5 Year Follow-up of Adolescents With Knee Pain

NCT02873143 | Completed

• 1 other identifier: 2011-0020
• Study Type: observational
• Target: 540
• Locations: 0 countries
• Sites: N/A

Brief Summary

The prevalence of adolescent knee pain is 33%, and patellofemoral pain (PFP) is the most common diagnosis with a nontraumatic onset. The 5-year prognosis of adolescent PFP compared with other types of knee pain is unknown. In 2011, a cohort of 2200 adolescents aged 15 to 19 years answered an online questionnaire on musculoskeletal pain. Of these, 504 reported knee pain, and 153 of these were clinically diagnosed with PFP. Now, after 5 years, the 504 adolescents, as well as 252 randomly selected adolescents who did not report knee pain in 2011, will be contacted again to gain insights into their prognosis.

Conditions

Patellofemoral Pain Syndrome; Knee Pain

Outcome Measures

Primary Outcomes (1)

• Knee pain during the last week

  All subjects are asked if they experienced knee pain during the last week

  5 years

Secondary Outcomes (15)

• Knee pain during the last 30 days

  5 years

• Frequency of knee pain

  5 years

• When did your knee pain resolve

  5 years

• Pain in other regions of the body

  5 years

• Seeking medical attention for your knee pain

  5 years

Study Arms (1)

The APA2011 cohort

In September 2011, students at 4 upper secondary schools in Aalborg were invited to answer an online questionnaire and to be part of the APA2011 cohort. From 2846 potential responders, 2200 adolescents responded to the questionnaire, corresponding to a response rate of 77%. A total of 504 adolescents indicating knee pain at least monthly were successfully contacted (a response rate of 83% of those who reported their telephone numbers) and were asked standardized questions on the telephone. This forms the cohort of 504 adolescents with knee pain. In addition a random selected group of adolescents without knee pain in 2011 will be contacted and asked the same questions as those with knee pain.

Other: No intervention

Interventions

No intervention OTHER

No intervention

The APA2011 cohort

Eligibility Criteria

• Age: 15 Years - 19 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Probability Sample

Study Population

In September 2011, students at 4 upper secondary schools in Aalborg were invited to answer an online questionnaire and to be part of the APA2011 cohort. From 2846 potential responders, 2200 adolescents responded to the questionnaire, corresponding to a response rate of 77%. A total of 504 adolescents indicating knee pain at least monthly were successfully contacted (a response rate of 83% of those who reported their telephone numbers) and were asked standardized questions on the telephone. This forms the cohort of 504 adolescents with knee pain. In addition a random selected group of adolescents without knee pain in 2011 will be contacted and asked the same questions as those with knee pain.

You may not qualify if:

• concomitant injury or pain from the hip, lumbar spine, or other knee structures
• self-reported patellofemoral instability
• knee joint effusion.

Sponsors & Collaborators

• Aalborg University: lead
• Research Unit for General Practice in Aalborg: collaborator
• University of Southern Denmark: collaborator
• Copenhagen University Hospital, Denmark: collaborator

Related Publications (1)

• Rathleff MS, Holden S, Straszek CL, Olesen JL, Jensen MB, Roos EM. Five-year prognosis and impact of adolescent knee pain: a prospective population-based cohort study of 504 adolescents in Denmark. BMJ Open. 2019 May 28;9(5):e024113. doi: 10.1136/bmjopen-2018-024113.

  PMID: 31142518 DERIVED

MeSH Terms

Conditions

Patellofemoral Pain Syndrome

Condition Hierarchy (Ancestors)

Joint Diseases; Musculoskeletal Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Senior researcher

Study Record Dates

• First Submitted: August 16, 2016
• First Posted: August 19, 2016
• Study Start: September 1, 2016
• Primary Completion: December 1, 2016
• Study Completion: January 1, 2017
• Last Updated: January 27, 2017

Record last verified: 2017-01