Specke Tracking Echocardiography And Filling Pressures

NCT02854865 | Unknown

• 1 other identifier: 1791/2012
• Study Type: observational
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

Determining the LV filling pressure is a key element in the diagnosis and management of patients with suspected decompensated heart failure. The aim of the present study is to assess whether a systolic 2D-STEderived parameter, global longitudinal peak systolic strain (GLPSS), acquired by transoesophageal echocardiography (TEE) is superior to the E/Ea ratio in the estimation of the LVFP measured as the pulmonary capillary wedge pressure (PCWP) in patients during cardiac surgery. Automated function image (AFI) algorithm is a novel method based on 2D strain imaging that enables the simultaneous quantification of myocardial strain in different left ventricular segments; its 3-click method minimizes variability related to a manual training of endocardial border required in an usual 2D-strain analysis. AFI provides GLPSS by averaging mid-oesophageal 4-, 2- chamber and long axis views. The study is a prospective observational single-center cohort study. 30 Patients scheduled for elective cardiac surgery will be included in the study group. The study is designed to assess whether GLPSS measured during cardiac surgery using AFI is superior to E/Ea ratio in estimation of LVFP measured as PCWP.

Conditions

Echocardiography, 2-D

Outcome Measures

Primary Outcomes (1)

• global longitudinal peak systolic strain (GLPSS) acquired by transoesophageal echocardiography

  postoperative offline measurement of strain

  30min after Induction of anaesthesia

Study Arms (1)

Echocardiography

assess whether GLPSS measured during cardiac surgery using AFI is superior to E/Ea ratio in estimation of LVFP measured as PCWP

Other: echocardiography

Interventions

echocardiography OTHER

assess whether GLPSS measured during cardiac surgery using AFI is superior to E/Ea ratio in estimation of LVFP measured as PCWP

Echocardiography

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

all patients schedulded for elective cardiac surgery

You may qualify if:

• patients scheduled for elective cardiac surgery

You may not qualify if:

• non-sinus rhythm
• severe mitral regurgitation
• mitral stenosis
• prosthetic mitral valve

Sponsors & Collaborators

• Medical University of Vienna: lead

Study Sites (1)

Medical university of vienna, General hospital of Vienna

Vienna, 1090, Austria

RECRUITING

Study Officials

• Ulrike Weber, M.D.

  Medical University of Vienna

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: M.D.

Study Record Dates

• First Submitted: July 20, 2016
• First Posted: August 4, 2016
• Study Start: January 1, 2015
• Primary Completion: June 1, 2018
• Study Completion: December 1, 2018
• Last Updated: October 20, 2017

Record last verified: 2017-10

Data Sharing

• IPD Sharing: Will not share

Locations

AU (1)