NCT02851719

Brief Summary

To test whether biofeedback (BF) added to pelvic floor muscle training (PFMT) promotes additional benefits over PFMT alone in the stress urinary incontinence (SUI) treatment.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
72

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Mar 2011

Longer than P75 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2011

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2011

Completed
3.5 years until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2014

Completed
1.9 years until next milestone

First Submitted

Initial submission to the registry

July 28, 2016

Completed
5 days until next milestone

First Posted

Study publicly available on registry

August 2, 2016

Completed
Last Updated

August 3, 2016

Status Verified

August 1, 2016

Enrollment Period

Same day

First QC Date

July 28, 2016

Last Update Submit

August 1, 2016

Conditions

Keywords

Urinary Incontinence, StressPelvic FloorExercisePatient Compliance

Outcome Measures

Primary Outcomes (1)

  • Change in pad test

    To quantify the severity of SUI and as the tool to estimate objective cure rate

    Baseline, after 3 months of supervised treatment and at 9-month follow-up

Secondary Outcomes (7)

  • Change in 7-Day Voiding Diary

    Baseline, after 3 months of supervised treatment and at 9-month follow-up

  • Change in pelvic floor muscle function (Oxford Grading Scale)

    Baseline, after 3 months of supervised treatment and at 9-month follow-up

  • Change in pelvic floor muscle function (Peritron manometer)

    Baseline, after 3 months of supervised treatment and at 9-month follow-up

  • Change in Incontinence Quality-of-Life Questionnaire (I-QoL)

    Baseline, after 3 months of supervised treatment and at 9-month follow-up

  • Subjective cure of SUI ("satisfied" or "dissatisfied")

    After 3 months of supervised treatment and at 9-month follow-up

  • +2 more secondary outcomes

Study Arms (2)

BF group

EXPERIMENTAL

24 outpatient sessions of the PFMT (twice a week) using manometric-based BF equipment and daily home PFMT exercises.

Other: PFMT with biofeedback + Home PFMT

PFMT group

ACTIVE COMPARATOR

24 outpatient sessions (twice a week) of PFMT without BF and daily home PFMT exercises.

Other: PFMT without biofeedback + Home PFMT

Interventions

24 outpatient sessions PFMT with biofeedback (twice a week). Simultaneously, it was prescribed a home exercise daily program during three months (supervised treatment).

Also known as: Biofeedback
BF group

24 outpatient sessions PFMT without biofeedback (twice a week). Simultaneously, it was prescribed a home exercise daily program during three months (supervised treatment).

Also known as: PFMT alone
PFMT group

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • SUI and mixed urinary incontinence with predominant symptoms of SUI with ≥ 2 g of leakage measured by pad test

You may not qualify if:

  • younger than 18 years old
  • chronic degenerative diseases
  • pelvic organ prolapse greater than stage I by POP-Q
  • neurologic or psychiatric diseases
  • previously undergone pelvic floor re-education programs and/or previous pelvic floor surgeries

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Urinary Incontinence, StressMotor ActivityPatient Compliance

Interventions

Biofeedback, Psychology

Condition Hierarchy (Ancestors)

Urinary IncontinenceUrination DisordersUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesLower Urinary Tract SymptomsUrological ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsBehaviorPatient Acceptance of Health CareTreatment Adherence and ComplianceHealth Behavior

Intervention Hierarchy (Ancestors)

Mind-Body TherapiesComplementary TherapiesTherapeuticsBehavior TherapyPsychotherapyBehavioral Disciplines and ActivitiesFeedback, Psychological

Study Officials

  • Fatima F Fitz, M.Sc

    Federal University of São Paulo

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Physical Therapist

Study Record Dates

First Submitted

July 28, 2016

First Posted

August 2, 2016

Study Start

March 1, 2011

Primary Completion

March 1, 2011

Study Completion

September 1, 2014

Last Updated

August 3, 2016

Record last verified: 2016-08