Key Insights

Highlights

Success Rate

90% trial completion (above average)

Published Results

47 trials with published results (23%)

Research Maturity

146 completed trials (71% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 30/100

Termination Rate

8.3%

17 terminated out of 205 trials

Success Rate

89.6%

+3.1% vs benchmark

Late-Stage Pipeline

31%

63 trials in Phase 3/4

Results Transparency

32%

47 of 146 completed with results

Key Signals

47 with results90% success17 terminated

Data Visualizations

Phase Distribution

177Total
Not Applicable (33)
Early P 1 (2)
P 1 (35)
P 2 (44)
P 3 (38)
P 4 (25)

Trial Status

Completed146
Terminated17
Unknown14
Active Not Recruiting13
Recruiting10
Withdrawn2

Trial Success Rate

89.6%

Benchmark: 86.5%

Based on 146 completed trials

Clinical Trials (205)

Showing 20 of 20 trials
NCT05492578Phase 2Enrolling By InvitationPrimary

Long-Term Safety and Efficacy Evaluation of Amlitelimab in Participants of Previous Amlitelimab Moderate to Severe Atopic Dermatitis Clinical Trials

NCT01631617Phase 2Recruiting

Effects of Treatments on Atopic Dermatitis

NCT06686628Phase 1CompletedPrimary

An Open-label, DDI Study to Investigate the Effects of Amlitelimab on the PK of Selected Cytochrome P450 Substrates

NCT05769777Phase 2Active Not RecruitingPrimary

Open Label, Long-term Study Evaluating Safety and Efficacy of Subcutaneous Amlitelimab in Participants Aged 12 Years and Older With Moderate to Severe Atopic Dermatitis

NCT06899204Recruiting

Real World Efficiency of Abrocitinib Treatment at Patients With Moderate to Severe Atopic Dermatitis Who Had Inadequate Response to Previous Biologic Therapies.

NCT06790121Phase 2CompletedPrimary

A Study to Investigate the Efficacy and Safety of Subcutaneous Lunsekimig (SAR443765) Compared With Placebo in Adult Participants With Moderate-to-severe Atopic Dermatitis

NCT06526182Phase 3Active Not RecruitingPrimary

A Study of Lebrikizumab Treatment in Adults and Adolescents With Moderate-to-Severe Atopic Dermatitis

NCT06407934Phase 3Active Not RecruitingPrimary

A Study to Evaluate the Treatment Response and Safety of Two Dose Regimens of Subcutaneous Amlitelimab Compared With Treatment Withdrawal in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis

NCT07540442Phase 3Not Yet RecruitingPrimary

A Phase III Study of MG-K10 in Adolescents With Moderate-to-Severe Atopic Dermatitis

NCT06015308Phase 2CompletedPrimary

A Study to Investigate Vaccine Responses in Subcutaneous Amlitelimab Treated Atopic Dermatitis Participants Aged 18 Years and Older Compared With Placebo

NCT07230860Phase 2RecruitingPrimary

A Study of JNJ-95597528 in Participants With Moderate to Severe Atopic Dermatitis

NCT05983068Phase 4Active Not RecruitingPrimary

A Study of Long-term Effect of Dupilumab on Skin Barrier Function in Pediatric Participants With Atopic Dermatitis

NCT06241118Phase 3RecruitingPrimary

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab on Background Topical Corticosteroids Therapy in Participants Aged 12 Years and Older With Moderate-to-severe AD Who Have Had an Inadequate Response to Prior Biologic Therapy or an Oral JAK Inhibitor

NCT06181435Phase 3CompletedPrimary

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (COAST 2)

NCT06881251Phase 2Active Not RecruitingPrimary

A Study of JNJ-95475939 in the Treatment of Participants With Moderate to Severe Atopic Dermatitis (AD)

NCT06094179Phase 1Active Not RecruitingPrimary

Evaluate the Safety, Tolerability of BAT6026

NCT07367932Phase 4Not Yet RecruitingPrimary

Comparative Study of Crisaborole vs. Tacrolimus in Atopic Dermatitis

NCT03422822Phase 3CompletedPrimary

Study to Evaluate Efficacy and Safety of PF-04965842 With or Without Topical Medications in Subjects Aged 12 Years and Older With Moderate to Severe Atopic Dermatitis

NCT06173284Phase 3CompletedPrimary

Evaluation of 611(Recombinant Humanized Anti-interleukin-4 Receptor Alpha IgG4 Monoclonal Antibody) in Chinese Adults With Moderate to Severe Atopic Dermatitis

NCT04684485Phase 2CompletedPrimary

To Assess the Efficacy and Safety of SCD-044 in the Treatment of Moderate to Severe Atopic Dermatitis

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