NCT02866864

Brief Summary

The investigators will evaluate sensitization to animal allergens and allergic symptom during contacting animal allergens in Korean veterinary researchers who attend their annual conference. The investigators will compare sensitization to animal allergen and other clinical and occupational factors between subjects who suffer from allergic symptom during contacting animal and those who do not.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
135

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Aug 2016

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 31, 2016

Completed
15 days until next milestone

First Posted

Study publicly available on registry

August 15, 2016

Completed
9 days until next milestone

Study Start

First participant enrolled

August 24, 2016

Completed
2 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 26, 2016

Completed
6 days until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2016

Completed
Last Updated

March 3, 2017

Status Verified

March 1, 2017

Enrollment Period

2 days

First QC Date

July 31, 2016

Last Update Submit

March 2, 2017

Conditions

Rhinitis, AllergicAsthmaDermatitis, AtopicUrticaria

Keywords

AllergenVeterinaryAllergyAnimals

Outcome Measures

Primary Outcomes (1)

  • Skin reactivity to animal allergen in skin prick test

    Mean diameter of wheal for animal allergen in skin prick test

    on the day of survey (day 1)

Secondary Outcomes (9)

  • Underlying allergic disease

    on the day of survey (day 1)

  • Family history of allergic disease

    on the day of survey (day 1)

  • Occupation

    on the day of survey (day 1)

  • Duration of occupation

    on the day of survey (day 1)

  • Contact animal

    on the day of survey (day 1)

  • +4 more secondary outcomes

Study Arms (2)

Subjects with animal allergy

Subjects who suffer from allergic symptom during contact with animal

Other: Animal allergy +

Subjects without animal allergy

Subjects who do not suffer from allergic symptom during contact with animal

Other: Animal allergy -

Interventions

Animal allergy -OTHER

Allergic symptom does not occur when subject contact animal

Subjects without animal allergy

Eligibility Criteria

Age19 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Korean Veterinary Researcher

You may qualify if:

  • Veterinary researchers attending their annual conference

You may not qualify if:

  • Veterinary researchers who receive medication including antihistamine (H1 and H2 blocker), systemic glucocorticosteroid which can effect on the result of skin prick test
  • Veterinary researchers who do not want to participate in this study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Gachon University Gil Medical Center

Incheon, 405-760, South Korea

Location

Related Publications (10)

  • Blair A, Hayes HM Jr. Cancer and other causes of death among U.S. veterinarians, 1966-1977. Int J Cancer. 1980 Feb 15;25(2):181-5. doi: 10.1002/ijc.2910250203.

    PMID: 7390647BACKGROUND

  • Elbers AR, Blaauw PJ, de Vries M, van Gulick PJ, Smithuis OL, Gerrits RP, Tielen MJ. Veterinary practice and occupational health. An epidemiological study of several professional groups of Dutch veterinarians. I. General physical examination and prevalence of allergy, lung function disorders, and bronchial hyperreactivity. Vet Q. 1996 Dec;18(4):127-31. doi: 10.1080/01652176.1996.9694711.

    PMID: 8972059BACKGROUND

  • Samadi S, Spithoven J, Jamshidifard AR, Berends BR, Lipman L, Heederik DJ, Wouters IM. Allergy among veterinary medicine students in The Netherlands. Occup Environ Med. 2012 Jan;69(1):48-55. doi: 10.1136/oem.2010.064089. Epub 2011 May 31.

    PMID: 21632519BACKGROUND

  • Park YB, Mo EK, Lee JY, Kim JH, Kim CH, Hyun IG, Choi JH. Association between pet ownership and the sensitization to pet allergens in adults with various allergic diseases. Allergy Asthma Immunol Res. 2013 Sep;5(5):295-300. doi: 10.4168/aair.2013.5.5.295. Epub 2013 Jun 25.

    PMID: 24003386BACKGROUND

  • Moghtaderi M, Farjadian S, Abbaszadeh Hasiri M. Animal allergen sensitization in veterinarians and laboratory animal workers. Occup Med (Lond). 2014 Oct;64(7):516-20. doi: 10.1093/occmed/kqu097. Epub 2014 Aug 7.

    PMID: 25104279RESULT

  • Lutsky I, Baum GL, Teichtahl H, Mazar A, Aizer F, Bar-Sela S. Occupational respiratory disease in veterinarians. Ann Allergy. 1985 Aug;55(2):153-6.

    PMID: 4025958RESULT

  • Susitaival P, Kirk JH, Schenker MB. Atopic symptoms among California veterinarians. Am J Ind Med. 2003 Aug;44(2):166-71. doi: 10.1002/ajim.10253.

    PMID: 12874849RESULT

  • Krakowiak A, Wiszniewska M, Krawczyk P, Szulc B, Wittczak T, Walusiak J, Palczynski C. Risk factors associated with airway allergic diseases from exposure to laboratory animal allergens among veterinarians. Int Arch Occup Environ Health. 2007 May;80(6):465-75. doi: 10.1007/s00420-006-0153-0. Epub 2006 Oct 5.

    PMID: 17021840RESULT

  • Will LA, Nassif EG, Engen RL, Patterson RA, Zimmerman D. Allergy and pulmonary impairment in Iowa veterinarians. N Engl Reg Allergy Proc. 1987 May-Jun;8(3):173-7. doi: 10.2500/108854187778984645.

    PMID: 3477686RESULT

  • Samadi S, Wouters IM, Heederik DJ. A review of bio-aerosol exposures and associated health effects in veterinary practice. Ann Agric Environ Med. 2013;20(2):206-21.

    PMID: 23772565RESULT

MeSH Terms

Conditions

Rhinitis, AllergicAsthmaDermatitis, AtopicUrticariaHypersensitivity

Condition Hierarchy (Ancestors)

RhinitisNose DiseasesRespiratory Tract DiseasesRespiratory HypersensitivityOtorhinolaryngologic DiseasesHypersensitivity, ImmediateImmune System DiseasesBronchial DiseasesLung Diseases, ObstructiveLung DiseasesSkin Diseases, GeneticGenetic Diseases, InbornCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesDermatitisSkin DiseasesSkin and Connective Tissue DiseasesSkin Diseases, EczematousSkin Diseases, Vascular

Study Officials

  • Sang Min Lee, MD, PhD

    Gachon University Gil Medical Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
ECOLOGIC OR COMMUNITY
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant professor

Study Record Dates

First Submitted

July 31, 2016

First Posted

August 15, 2016

Study Start

August 24, 2016

Primary Completion

August 26, 2016

Study Completion

September 1, 2016

Last Updated

March 3, 2017

Record last verified: 2017-03

Data Sharing

IPD Sharing
Will not share

Individual participant will be informed of results of questionnaires and skin prick test immediately after they complete questionnaires and skin prick test

Locations

KR(1)