Respiratory Weaning Following Cardiac Surgery.

NCT02821429 | Withdrawn

• 1 other identifier: RC31/15/7850
• Study Type: observational
• Target: N/A
• Locations: 1 country
• Sites: 1

Brief Summary

Respiratory weaning failure worsens prognostic of patients following on-pump cardiac surgery. There are increasing evidences that pulmonary, diaphragmatic or cardiologic echographies are useful in order to improve this critical medical status. Based both on a previous study conducted in the critical care unit of Purpan and on literature we hypothesize that a combined thoracic echography score could be of interest. We make the hypothesis that the use of a score based on thoracic combined echography (ETC = cardiac, pulmonary and diaphragmatic) allows to predict the failure of respiratory weaning in cardiac surgery and allows to improve the characterization of the causes of this failure

Conditions

Respiratory Insufficiency

Keywords

Respiratory weaning; Pulmonary ventilation

Outcome Measures

Primary Outcomes (1)

• Evaluation of predictive value of combined Thoracic Echography (ETC) as assessed by difference in the ETC score before and after extubation

  1 hour after the weaning test and 48h after

Secondary Outcomes (2)

• Evaluation of predictive value of combined Thoracic Echography (ETC) as assessed T tube Test score difference between patient who succeed or failed the weaning test

  H0 and 48h after the weaning test

• Evaluation of diagnostic value of combined Thoracic Echography (ETC) after failure to weaning test as assessed be ECT scores collected

  H0, H1 and H48

Study Arms (1)

Patient with mechanical ventilation

Patient will be followed with combined Thoracic Echography Record

Other: Combined Thoracic Echography Record

Interventions

Combined Thoracic Echography Record OTHER

This examination will be done to do the longitudinal follow-up of the patient

Patient with mechanical ventilation

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients will be recruited during the pre anesthetic visit

You may qualify if:

• Adult (\> 18 years old) beneficiating of mechanical ventilation following cardiac surgery
• Weaning test period
• Patient insured under the French social security system

You may not qualify if:

• Tracheostomy
• Neurological disorders
• Need for prophylactic non invasive ventilation.
• Global obstructive lung disease with a forced expiratory volume \< 50%.
• Judicial protection
• Patient already included in a trial still running.
• Pregnancy

Sponsors & Collaborators

• University Hospital, Toulouse: lead

Study Sites (1)

University Hospital Toulouse

Toulouse, 31000, France

Location

MeSH Terms

Conditions

Respiratory Insufficiency

Condition Hierarchy (Ancestors)

Respiration Disorders; Respiratory Tract Diseases

Study Officials

• Nicolas MAYEUR, MD

  University Hospital, Toulouse

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 28, 2016
• First Posted: July 1, 2016
• Study Start: January 1, 2015
• Primary Completion: January 1, 2019
• Study Completion: January 1, 2019
• Last Updated: June 6, 2019

Record last verified: 2019-06

Locations

FR (1)