci U S A. 2017 Aug 29;114(35):9332-9336. doi: 10.1073/pnas.1703856114. Epub 2017 Aug 14.

  PMID: 28808025 BACKGROUND

• Bitton R. The economic burden of osteoarthritis. Am J Manag Care. 2009 Sep;15(8 Suppl):S230-5.

  PMID: 19817509 BACKGROUND

• Svinoy OE, Nordbo JV, Pripp AH, Risberg MA, Bergland A, Borgen PO, Hilde G. The effect of prehabilitation for older patients awaiting total hip replacement. A randomized controlled trial with long-term follow up. BMC Musculoskelet Disord. 2025 Mar 6;26(1):227. doi: 10.1186/s12891-025-08468-4.

  PMID: 40050814 DERIVED

• Svinoy OE, Bergland A, Risberg MA, Pripp AH, Hilde G. Better before-better after: efficacy of prehabilitation for older patients with osteoarthritis awaiting total hip replacement-a study protocol for a randomised controlled trial in South-Eastern Norway. BMJ Open. 2019 Dec 30;9(12):e031626. doi: 10.1136/bmjopen-2019-031626.

  PMID: 31892650 DERIVED

MeSH Terms

Conditions

Motor Activity; Arthritis; Osteoarthritis

Interventions

Exercise

Condition Hierarchy (Ancestors)

Behavior; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Odd-Einar Svinøy, MSc

  OsloMet

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 6, 2018
• First Posted: July 26, 2018
• Study Start: March 1, 2019
• Primary Completion: May 30, 2024
• Study Completion: March 31, 2026
• Last Updated: November 2, 2023

Record last verified: 2023-11

Locations

NO (1)