Combined Plexus Block for Hip Fracture Surgery.

NCT03356704 | Completed

• 1 other identifier: RECHMPL17_0229
• Study Type: observational
• Target: 593
• Locations: 0 countries
• Sites: N/A

Brief Summary

Hip fracture surgery requires high risk anesthetic procedure for elderly patients (1). General anesthesia, continuous spinal anesthesia and peripheral nerve blocks are three anesthetic techniques possible. Continuous spinal anesthesia has proven its efficacity to provide an intraoperative haemodynamic stability wich guarantees good patients outcomes (2), in comparison with general anesthesia but there is poor evidence in the literature concerning the use of peripheral nerve blocks. The primary objective of this study was to compare intraoperative haemodynamic stability provides by peripheral nerve block versus general anesthesia and continuous spinal anesthesia. Secondary outcomes included : use of vasoactive drugs, opioids consumption, lengh of stay and inhospital mortality.

Conditions

Hip Fractures

Keywords

adults

Outcome Measures

Primary Outcomes (1)

• Intraoperative hypotension

  Decrease of at least 30% of mean arterial pressure

  1 day

Secondary Outcomes (4)

• measure the total consumption of the vasopressive molecules

  1 day

• Length of stay

  1 day

• compare the use of emergency antalgics

  1 day

• Inhospital mortality

  1 day

Study Arms (3)

General anaesthesia

Patient who had surgery for femoral neck fracture from January 2014 to December 2016 and had general anesthesia

Other: no intervention

continued spinal anesthesia

Patient who had surgery for femoral neck fracture from January 2014 to December 2016 and had continued spinal anesthesia

Other: no intervention

peripheral nerve blocks

Patient who had surgery for femoral neck fracture from January 2014 to December 2016 and had peripheral nerve blocks

Other: no intervention

Interventions

no intervention OTHER

Observational study

General anaesthesia; continued spinal anesthesia; peripheral nerve blocks

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

All adults patients operated for hip fracture between 1 January 2015 and 31 December 2016.

You may qualify if:

• Adult
• Hip fracture surgery

You may not qualify if:

• Multiple trauma victims
• Second hip fracture in same patient
• Single shot spinal anesthesia

Sponsors & Collaborators

• University Hospital, Montpellier: lead

Related Publications (1)

• Mounet B, Choquet O, Swisser F, Biboulet P, Bernard N, Bringuier S, Capdevila X. Impact of multiple nerves blocks anaesthesia on intraoperative hypotension and mortality in hip fracture surgery intermediate-risk elderly patients: A propensity score-matched comparison with spinal and general anaesthesia. Anaesth Crit Care Pain Med. 2021 Aug;40(4):100924. doi: 10.1016/j.accpm.2021.100924. Epub 2021 Jul 1.

  PMID: 34217841 DERIVED

MeSH Terms

Conditions

Hip Fractures

Condition Hierarchy (Ancestors)

Femoral Fractures; Fractures, Bone; Wounds and Injuries; Hip Injuries; Leg Injuries

Study Officials

• Xavier Capdevila, MD, PhD

  University Hospital, Montpellier

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 26, 2017
• First Posted: November 29, 2017
• Study Start: August 31, 2016
• Primary Completion: February 1, 2017
• Study Completion: October 26, 2017
• Last Updated: July 19, 2018

Record last verified: 2017-10