NCT02875600

Brief Summary

To determine the difference in baseline MR flow measurements and post-prandial MR flow measurements between patients diagnosed with CGI and patients not diagnosed with CGI.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
62

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Aug 2016

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 12, 2016

Completed
20 days until next milestone

Study Start

First participant enrolled

August 1, 2016

Completed
22 days until next milestone

First Posted

Study publicly available on registry

August 23, 2016

Completed
5.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2021

Completed
Last Updated

March 9, 2021

Status Verified

March 1, 2021

Enrollment Period

5.3 years

First QC Date

July 12, 2016

Last Update Submit

March 8, 2021

Conditions

Keywords

chronic gastro-intestinal ischemiaoxygen deficiency of the gastro-intestinal tract

Outcome Measures

Primary Outcomes (1)

  • Determination of difference in baseline MR flow measurements and post prandial MR flow

    The difference in baseline MR flow measurements and post prandial MR flow measurements between patients diagnosed with CGI and patients not diagnosed with CGI (mL/min/kg)

    2.5 years

Secondary Outcomes (3)

  • Wich vessel or combination of vessels differentiate best

    2.5 years

  • The severity of abdominal pain

    20/30/40 minutes

  • Determination of difference in MR flow measurements before and after treatment for CGI

    2.5 years

Study Arms (1)

Nutri drink

EXPERIMENTAL

MRI flow measurements of mesenterial vessels and portal vein before and after stimulation with nutritional drink

Other: Nutri Drink

Interventions

To determine the difference in baseline MR flow measurements and post prandial MR flow measurements between patients diagnosed with CGI and patients not diagnosed with CGI

Nutri drink

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients suspected of CGI referred to our hospital for further analysis
  • Age ≥ 18 years
  • Patients who gave informed consent

You may not qualify if:

  • Age \< 18 years
  • Unable to give informed consent
  • Pregnancy
  • Contra-indications for MRI: a. Metal implants which cannot be removed. E.g. cardiac pacemakers/ICD, aneurysm clips, metal stents, artificial heart valve, cochlea/retinal implants, hearing aids, dentures with magnetic click system or with other metal accessories, tattoos with metallic dye, metal plates/pins/screws of bones, piercings b. Claustrophobia c. Inability to lie still for 1 hour to 1,5 hours
  • Other criteria the physician considers are not compatible with this study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Erasmusmc

Rotterdam, South Holland, 3015CE, Netherlands

RECRUITING

MeSH Terms

Conditions

IschemiaHypoxia

Condition Hierarchy (Ancestors)

Pathologic ProcessesPathological Conditions, Signs and SymptomsSigns and Symptoms, RespiratorySigns and Symptoms

Study Officials

  • Mohamed Ouhlous, md

    Erasmus Medical Center

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Laurens Groenendijk

CONTACT

Louisa Van Dijk, md

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
dr

Study Record Dates

First Submitted

July 12, 2016

First Posted

August 23, 2016

Study Start

August 1, 2016

Primary Completion

December 1, 2021

Study Completion

December 1, 2021

Last Updated

March 9, 2021

Record last verified: 2021-03

Data Sharing

IPD Sharing
Will not share

Locations