Pronostic Value of Endothelial Dysfunction in Heart Failure

NCT02859636 | Terminated DMC

• 1 other identifier: P/2012/140
• Study Type: observational
• Target: 7
• Locations: 0 countries
• Sites: N/A

Brief Summary

The main objective is to evaluate the pronostic value of endothelial dysfonction in acute heart failure on a combined criteria associating cardiovascular mortality, nex hospitalisation for decompensated heart failure, cardiac graft or ventricular assistance 2 month and 1 year before acute heart failure.

Conditions

Heart Decompensation; Cardiac Failure

Eligibility Criteria

• Age: 18 Years - 81 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with more than 18 years and less than 81 years, hospitalized for acute heart failure with left ventricular impairment (LVEF \< 45%)

You may qualify if:

• patients hospitalized for acute heart fialure with Left Ventricular Ejection Fraction (LVEF) \< 45 % on echocardiography

You may not qualify if:

• Informed consent form not signed
• Cardiogenic, septic or hemorragic shock
• Acute coronary syndrom with elevated troponin
• valvular surgery or aorto-coronary graft during next 3 months
• Cancer
• Pregnancy
• life expectancy over than 1 year
• chronic renal impairment

Sponsors & Collaborators

• Centre Hospitalier Universitaire de Besancon: lead

Biospecimen

Retention: SAMPLES WITHOUT DNA

serum samples, endothelial progenitors

MeSH Terms

Conditions

Heart Failure

Condition Hierarchy (Ancestors)

Heart Diseases; Cardiovascular Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 2, 2016
• First Posted: August 9, 2016
• Study Start: October 1, 2012
• Primary Completion: March 1, 2016
• Study Completion: March 1, 2016
• Last Updated: August 9, 2016

Record last verified: 2016-08