NCT02599051

Brief Summary

A randomized control trial to compare the efficacy of the single incision mini-sling to the transobturator sling

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
98

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Nov 2008

Typical duration for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2008

Completed
2.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2011

Completed
4.8 years until next milestone

First Submitted

Initial submission to the registry

November 3, 2015

Completed
3 days until next milestone

First Posted

Study publicly available on registry

November 6, 2015

Completed
7.7 years until next milestone

Results Posted

Study results publicly available

July 20, 2023

Completed
Last Updated

July 20, 2023

Status Verified

June 1, 2023

Enrollment Period

2.2 years

First QC Date

November 3, 2015

Results QC Date

August 22, 2018

Last Update Submit

June 28, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Objective Stress Urinary Incontinence

    The primary outcome was presence of leakage during cough stress test(CST) on examination

    1 year

Secondary Outcomes (5)

  • Quality of Life Questionnaire UDI-6

    1 year

  • Subjective Patient Reported Recurrent or Persistent Stress Urinary Incontinence

    1 year

  • Number of Participants Who Completed Self- Assessment of Cure

    1 year

  • Quality of Life Questionnaire IIQ-7

    1 year

  • Quality of Life Questionnaire ICIQ

    1 year

Study Arms (2)

Monarc

ACTIVE COMPARATOR

Placement of a transobturator monarc sling for stress urinary incontinence

Device: Monarc

Mini-arc

EXPERIMENTAL

Placement of a single incision mini-arc sling for stress urinary incontinence

Device: Mini-arc

Interventions

Mini-arcDEVICE

We will place a single incision sling at the time of surgery for stress urinary incontinence

Also known as: single incision sling
Mini-arc
MonarcDEVICE

We will place a transobturator sling at the time of surgery for stress urinary incontinence

Also known as: transobturator sling
Monarc

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with urodynamically proven stress urinary incontinence who were planning on undergoing surgery for treatment.

You may not qualify if:

  • Patients with prior incontinence surgery, a urodynamic diagnosis of intrinsic sphincter deficiency and mixed incontinence with a predominance of detrusor overactivity were excluded.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Carter E, Johnson EE, Still M, Al-Assaf AS, Bryant A, Aluko P, Jeffery ST, Nambiar A. Single-incision sling operations for urinary incontinence in women. Cochrane Database Syst Rev. 2023 Oct 27;10(10):CD008709. doi: 10.1002/14651858.CD008709.pub4.

MeSH Terms

Conditions

Urinary Incontinence, Stress

Interventions

Suburethral Slings

Condition Hierarchy (Ancestors)

Urinary IncontinenceUrination DisordersUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesLower Urinary Tract SymptomsUrological ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Prostheses and ImplantsEquipment and Supplies

Results Point of Contact

Title
G W Davila
Organization
Cleveland Clinic Florida

Study Officials

  • G Willy Davila, MD

    Cleveland Clinic Florida

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
coordinator

Study Record Dates

First Submitted

November 3, 2015

First Posted

November 6, 2015

Study Start

November 1, 2008

Primary Completion

January 1, 2011

Study Completion

January 1, 2011

Last Updated

July 20, 2023

Results First Posted

July 20, 2023

Record last verified: 2023-06

Data Sharing

IPD Sharing
Will not share