Incidence and Risk Factors of Extubation Failure in Pediatric Resuscitation

NCT03129802 | Unknown

• 1 other identifier: 6310
• Study Type: observational
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The failure of extubation in pediatric resuscitation is most often described as the need for reintubation within 48 hours after extubation. The failure rate of extubation in pediatric intensive care varies in the literature there is 4 to 22% failure. These failures result in increased mortality, morbidity with a use of larger tracheostomy, a prolonged residence time. Some risk factors are well defined in the literature as the duration of intubation, ENT and neurological history, the persistence of a respiratory disease, a high level of sedation. Other factors are more controversial as age, ventilatory parameters just before extubation before extubation blood gases, the interest of a leak test. Also pediatric populations are extremely heterogeneous, so the investigators would like to highlight to extubation failure risk factors in Hautepierre pediatric ICU to better support these high-risk children.

Conditions

Respiratory Insufficiency

Keywords

extubation; pediatric resuscitation; reintubation; failures of extubation.; Respiratory Insufficiency

Outcome Measures

Primary Outcomes (1)

• Failure of extubation

  need for a new intubation within the first 48 hours after extubation

Eligibility Criteria

• Age: Up to 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Probability Sample

Study Population

Children hospitalized in pediatric intensive care, under 18 years, intubated, ventilated for more than 2 hours and for which planning extubation or intubated children for whom an unplanned extubation just happened.

You may qualify if:

• Children hospitalized in pediatric intensive care, under 18 years, intubated, ventilated for more than 2 hours and for which planning extubation or intubated children for whom an unplanned extubation just happened.
• Children whose holding parental authority are not opposed to the use of clinical data from their child for research purposes.

You may not qualify if:

• Refusal to participate in the study

Sponsors & Collaborators

• University Hospital, Strasbourg, France: lead

Study Sites (1)

Service de Reanimation Pediatrique Specialisee - S. Continue

Strasbourg, 67091, France

RECRUITING

MeSH Terms

Conditions

Respiratory Insufficiency

Condition Hierarchy (Ancestors)

Respiration Disorders; Respiratory Tract Diseases

Central Study Contacts

Anne-Sophie Guilbert, MD

CONTACT

33 (0)3 88 12 73 20; anne-sophie.guilbert@chru-strasbourg.fr

Lucie PETITDEMANGE

CONTACT

33 (0)3 88 12 73 20; lucie.petitdemange@chru-strasbourg.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 17, 2016
• First Posted: April 26, 2017
• Study Start: July 1, 2016
• Primary Completion: August 1, 2017
• Study Completion: August 1, 2017
• Last Updated: May 11, 2017

Record last verified: 2016-06

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)