NCT02836717

Brief Summary

The aim of this study is to determine the success rate, the success duration, the complication rate, maintenance effort and quality of life several years after sacral nerve modulation (SNM) treatment for constipation or stool incontinence.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
101

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Apr 2016

Shorter than P25 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2016

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

June 22, 2016

Completed
27 days until next milestone

First Posted

Study publicly available on registry

July 19, 2016

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2016

Completed
7 years until next milestone

Results Posted

Study results publicly available

September 18, 2023

Completed
Last Updated

September 18, 2023

Status Verified

November 1, 2022

Enrollment Period

5 months

First QC Date

June 22, 2016

Results QC Date

July 11, 2019

Last Update Submit

November 15, 2022

Conditions

Keywords

sacral nerve modulationquality of lifestimulator maintenanceSNM

Outcome Measures

Primary Outcomes (1)

  • Percentage of Patients Considering the Treatment a Success After 5 Years

    Treatment is considered a success if a patients reports a subjective 50% reduction in disease related complaints

    5 years

Secondary Outcomes (6)

  • Percentage of Patients Considering the Treatment a Success After 1 Years

    1 year

  • Percentage of Patients Considering the Treatment a Success After 3 Years

    3 year

  • Number of Patients at Risk After 1 Year

    1 year

  • Number of Patients at Risk After 3 Years

    3 year

  • Number of Patients at Risk After 5 Years

    5 year

  • +1 more secondary outcomes

Interventions

electric stimulation of the sacral nerve using an implanted electrode and stimulator

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

patients starting an SNM treatment for constipation or fecal incontinence between March 2006 and October 2015

You may qualify if:

  • Patients who had received an SNM treatment in the last 10 years

You may not qualify if:

  • pudendal nerve stimulation
  • refusal to allow use of clinical data for retrospective data analysis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Widmann B, Galata C, Warschkow R, Beutner U, Ogredici O, Hetzer FH, Schmied BM, Post S, Marti L. Success and Complication Rates After Sacral Neuromodulation for Fecal Incontinence and Constipation: A Single-center Follow-up Study. J Neurogastroenterol Motil. 2019 Jan 31;25(1):159-170. doi: 10.5056/jnm17106.

MeSH Terms

Conditions

ConstipationFecal Incontinence

Condition Hierarchy (Ancestors)

Signs and Symptoms, DigestiveSigns and SymptomsPathological Conditions, Signs and SymptomsRectal DiseasesIntestinal DiseasesGastrointestinal DiseasesDigestive System Diseases

Limitations and Caveats

Observed death was unrelated to study treatment or study participation

Results Point of Contact

Title
Dr Lukas Marti
Organization
Department of Surgery, Cantonal Hospital St. Gallen

Study Officials

  • Lukas Marti, MD

    Cantonal Hospital of St. Gallen

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

June 22, 2016

First Posted

July 19, 2016

Study Start

April 1, 2016

Primary Completion

September 1, 2016

Study Completion

September 1, 2016

Last Updated

September 18, 2023

Results First Posted

September 18, 2023

Record last verified: 2022-11

Data Sharing

IPD Sharing
Will not share