Effects on Respiratory Patterns and Patient-ventilator Synchrony Using Pressure Support Ventilation

NCT02881385 | Unknown

• 1 other identifier: zhongdayiyuanICU
• Study Type: observational
• Target: 45
• Locations: 0 countries
• Sites: N/A

Brief Summary

Pressure Support Ventilation use Expiratory triggering sensitivity(Esense) to transfer inspiration to expiration,the value of Esense is fixed.That may lead to asynchrony between humans and ventilators,making people uncomfortable and prolonging weaning time.Some ventilators have auto cycle function Based on curves of pressure on respiratory patterns,it will make the transforming more synchrony with humans.Our prospective observational study will prove the superiority of the auto cycle function.

Conditions

Acute Respiratory Distress Syndrome; COPD; Post Operative

Keywords

Synchrony; Pressure Support Ventilation

Outcome Measures

Primary Outcomes (1)

• patient-ventilator synchrony using PSV mode between different ventilator for 180mins

  180mins after the patients involved

Secondary Outcomes (4)

• Patient Respiratory Patterns during Pressure Support Ventilation for 180mins

  180mins

• Patient gas exchange during Pressure Support Ventilation for 180mins

  180mins

• Effects on Respiratory Patterns in different Expiratory triggering sensitivity for 180mins

  180mins

• work of triggering and respiratory in different Expiratory triggering sensitivity for 180mins

  180mins

Study Arms (7)

E5 Esense 10%

PSV mode using E5 ventilator with Esense 10%

E5 Esense 30%

PSV mode using E5 ventilator with Esense 30%

E5 Esense 50%

PSV mode using E5 ventilator with Esense 50%

Servo-I Esense 10%

PSV mode using Servo-I ventilator with Esense 10%

Servo-I Esense 30%

PSV mode using Servo-I ventilator with Esense 30%

Servo-I Esense 50%

PSV mode using Servo-I ventilator with Esense 50%

E5 Esense autocycle

PSV mode using E5 ventilator with Esense Auto cycle

Eligibility Criteria

• Age: 18 Years - 85 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

mechanical ventilation adult people using PSV mode in ICU

You may qualify if:

• ARDS,COPD and Postoperative patient

You may not qualify if:

• variety of reasons can not be placed next to the bed by the nasal EAdi catheter

Sponsors & Collaborators

• Southeast University, China: lead

MeSH Terms

Conditions

Respiratory Distress Syndrome; Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases; Respiratory Tract Diseases; Respiration Disorders; Lung Diseases, Obstructive; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: CASE CROSSOVER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: physician

Study Record Dates

• First Submitted: July 30, 2016
• First Posted: August 29, 2016
• Study Start: September 1, 2016
• Primary Completion: August 1, 2017
• Study Completion: August 1, 2017
• Last Updated: September 13, 2016

Record last verified: 2016-09